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PubMed:9858225 JSONTXT 11 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-134 Sentence denotes Systemic mastocytosis associated with acute myeloid leukaemia: report of two cases and detection of the c-kit mutation Asp-816 to Val.
T1 0-134 Sentence denotes Systemic mastocytosis associated with acute myeloid leukaemia: report of two cases and detection of the c-kit mutation Asp-816 to Val.
TextSentencer_T2 135-226 Sentence denotes A subset of patients with systemic mastocytosis (SM) develop acute myeloid leukaemia (AML).
T2 135-226 Sentence denotes A subset of patients with systemic mastocytosis (SM) develop acute myeloid leukaemia (AML).
TextSentencer_T3 227-342 Sentence denotes However, little is known about the biology of such leukaemias and their relationship to the mast cell (MC) lineage.
T3 227-342 Sentence denotes However, little is known about the biology of such leukaemias and their relationship to the mast cell (MC) lineage.
TextSentencer_T4 343-405 Sentence denotes We report on two female patients who suffered from SM and AML.
T4 343-405 Sentence denotes We report on two female patients who suffered from SM and AML.
TextSentencer_T5 406-509 Sentence denotes According to FAB criteria, the leukaemias were classified as AML-M4 (patient 1) and AML-MO (patient 2).
T5 406-509 Sentence denotes According to FAB criteria, the leukaemias were classified as AML-M4 (patient 1) and AML-MO (patient 2).
TextSentencer_T6 510-673 Sentence denotes The coexistence of the two distinct neoplasms (AML and SM) was demonstrable by immunostaining of serial bone marrow (BM) sections with monoclonal antibodies (mAb).
T6 510-673 Sentence denotes The coexistence of the two distinct neoplasms (AML and SM) was demonstrable by immunostaining of serial bone marrow (BM) sections with monoclonal antibodies (mAb).
TextSentencer_T7 674-835 Sentence denotes In particular, the MC infiltrates were found to react with mAb against MC-tryptase and MC growth factor receptor c-kit (CD117), but not with mAb to CD15 or CD34.
T7 674-835 Sentence denotes In particular, the MC infiltrates were found to react with mAb against MC-tryptase and MC growth factor receptor c-kit (CD117), but not with mAb to CD15 or CD34.
TextSentencer_T8 836-955 Sentence denotes In contrast, the AML blasts were immunoreactive for CD15 (patient 1) or CD34 (patient 2), but did not express tryptase.
T8 836-955 Sentence denotes In contrast, the AML blasts were immunoreactive for CD15 (patient 1) or CD34 (patient 2), but did not express tryptase.
TextSentencer_T9 956-1137 Sentence denotes The c-kit point mutation Asp-->Val at codon 816, considered to play a role in the transformation of MC progenitors, was detected in patient 1 in a BM cell fraction containing 4% MC.
T9 956-1137 Sentence denotes The c-kit point mutation Asp-->Val at codon 816, considered to play a role in the transformation of MC progenitors, was detected in patient 1 in a BM cell fraction containing 4% MC.
TextSentencer_T10 1138-1203 Sentence denotes However, no c-kit mutation was found in pure AML blasts (<1% MC).
T10 1138-1203 Sentence denotes However, no c-kit mutation was found in pure AML blasts (<1% MC).
TextSentencer_T11 1204-1310 Sentence denotes These findings argue against an evolution of the AML clone from neoplastic MC or MC-committed progenitors.
T11 1204-1310 Sentence denotes These findings argue against an evolution of the AML clone from neoplastic MC or MC-committed progenitors.