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Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-112 Sentence denotes Activation of ErbB4 by the bifunctional epidermal growth factor family hormone epiregulin is regulated by ErbB2.
T1 0-112 Sentence denotes Activation of ErbB4 by the bifunctional epidermal growth factor family hormone epiregulin is regulated by ErbB2.
TextSentencer_T2 113-231 Sentence denotes Epiregulin (EPR) is a recently described member of the epidermal growth factor (EGF) family of peptide growth factors.
T2 113-231 Sentence denotes Epiregulin (EPR) is a recently described member of the epidermal growth factor (EGF) family of peptide growth factors.
TextSentencer_T3 232-341 Sentence denotes The ever expanding size of the EGF family has made distinguishing the activities of these hormones paramount.
T3 232-341 Sentence denotes The ever expanding size of the EGF family has made distinguishing the activities of these hormones paramount.
TextSentencer_T4 342-485 Sentence denotes We show here that EPR activates two members of the ErbB family of receptor tyrosine kinases, epidermal growth factor receptor (EGFR) and ErbB4.
T4 342-485 Sentence denotes We show here that EPR activates two members of the ErbB family of receptor tyrosine kinases, epidermal growth factor receptor (EGFR) and ErbB4.
TextSentencer_T5 486-594 Sentence denotes Therefore by these criteria, EPR is qualitatively similar to another EGF family hormone, betacellulin (BTC).
T5 486-594 Sentence denotes Therefore by these criteria, EPR is qualitatively similar to another EGF family hormone, betacellulin (BTC).
TextSentencer_T6 595-670 Sentence denotes Yet, here we also demonstrate quantitative differences between EPR and BTC.
T6 595-670 Sentence denotes Yet, here we also demonstrate quantitative differences between EPR and BTC.
TextSentencer_T7 671-815 Sentence denotes EPR stimulates higher levels of EGFR phosphorylation than does BTC, whereas BTC stimulates higher levels of ErbB4 phosphorylation than does EPR.
T7 671-815 Sentence denotes EPR stimulates higher levels of EGFR phosphorylation than does BTC, whereas BTC stimulates higher levels of ErbB4 phosphorylation than does EPR.
TextSentencer_T8 816-971 Sentence denotes Moreover, the EPR and BTC dose response curves show that although EGFR is more sensitive to EPR than is ErbB4, ErbB4 is more sensitive to BTC than is EGFR.
T8 816-971 Sentence denotes Moreover, the EPR and BTC dose response curves show that although EGFR is more sensitive to EPR than is ErbB4, ErbB4 is more sensitive to BTC than is EGFR.
TextSentencer_T9 972-1102 Sentence denotes Finally, ErbB2, which is not activated by EPR when expressed on its own, increases the sensitivity of ErbB4 for activation by EPR.
T9 972-1102 Sentence denotes Finally, ErbB2, which is not activated by EPR when expressed on its own, increases the sensitivity of ErbB4 for activation by EPR.
TextSentencer_T10 1103-1263 Sentence denotes Therefore, these results establish that EPR exhibits novel activities and modes of regulation, which may have significant implications for EPR function in vivo.
T10 1103-1263 Sentence denotes Therefore, these results establish that EPR exhibits novel activities and modes of regulation, which may have significant implications for EPR function in vivo.