| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T1 |
0-103 |
Sentence |
denotes |
Association of hemoglobin Saint Etienne (alpha2beta295F8 His replaced by G1n) with hemoglobins A and F. |
| T1 |
0-103 |
Sentence |
denotes |
Association of hemoglobin Saint Etienne (alpha2beta295F8 His replaced by G1n) with hemoglobins A and F. |
| T2 |
104-144 |
Sentence |
denotes |
Synthesis and subunit exchange in vitro. |
| T2 |
104-144 |
Sentence |
denotes |
Synthesis and subunit exchange in vitro. |
| T3 |
145-289 |
Sentence |
denotes |
The unstable hemoglobin (Hb) Saint Etienne (alpha2beta295F8 His replaced by G1n) (betaSE) was found in the red blood cells of an 8-year-old boy. |
| T3 |
145-289 |
Sentence |
denotes |
The unstable hemoglobin (Hb) Saint Etienne (alpha2beta295F8 His replaced by G1n) (betaSE) was found in the red blood cells of an 8-year-old boy. |
| T4 |
290-373 |
Sentence |
denotes |
The composition of this hemoglobin was 26% Saint Etienne, 52% A, 3% A2 and 19% HbF. |
| T4 |
290-373 |
Sentence |
denotes |
The composition of this hemoglobin was 26% Saint Etienne, 52% A, 3% A2 and 19% HbF. |
| T5 |
374-623 |
Sentence |
denotes |
Studies of hemoglobin synthesis indicate: a) a balanced synthesis of alpha and non-alpha chains (alpha=betaA + betaSE + gamma), b) an increased pool of free alpha hemoglobin chains, and c) a rapid exchange of alpha chains between this pool and HbSE. |
| T5 |
374-623 |
Sentence |
denotes |
Studies of hemoglobin synthesis indicate: a) a balanced synthesis of alpha and non-alpha chains (alpha=betaA + betaSE + gamma), b) an increased pool of free alpha hemoglobin chains, and c) a rapid exchange of alpha chains between this pool and HbSE. |
| T6 |
624-760 |
Sentence |
denotes |
The alpha chain pool resulted from the dissociation of HbSE and the greater instability of betaSE chains than alpha chains upon heating. |
| T6 |
624-760 |
Sentence |
denotes |
The alpha chain pool resulted from the dissociation of HbSE and the greater instability of betaSE chains than alpha chains upon heating. |
| T7 |
761-850 |
Sentence |
denotes |
Hemoglobin F is of the fetal type and is heterogeneously distributed among the red cells. |
| T7 |
761-850 |
Sentence |
denotes |
Hemoglobin F is of the fetal type and is heterogeneously distributed among the red cells. |
| T8 |
851-955 |
Sentence |
denotes |
Furthermore, two populations of red blood cells could be separated according to their i antigen content. |
| T8 |
851-955 |
Sentence |
denotes |
Furthermore, two populations of red blood cells could be separated according to their i antigen content. |
| T9 |
956-1022 |
Sentence |
denotes |
Analysis of the hemoglobins revealed a heterogeneous distribution. |
| T9 |
956-1022 |
Sentence |
denotes |
Analysis of the hemoglobins revealed a heterogeneous distribution. |
| T10 |
1023-1195 |
Sentence |
denotes |
Thus, F hemoglobin was preferentially associated with cells having low i antigen level, while Saint Etienne hemoglobin was increased in cells having a high i antigen level. |
| T10 |
1023-1195 |
Sentence |
denotes |
Thus, F hemoglobin was preferentially associated with cells having low i antigen level, while Saint Etienne hemoglobin was increased in cells having a high i antigen level. |
| T11 |
1196-1259 |
Sentence |
denotes |
HbF and HbSE were not present in the parents of the propositus. |
| T11 |
1196-1259 |
Sentence |
denotes |
HbF and HbSE were not present in the parents of the propositus. |
| T12 |
1260-1313 |
Sentence |
denotes |
Study of the genetic markers confirmed the filiation. |
| T12 |
1260-1313 |
Sentence |
denotes |
Study of the genetic markers confirmed the filiation. |
| T13 |
1314-1443 |
Sentence |
denotes |
The parents were normal upon clinical and hematological examination; they exhibited a normal pattern and synthesis of hemoglobin. |
| T13 |
1314-1443 |
Sentence |
denotes |
The parents were normal upon clinical and hematological examination; they exhibited a normal pattern and synthesis of hemoglobin. |
| T14 |
1444-1594 |
Sentence |
denotes |
The Hb Saint Etienne case is compared with Hb Istanbul, which in spite of the same amino acid substitution is not associated with increased HbF level. |
| T14 |
1444-1594 |
Sentence |
denotes |
The Hb Saint Etienne case is compared with Hb Istanbul, which in spite of the same amino acid substitution is not associated with increased HbF level. |