Id |
Subject |
Object |
Predicate |
Lexical cue |
TextSentencer_T1 |
0-170 |
Sentence |
denotes |
Transbilayer movement of Glc-P-dolichol and its function as a glucosyl donor: protein-mediated transport of a water-soluble analog into sealed ER vesicles from pig brain. |
T1 |
0-170 |
Sentence |
denotes |
Transbilayer movement of Glc-P-dolichol and its function as a glucosyl donor: protein-mediated transport of a water-soluble analog into sealed ER vesicles from pig brain. |
T1 |
0-170 |
Sentence |
denotes |
Transbilayer movement of Glc-P-dolichol and its function as a glucosyl donor: protein-mediated transport of a water-soluble analog into sealed ER vesicles from pig brain. |
TextSentencer_T2 |
171-477 |
Sentence |
denotes |
The results described in the accompanying article support the model in which glucosylphosphoryldolichol (Glc-P-Dol) is synthesized on the cytoplasmic face of the ER, and functions as a glucosyl donor for three Glc-P-Dol:Glc0-2Man9-GlcNAc2-P-P-Dol glucosyltransferases (GlcTases) in the lumenal compartment. |
T2 |
171-477 |
Sentence |
denotes |
The results described in the accompanying article support the model in which glucosylphosphoryldolichol (Glc-P-Dol) is synthesized on the cytoplasmic face of the ER, and functions as a glucosyl donor for three Glc-P-Dol:Glc0-2Man9-GlcNAc2-P-P-Dol glucosyltransferases (GlcTases) in the lumenal compartment. |
T2 |
171-477 |
Sentence |
denotes |
The results described in the accompanying article support the model in which glucosylphosphoryldolichol (Glc-P-Dol) is synthesized on the cytoplasmic face of the ER, and functions as a glucosyl donor for three Glc-P-Dol:Glc0-2Man9-GlcNAc2-P-P-Dol glucosyltransferases (GlcTases) in the lumenal compartment. |
TextSentencer_T3 |
478-778 |
Sentence |
denotes |
In this study, the enzymatic synthesis and structural characterization by NMR and electrospray-ionization tandem mass spectrometry of a series of water-soluble beta-Glc-P-Dol analogs containing 2-4 isoprene units with either the cis - or trans -stereoconfiguration in the beta-position are described. |
T3 |
478-778 |
Sentence |
denotes |
In this study, the enzymatic synthesis and structural characterization by NMR and electrospray-ionization tandem mass spectrometry of a series of water-soluble beta-Glc-P-Dol analogs containing 2-4 isoprene units with either the cis - or trans -stereoconfiguration in the beta-position are described. |
T3 |
478-778 |
Sentence |
denotes |
In this study, the enzymatic synthesis and structural characterization by NMR and electrospray-ionization tandem mass spectrometry of a series of water-soluble beta-Glc-P-Dol analogs containing 2-4 isoprene units with either the cis - or trans -stereoconfiguration in the beta-position are described. |
TextSentencer_T4 |
779-1092 |
Sentence |
denotes |
The water-soluble analogs were (1) used to examine the stereospecificity of the Glc-P-Dol:Glc0-2Man9GlcNAc2-P-P-Dol glucosyltransferases (GlcTases) and (2) tested as potential substrates for a membrane protein(s) mediating the transbilayer movement of Glc-P-Dol in sealed ER vesicles from rat liver and pig brain. |
T4 |
779-1092 |
Sentence |
denotes |
The water-soluble analogs were (1) used to examine the stereospecificity of the Glc-P-Dol:Glc0-2Man9GlcNAc2-P-P-Dol glucosyltransferases (GlcTases) and (2) tested as potential substrates for a membrane protein(s) mediating the transbilayer movement of Glc-P-Dol in sealed ER vesicles from rat liver and pig brain. |
T4 |
779-1092 |
Sentence |
denotes |
The water-soluble analogs were (1) used to examine the stereospecificity of the Glc-P-Dol:Glc0-2Man9GlcNAc2-P-P-Dol glucosyltransferases (GlcTases) and (2) tested as potential substrates for a membrane protein(s) mediating the transbilayer movement of Glc-P-Dol in sealed ER vesicles from rat liver and pig brain. |
TextSentencer_T5 |
1093-1351 |
Sentence |
denotes |
The Glc-P-Dol-mediated GlcTases in pig brain microsomes utilized [3H]Glc-labeled Glc-P-Dol10, Glc-P-(omega, c )Dol15, Glc-P(omega, t,t )Dol20, and Glc-P-(omega, t,c )Dol20as glucosyl donors with [3H]Glc3Man9GlcNAc2-P-P-Dol the major product labeled in vitro. |
T5 |
1093-1351 |
Sentence |
denotes |
The Glc-P-Dol-mediated GlcTases in pig brain microsomes utilized [3H]Glc-labeled Glc-P-Dol10, Glc-P-(omega, c )Dol15, Glc-P(omega, t,t )Dol20, and Glc-P-(omega, t,c )Dol20as glucosyl donors with [3H]Glc3Man9GlcNAc2-P-P-Dol the major product labeled in vitro. |
T5 |
1093-1351 |
Sentence |
denotes |
The Glc-P-Dol-mediated GlcTases in pig brain microsomes utilized [3H]Glc-labeled Glc-P-Dol10, Glc-P-(omega, c )Dol15, Glc-P(omega, t,t )Dol20, and Glc-P-(omega, t,c )Dol20as glucosyl donors with [3H]Glc3Man9GlcNAc2-P-P-Dol the major product labeled in vitro. |
TextSentencer_T6 |
1352-1464 |
Sentence |
denotes |
A preference was exhibited for C15-20 substrates containing an internal cis -isoprene unit in the beta-position. |
T6 |
1352-1464 |
Sentence |
denotes |
A preference was exhibited for C15-20 substrates containing an internal cis -isoprene unit in the beta-position. |
T6 |
1352-1464 |
Sentence |
denotes |
A preference was exhibited for C15-20 substrates containing an internal cis -isoprene unit in the beta-position. |
TextSentencer_T7 |
1465-1678 |
Sentence |
denotes |
In addition, the water-soluble analog, Glc-P-Dol10, was shown to enter the lumenal compartment of sealed microsomal vesicles from rat liver and pig brain via a protein-mediated transport system enriched in the ER. |
T7 |
1465-1678 |
Sentence |
denotes |
In addition, the water-soluble analog, Glc-P-Dol10, was shown to enter the lumenal compartment of sealed microsomal vesicles from rat liver and pig brain via a protein-mediated transport system enriched in the ER. |
T7 |
1465-1678 |
Sentence |
denotes |
In addition, the water-soluble analog, Glc-P-Dol10, was shown to enter the lumenal compartment of sealed microsomal vesicles from rat liver and pig brain via a protein-mediated transport system enriched in the ER. |
TextSentencer_T8 |
1679-1745 |
Sentence |
denotes |
The properties of the ER transport system have been characterized. |
T8 |
1679-1745 |
Sentence |
denotes |
The properties of the ER transport system have been characterized. |
T8 |
1679-1745 |
Sentence |
denotes |
The properties of the ER transport system have been characterized. |
TextSentencer_T9 |
1746-1843 |
Sentence |
denotes |
Glc-P-Dol10was not transported into or adsorbed by synthetic PC-liposomes or bovine erythrocytes. |
T9 |
1746-1843 |
Sentence |
denotes |
Glc-P-Dol10was not transported into or adsorbed by synthetic PC-liposomes or bovine erythrocytes. |
T9 |
1746-1843 |
Sentence |
denotes |
Glc-P-Dol10was not transported into or adsorbed by synthetic PC-liposomes or bovine erythrocytes. |
TextSentencer_T10 |
1844-2235 |
Sentence |
denotes |
The results of these studies indicate that (1) the internal cis -isoprene units are important for the utilization of Glc-P-Dol as a glucosyl donor and (2) the transport of the water-soluble analog may provide an experimental approach to assay the hypothetical "flippase" proposed to mediate the transbilayer movement of Glc-P-Dol from the cytoplasmic face of the ER to the lumenal monolayer. |
T10 |
1844-2235 |
Sentence |
denotes |
The results of these studies indicate that (1) the internal cis -isoprene units are important for the utilization of Glc-P-Dol as a glucosyl donor and (2) the transport of the water-soluble analog may provide an experimental approach to assay the hypothetical "flippase" proposed to mediate the transbilayer movement of Glc-P-Dol from the cytoplasmic face of the ER to the lumenal monolayer. |
T10 |
1844-2235 |
Sentence |
denotes |
The results of these studies indicate that (1) the internal cis -isoprene units are important for the utilization of Glc-P-Dol as a glucosyl donor and (2) the transport of the water-soluble analog may provide an experimental approach to assay the hypothetical "flippase" proposed to mediate the transbilayer movement of Glc-P-Dol from the cytoplasmic face of the ER to the lumenal monolayer. |