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PubMed:9206974 JSONTXT 6 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-60 Sentence denotes Genes implicated in the pathogenesis of Alzheimer's disease.
T1 0-60 Sentence denotes Genes implicated in the pathogenesis of Alzheimer's disease.
TextSentencer_T2 61-158 Sentence denotes Both the early and late-onset Alzheimer's disease affect millions of people throughout the world.
T2 61-158 Sentence denotes Both the early and late-onset Alzheimer's disease affect millions of people throughout the world.
TextSentencer_T3 159-245 Sentence denotes A number of molecules have been implicated in the pathogenesis of Alzheimer's disease.
T3 159-245 Sentence denotes A number of molecules have been implicated in the pathogenesis of Alzheimer's disease.
TextSentencer_T4 246-334 Sentence denotes These include presenilin 1 and 2 (PS1 and PS2), a beta-amyloid peptide, and tau protein.
T4 246-334 Sentence denotes These include presenilin 1 and 2 (PS1 and PS2), a beta-amyloid peptide, and tau protein.
TextSentencer_T5 335-436 Sentence denotes Presenilin 1 and 2 genes implicated in the early-onset familial Alzheimer's disease have been cloned.
T5 335-436 Sentence denotes Presenilin 1 and 2 genes implicated in the early-onset familial Alzheimer's disease have been cloned.
TextSentencer_T6 437-535 Sentence denotes Both PS1 and PS2 are integral membrane proteins and may function as receptors or channel proteins.
T6 437-535 Sentence denotes Both PS1 and PS2 are integral membrane proteins and may function as receptors or channel proteins.
TextSentencer_T7 536-658 Sentence denotes Missense mutations in PS1 and PS2 genes have been found in families that cosegregate with early-onset Alzheimer's disease.
T7 536-658 Sentence denotes Missense mutations in PS1 and PS2 genes have been found in families that cosegregate with early-onset Alzheimer's disease.
TextSentencer_T8 659-755 Sentence denotes Overexpression of the mutated PS1 gene produced amyloid plaques in the brain of transgenic mice.
T8 659-755 Sentence denotes Overexpression of the mutated PS1 gene produced amyloid plaques in the brain of transgenic mice.
TextSentencer_T9 756-932 Sentence denotes Secreted beta-amyloid protein similar to that in the senile plaques of Alzheimer's disease was found to be elevated in fibroblast media from subjects with PS1 or PS2 mutations.
T9 756-932 Sentence denotes Secreted beta-amyloid protein similar to that in the senile plaques of Alzheimer's disease was found to be elevated in fibroblast media from subjects with PS1 or PS2 mutations.
TextSentencer_T10 933-1147 Sentence denotes Transgenic mice which carried the mutant form of the beta-amyloid precursor protein gene expressed high concentrations of mutant copy of the gene and exhibited abundant amyloid plaques in the brain and memory loss.
T10 933-1147 Sentence denotes Transgenic mice which carried the mutant form of the beta-amyloid precursor protein gene expressed high concentrations of mutant copy of the gene and exhibited abundant amyloid plaques in the brain and memory loss.
TextSentencer_T11 1148-1197 Sentence denotes The mutated PS2 gene enhanced apoptotic activity.
T11 1148-1197 Sentence denotes The mutated PS2 gene enhanced apoptotic activity.
TextSentencer_T12 1198-1333 Sentence denotes This enhanced apoptotic activity may accelerate the process of neurodegeneration leading to an earlier age in the onset of the disease.
T12 1198-1333 Sentence denotes This enhanced apoptotic activity may accelerate the process of neurodegeneration leading to an earlier age in the onset of the disease.
TextSentencer_T13 1334-1488 Sentence denotes Identification of lesions in the molecules that are important in the Alzheimer's disease should allow developing therapeutic approaches for its treatment.
T13 1334-1488 Sentence denotes Identification of lesions in the molecules that are important in the Alzheimer's disease should allow developing therapeutic approaches for its treatment.