> top > projects > sonoma2 > docs > PubMed:16371368 > annotations
sonoma2  

PubMed:16371368 JSONTXT 55 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T-0 108-117 VAR denotes Mutations
T-1 121-126 GENE denotes SHP-2
T-2 144-149 REG denotes cause
T-3 150-165 POSREG denotes hyperactivation
T-4 173-191 MPA denotes catalytic activity
T-5 202-212 REG denotes identified
T-6 222-231 DISEASE denotes leukemias
T-7 246-278 DISEASE denotes juvenile myelomonocytic leukemia
T-8 289-302 REG denotes characterized
T-9 306-322 POSREG denotes hypersensitivity
T-10 326-350 CPA denotes myeloid progenitor cells
T-11 354-402 GENE denotes granulocyte macrophage colony-stimulating factor
T-12 407-425 GENE denotes interleukin (IL)-3
T-13 470-486 POSREG denotes gain-of-function
T-14 488-491 POSREG denotes GOF
T-15 493-502 VAR denotes mutations
T-16 512-518 REG denotes induce
T-17 519-545 DISEASE denotes hematopoietic malignancies
T-18 609-614 GENE denotes SHP-2
T-19 615-620 REG denotes plays
T-20 642-646 GENE denotes IL-3
T-21 729-743 POSREG denotes overexpression
T-22 779-789 NEGREG denotes attenuates
T-23 790-803 GENE denotes IL-3-mediated
T-24 804-831 CPA denotes hematopoietic cell function
T-25 840-851 POSREG denotes accelerated
T-26 852-869 MPA denotes dephosphorylation
T-27 873-878 GENE denotes STAT5
T-28 939-948 DISEASE denotes leukemias
T-29 964-974 REG denotes attributed
T-30 982-991 POSREG denotes increased
T-31 992-1010 MPA denotes catalytic activity
T-32 1014-1017 POSREG denotes GOF
T-33 1018-1024 VAR denotes mutant
T-34 1025-1030 GENE denotes SHP-2
T-35 1032-1035 POSREG denotes GOF
T-36 1043-1048 GENE denotes SHP-2
T-37 1059-1065 POSREG denotes gained
T-38 1077-1087 MPA denotes capacities
T-39 1131-1138 REG denotes effects
T-40 1144-1147 POSREG denotes GOF
T-41 1148-1156 VAR denotes mutation
T-42 1167-1172 GENE denotes SHP-2
T-43 1182-1209 CPA denotes hematopoietic cell function
T-44 1214-1218 GENE denotes IL-3
T-45 1283-1288 GENE denotes SHP-2
T-46 1320-1333 VAR denotes E76K mutation
T-47 1334-1340 REG denotes caused
T-48 1341-1367 DISEASE denotes myeloproliferative disease
T-49 1410-1419 NEGREG denotes decreased
T-50 1420-1443 CPA denotes hematopoietic potential
T-51 1494-1507 VAR denotes E76K mutation
T-52 1548-1557 POSREG denotes increased
T-53 1558-1570 INTERACTION denotes interactions
T-54 1574-1580 VAR denotes mutant
T-55 1581-1586 GENE denotes SHP-2
T-56 1592-1596 GENE denotes Grb2
T-57 1598-1602 GENE denotes Gab2
T-58 1608-1611 GENE denotes p85
T-59 1613-1620 REG denotes leading
T-60 1624-1639 POSREG denotes hyperactivation
T-61 1664-1709 PATHWAY denotes phosphatidylinositol 3-kinase (PI3K) pathways
T-62 1748-1756 POSREG denotes increase
T-63 1764-1782 MPA denotes catalytic activity
T-64 1784-1801 MPA denotes dephosphorylation
T-65 1805-1810 GENE denotes STAT5
T-66 1814-1819 GENE denotes SHP-2
T-67 1820-1824 VAR denotes E76K
T-68 1829-1837 NEGREG denotes dampened
T-69 1875-1880 GENE denotes SHP-2
T-70 1905-1919 VAR denotes C459S mutation
T-71 1947-1955 POSREG denotes increase
T-72 1960-1971 INTERACTION denotes interaction
T-73 1977-1981 GENE denotes Gab2
T-74 1989-1996 POSREG denotes enhance
T-75 2019-2031 PATHWAY denotes PI3K pathway
T-76 2095-2103 POSREG denotes elevated
T-77 2104-2122 MPA denotes catalytic activity
T-78 2136-2143 REG denotes changes
T-79 2171-2183 INTERACTION denotes interactions
T-80 2192-2195 POSREG denotes GOF
T-81 2203-2208 GENE denotes SHP-2
T-82 2237-2241 REG denotes play
T-83 2255-2259 REG denotes role
R-0 T-0 T-2 CauseOf Mutations,cause
R-1 T-0 T-3 CauseOf Mutations,hyperactivation
R-10 T-7 T-2 ThemeOf juvenile myelomonocytic leukemia,cause
R-11 T-7 T-3 ThemeOf juvenile myelomonocytic leukemia,hyperactivation
R-12 T-7 T-5 ThemeOf juvenile myelomonocytic leukemia,identified
R-13 T-7 T-8 ThemeOf juvenile myelomonocytic leukemia,characterized
R-14 T-7 T-9 ThemeOf juvenile myelomonocytic leukemia,hypersensitivity
R-15 T-9 T-8 ThemeOf hypersensitivity,characterized
R-16 T-10 T-9 ThemeOf myeloid progenitor cells,hypersensitivity
R-17 T-10 T-8 ThemeOf myeloid progenitor cells,characterized
R-18 T-11 T-8 ThemeOf granulocyte macrophage colony-stimulating factor,characterized
R-19 T-11 T-9 ThemeOf granulocyte macrophage colony-stimulating factor,hypersensitivity
R-2 T-0 T-9 CauseOf Mutations,hypersensitivity
R-20 T-11 T-10 ThemeOf granulocyte macrophage colony-stimulating factor,myeloid progenitor cells
R-21 T-12 T-9 ThemeOf interleukin (IL)-3,hypersensitivity
R-22 T-12 T-10 ThemeOf interleukin (IL)-3,myeloid progenitor cells
R-23 T-14 T-16 CauseOf GOF,induce
R-24 T-15 T-13 CauseOf mutations,gain-of-function
R-25 T-15 T-16 CauseOf mutations,induce
R-26 T-17 T-16 ThemeOf hematopoietic malignancies,induce
R-27 T-18 T-19 ThemeOf SHP-2,plays
R-28 T-20 T-19 ThemeOf IL-3,plays
R-29 T-21 T-22 CauseOf overexpression,attenuates
R-3 T-1 T-0 ThemeOf SHP-2,Mutations
R-30 T-21 T-25 CauseOf overexpression,accelerated
R-31 T-23 T-22 ThemeOf IL-3-mediated,attenuates
R-32 T-24 T-23 ThemeOf hematopoietic cell function,IL-3-mediated
R-33 T-24 T-22 ThemeOf hematopoietic cell function,attenuates
R-34 T-26 T-25 ThemeOf dephosphorylation,accelerated
R-35 T-27 T-26 ThemeOf STAT5,dephosphorylation
R-36 T-27 T-25 ThemeOf STAT5,accelerated
R-37 T-28 T-29 ThemeOf leukemias,attributed
R-38 T-28 T-30 ThemeOf leukemias,increased
R-39 T-31 T-30 ThemeOf catalytic activity,increased
R-4 T-4 T-3 ThemeOf catalytic activity,hyperactivation
R-40 T-31 T-32 ThemeOf catalytic activity,GOF
R-41 T-33 T-30 CauseOf mutant,increased
R-42 T-33 T-32 CauseOf mutant,GOF
R-43 T-33 T-35 CauseOf mutant,GOF
R-44 T-33 T-37 CauseOf mutant,gained
R-45 T-34 T-31 ThemeOf SHP-2,catalytic activity
R-46 T-34 T-33 ThemeOf SHP-2,mutant
R-47 T-35 T-37 CauseOf GOF,gained
R-48 T-36 T-38 ThemeOf SHP-2,capacities
R-49 T-38 T-37 ThemeOf capacities,gained
R-5 T-4 T-5 ThemeOf catalytic activity,identified
R-50 T-39 T-40 ThemeOf effects,GOF
R-51 T-41 T-40 CauseOf mutation,GOF
R-52 T-42 T-39 ThemeOf SHP-2,effects
R-53 T-42 T-41 ThemeOf SHP-2,mutation
R-54 T-43 T-39 ThemeOf hematopoietic cell function,effects
R-55 T-43 T-40 ThemeOf hematopoietic cell function,GOF
R-56 T-46 T-47 CauseOf E76K mutation,caused
R-57 T-46 T-49 CauseOf E76K mutation,decreased
R-58 T-48 T-47 ThemeOf myeloproliferative disease,caused
R-59 T-50 T-49 ThemeOf hematopoietic potential,decreased
R-6 T-6 T-3 ThemeOf leukemias,hyperactivation
R-60 T-51 T-52 CauseOf E76K mutation,increased
R-61 T-51 T-59 CauseOf E76K mutation,leading
R-62 T-51 T-60 CauseOf E76K mutation,hyperactivation
R-63 T-53 T-52 ThemeOf interactions,increased
R-64 T-54 T-53 ThemeOf mutant,interactions
R-65 T-54 T-59 CauseOf mutant,leading
R-66 T-54 T-60 CauseOf mutant,hyperactivation
R-67 T-55 T-53 ThemeOf SHP-2,interactions
R-68 T-55 T-54 ThemeOf SHP-2,mutant
R-69 T-56 T-53 ThemeOf Grb2,interactions
R-7 T-6 T-5 ThemeOf leukemias,identified
R-70 T-56 T-54 ThemeOf Grb2,mutant
R-71 T-57 T-53 ThemeOf Gab2,interactions
R-72 T-57 T-54 ThemeOf Gab2,mutant
R-73 T-58 T-53 ThemeOf p85,interactions
R-74 T-58 T-54 ThemeOf p85,mutant
R-75 T-61 T-60 ThemeOf phosphatidylinositol 3-kinase (PI3K) pathways,hyperactivation
R-76 T-63 T-62 ThemeOf catalytic activity,increase
R-77 T-64 T-62 ThemeOf dephosphorylation,increase
R-78 T-65 T-64 ThemeOf STAT5,dephosphorylation
R-79 T-64 T-68 ThemeOf dephosphorylation,dampened
R-8 T-6 T-8 ThemeOf leukemias,characterized
R-80 T-65 T-67 ThemeOf STAT5,E76K
R-81 T-66 T-64 ThemeOf SHP-2,dephosphorylation
R-82 T-66 T-67 ThemeOf SHP-2,E76K
R-83 T-67 T-62 CauseOf E76K,increase
R-84 T-67 T-68 CauseOf E76K,dampened
R-85 T-69 T-70 ThemeOf SHP-2,C459S mutation
R-86 T-70 T-71 CauseOf C459S mutation,increase
R-87 T-70 T-74 CauseOf C459S mutation,enhance
R-88 T-72 T-71 ThemeOf interaction,increase
R-89 T-73 T-72 ThemeOf Gab2,interaction
R-9 T-6 T-9 ThemeOf leukemias,hypersensitivity
R-90 T-75 T-74 ThemeOf PI3K pathway,enhance
R-91 T-77 T-76 ThemeOf catalytic activity,elevated
R-92 T-79 T-78 ThemeOf interactions,changes
R-93 T-79 T-80 ThemeOf interactions,GOF
R-94 T-81 T-79 ThemeOf SHP-2,interactions
R-95 T-83 T-82 ThemeOf role,play