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PubMed:9508061 JSONTXT 6 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-54 Sentence denotes Apolipoprotein E allelic frequency in elderly smokers.
T1 0-54 Sentence denotes Apolipoprotein E allelic frequency in elderly smokers.
TextSentencer_T2 55-267 Sentence denotes Susceptibility genes for human diseases (e.g., cancer and atherosclerosis) increase disease risk by altering the metabolic activation of exogenous (e.g., carcinogens) and endogenous (e.g., cholesterol) compounds.
T2 55-267 Sentence denotes Susceptibility genes for human diseases (e.g., cancer and atherosclerosis) increase disease risk by altering the metabolic activation of exogenous (e.g., carcinogens) and endogenous (e.g., cholesterol) compounds.
TextSentencer_T3 268-361 Sentence denotes The function of these genes, and subsequent risk, can be adversely affected by polymorphisms.
T3 268-361 Sentence denotes The function of these genes, and subsequent risk, can be adversely affected by polymorphisms.
TextSentencer_T4 362-625 Sentence denotes This study tests the hypothesis that if specific genetic polymorphisms are related to mortality, then in elderly heavy smokers, there should be a decreased frequency of "at risk" alleles and an increased frequency of "protective" alleles, i.e., a survival effect.
T4 362-625 Sentence denotes This study tests the hypothesis that if specific genetic polymorphisms are related to mortality, then in elderly heavy smokers, there should be a decreased frequency of "at risk" alleles and an increased frequency of "protective" alleles, i.e., a survival effect.
TextSentencer_T5 626-881 Sentence denotes One such potential polymorphism is in the apolipoprotein E (apoE) gene, which is involved in cholesterol metabolism, where the epsilon4 allele is associated with an increased risk of coronary artery disease and is under represented in elderly populations.
T5 626-881 Sentence denotes One such potential polymorphism is in the apolipoprotein E (apoE) gene, which is involved in cholesterol metabolism, where the epsilon4 allele is associated with an increased risk of coronary artery disease and is under represented in elderly populations.
TextSentencer_T6 882-982 Sentence denotes In this study, ApoE variant alleles were determined in 81 living, elderly current smokers (mean age:
T6 882-982 Sentence denotes In this study, ApoE variant alleles were determined in 81 living, elderly current smokers (mean age:
TextSentencer_T7 983-995 Sentence denotes 72.5; range:
T7 983-995 Sentence denotes 72.5; range:
TextSentencer_T8 996-1019 Sentence denotes 65-94; mean pack-years:
T8 996-1019 Sentence denotes 65-94; mean pack-years:
TextSentencer_T9 1020-1030 Sentence denotes 78; range:
T9 1020-1030 Sentence denotes 78; range:
TextSentencer_T10 1031-1082 Sentence denotes 13-192) and in 82 younger autopsy donors (mean age:
T10 1031-1082 Sentence denotes 13-192) and in 82 younger autopsy donors (mean age:
TextSentencer_T11 1083-1093 Sentence denotes 33; range:
T11 1083-1093 Sentence denotes 33; range:
TextSentencer_T12 1094-1100 Sentence denotes 1-58).
T12 1094-1100 Sentence denotes 1-58).
TextSentencer_T13 1101-1281 Sentence denotes There was a borderline difference in the apoE 4 allelic frequencies among the groups (11% in the elderly and 18% in the comparable younger group [df = 1; chi(2) = 4.02; P = 0.05]).
T13 1101-1281 Sentence denotes There was a borderline difference in the apoE 4 allelic frequencies among the groups (11% in the elderly and 18% in the comparable younger group [df = 1; chi(2) = 4.02; P = 0.05]).
TextSentencer_T14 1282-1492 Sentence denotes A significant difference was found for age when stratified as a continuous variable by genotype in the elderly smokers (P = 0.03; mean age for persons with and without epsilon4 was 69.9 and 73.2, respectively).
T14 1282-1492 Sentence denotes A significant difference was found for age when stratified as a continuous variable by genotype in the elderly smokers (P = 0.03; mean age for persons with and without epsilon4 was 69.9 and 73.2, respectively).
TextSentencer_T15 1493-1584 Sentence denotes Pack-years of cigarette smokers did not differ by genotype, indicating no selective effect.
T15 1493-1584 Sentence denotes Pack-years of cigarette smokers did not differ by genotype, indicating no selective effect.
TextSentencer_T16 1585-1772 Sentence denotes These results confirm earlier associations for differences in the apoE allelic frequencies in the elderly and extend it to smokers, who generally have increased mortality at younger ages.
T16 1585-1772 Sentence denotes These results confirm earlier associations for differences in the apoE allelic frequencies in the elderly and extend it to smokers, who generally have increased mortality at younger ages.