> top > projects > sentences > docs > PubMed:8999806 > annotations
sentences Home  

PubMed:8999806 JSONTXT 30 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
T1 0-190 Sentence denotes Constitutive dephosphorylation and activation of a member of the nuclear factor of activated T cells, NF-AT1, in Tax-expressing and type I human T-cell leukemia virus-infected human T cells.
T1 0-190 Sentence denotes Constitutive dephosphorylation and activation of a member of the nuclear factor of activated T cells, NF-AT1, in Tax-expressing and type I human T-cell leukemia virus-infected human T cells.
T2 191-378 Sentence denotes The tax gene product of the type I human T-cell leukemia virus (HTLV-I) transactivates interleukin-2 (IL-2) gene through activation of an enhancer termed CD28 responsive element (CD28RE).
T2 191-378 Sentence denotes The tax gene product of the type I human T-cell leukemia virus (HTLV-I) transactivates interleukin-2 (IL-2) gene through activation of an enhancer termed CD28 responsive element (CD28RE).
T3 379-493 Sentence denotes Tax activation of the CD28RE is partially mediated by a member of the nuclear factor of activated T cells, NF-AT1.
T3 379-493 Sentence denotes Tax activation of the CD28RE is partially mediated by a member of the nuclear factor of activated T cells, NF-AT1.
T4 494-715 Sentence denotes We have previously shown that NF-AT1 is constitutively active in Jurkat T cells stably transfected with the Tax cDNA, although the underlying molecular mechanism and physiological relevance of this finding remain unclear.
T4 494-715 Sentence denotes We have previously shown that NF-AT1 is constitutively active in Jurkat T cells stably transfected with the Tax cDNA, although the underlying molecular mechanism and physiological relevance of this finding remain unclear.
T5 716-867 Sentence denotes In this report, we demonstrate that the active form of NF-AT1 is also present in the nuclei of HTLV-I-transformed T cells that express the Tax protein.
T5 716-867 Sentence denotes In this report, we demonstrate that the active form of NF-AT1 is also present in the nuclei of HTLV-I-transformed T cells that express the Tax protein.
T6 868-979 Sentence denotes Interestingly, the constitutive activation of NF-AT1 in these T cells is associated with its dephosphorylation.
T6 868-979 Sentence denotes Interestingly, the constitutive activation of NF-AT1 in these T cells is associated with its dephosphorylation.
T7 980-1179 Sentence denotes Furthermore, the dephosphorylated NF-AT1 can be rapidly rephosphorylated when the cells are incubated with cyclosporin A, an immunosuppressant inhibiting the serine/threonine phosphatase calcineurin.
T7 980-1179 Sentence denotes Furthermore, the dephosphorylated NF-AT1 can be rapidly rephosphorylated when the cells are incubated with cyclosporin A, an immunosuppressant inhibiting the serine/threonine phosphatase calcineurin.
T8 1180-1369 Sentence denotes These results suggest that activation of NF-AT1 in Tax-expressing and HTLV-I-transformed T cells results from its dephosphorylation, which in turn may be due to deregulation of calcineurin.
T8 1180-1369 Sentence denotes These results suggest that activation of NF-AT1 in Tax-expressing and HTLV-I-transformed T cells results from its dephosphorylation, which in turn may be due to deregulation of calcineurin.