> top > projects > sentences > docs > PubMed:9360945 > annotations
sentences Home  

PubMed:9360945 JSONTXT 30 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
T1 0-100 Sentence denotes Transcription factor NF-kappaB regulates inducible Oct-2 gene expression in precursor B lymphocytes.
T1 0-100 Sentence denotes Transcription factor NF-kappaB regulates inducible Oct-2 gene expression in precursor B lymphocytes.
T2 101-280 Sentence denotes The POU transcription factors Oct-1 and Oct-2 regulate the activity of octamer-dependent promoters, including those that direct transcription from rearranged immunoglobulin genes.
T2 101-280 Sentence denotes The POU transcription factors Oct-1 and Oct-2 regulate the activity of octamer-dependent promoters, including those that direct transcription from rearranged immunoglobulin genes.
T3 281-502 Sentence denotes Unlike Oct-1, which is constitutively expressed in many cell types, Oct-2 expression is restricted primarily to B lymphocytes and can be induced in precursor B cells by stimulation with bacterial lipopolysaccharide (LPS).
T3 281-502 Sentence denotes Unlike Oct-1, which is constitutively expressed in many cell types, Oct-2 expression is restricted primarily to B lymphocytes and can be induced in precursor B cells by stimulation with bacterial lipopolysaccharide (LPS).
T4 503-585 Sentence denotes However, the precise factors that mediate this induction mechanism remain unknown.
T4 503-585 Sentence denotes However, the precise factors that mediate this induction mechanism remain unknown.
T5 586-753 Sentence denotes In the present study, we monitored Oct-2 expression in cells arrested for the activation of NF-kappaB, an LPS-responsive member of the Rel transcription factor family.
T5 586-753 Sentence denotes In the present study, we monitored Oct-2 expression in cells arrested for the activation of NF-kappaB, an LPS-responsive member of the Rel transcription factor family.
T6 754-976 Sentence denotes Despite stimulation with LPS, disruption of the NF-kappaB signaling pathway in precursor B cells led to the loss of inducible Oct-2 DNA binding activity in vitro and the suppression of Oct-2-directed transcription in vivo.
T6 754-976 Sentence denotes Despite stimulation with LPS, disruption of the NF-kappaB signaling pathway in precursor B cells led to the loss of inducible Oct-2 DNA binding activity in vitro and the suppression of Oct-2-directed transcription in vivo.
T7 977-1137 Sentence denotes This biochemical defect correlated with a specific block to Oct-2 gene expression at the level of transcription, whereas the expression of Oct-1 was unaffected.
T7 977-1137 Sentence denotes This biochemical defect correlated with a specific block to Oct-2 gene expression at the level of transcription, whereas the expression of Oct-1 was unaffected.
T8 1138-1322 Sentence denotes The finding that Oct-2 is under NF-kappaB control highlights an important cross-talk mechanism involving two distinct transcription factor families that regulate B lymphocyte function.
T8 1138-1322 Sentence denotes The finding that Oct-2 is under NF-kappaB control highlights an important cross-talk mechanism involving two distinct transcription factor families that regulate B lymphocyte function.