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PubMed 24373920 Mutant p53 gain of function can be at the root of dedifferentiation of human osteosarcoma MG63 cells into 3AB-OS cancer stem cells. Osteosarcoma is a highly metastatic tumor affecting adolescents, for 2.11 KB 2019-09-23 36 228
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PubMed 24603336 Unequal prognostic potentials of p53 gain-of-function mutations in human cancers associate with drug-metabolizing activity. Mutation of p53 is the most common genetic change in human cancer, causing c 1.49 KB 2019-09-23 35 81
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PubMed 24632946 Disruption of the temporally regulated cloaca endodermal β-catenin signaling causes anorectal malformations. The cloaca is temporally formed and eventually divided by the urorectal septum (URS) during 2.11 KB 2019-09-23 56 134
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PubMed 24632949 Dysregulation of Wnt inhibitory factor 1 (Wif1) expression resulted in aberrant Wnt-β-catenin signaling and cell death of the cloaca endoderm, and anorectal malformations. In mammalian urorectal devel 2 KB 2019-09-23 33 149
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PubMed 24639174 RNA-protein interactions: an overview. RNA binding proteins (RBPs) are key players in the regulation of gene expression. In this chapter we discuss the main protein-RNA recognition modes used by RBPs 1 KB 2017-02-09 2 5
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PubMed 24730569 Significance of the melanocortin 1 receptor in the DNA damage response of human melanocytes to ultraviolet radiation. Activation of the melanocortin 1 receptor (MC1R) by α-melanocortin (α-MSH) stimula 1.15 KB 2019-09-23 32 67
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PubMed 24808909 Assessing the functional consequence of loss of function variants using electronic medical record and large-scale genomics consortium efforts. Estimates from large scale genome sequencing studies indi 898 Bytes 2019-09-23 33 17
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PubMed 24946076 PDGF, pericytes and the pathogenesis of idiopathic basal ganglia calcification (IBGC). Platelet-derived growth factors (PDGFs) are important mitogens for various types of mesenchymal cells, and as suc 1.18 KB 2019-09-23 33 55
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PubMed 25157153 Rare variants in PPARG with decreased activity in adipocyte differentiation are associated with increased risk of type 2 diabetes. Peroxisome proliferator-activated receptor gamma (PPARG) is a master 1.61 KB 2019-09-23 35 85
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PubMed 25220675 tRNA fragments in human health and disease. Transfer RNA (tRNA) is traditionally considered to be an adaptor molecule that helps ribosomes to decode messenger RNA (mRNA) and synthesize protein. Recent 565 Bytes 2020-12-03 2 1
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