| Id |
Subject |
Object |
Predicate |
Lexical cue |
| TextSentencer_T1 |
0-141 |
Sentence |
denotes |
Dentin phosphoprotein and dentin sialoprotein are cleavage products expressed from a single transcript coded by a gene on human chromosome 4. |
| T1 |
0-141 |
Sentence |
denotes |
Dentin phosphoprotein and dentin sialoprotein are cleavage products expressed from a single transcript coded by a gene on human chromosome 4. |
| TextSentencer_T2 |
142-191 |
Sentence |
denotes |
Dentin phosphoprotein DNA sequence determination. |
| T2 |
142-191 |
Sentence |
denotes |
Dentin phosphoprotein DNA sequence determination. |
| TextSentencer_T3 |
192-258 |
Sentence |
denotes |
Dentin is the major mineralized extracellular matrix of the tooth. |
| T3 |
192-258 |
Sentence |
denotes |
Dentin is the major mineralized extracellular matrix of the tooth. |
| TextSentencer_T4 |
259-393 |
Sentence |
denotes |
The organic components of dentin consist of type I collagen (90%) with 10% noncollagenous proteins, which are also components of bone. |
| T4 |
259-393 |
Sentence |
denotes |
The organic components of dentin consist of type I collagen (90%) with 10% noncollagenous proteins, which are also components of bone. |
| TextSentencer_T5 |
394-543 |
Sentence |
denotes |
Two dentin proteins, dentin sialoprotein and dentin phosphoprotein, have been shown to be tooth-specific being expressed mostly by odontoblast cells. |
| T5 |
394-543 |
Sentence |
denotes |
Two dentin proteins, dentin sialoprotein and dentin phosphoprotein, have been shown to be tooth-specific being expressed mostly by odontoblast cells. |
| TextSentencer_T6 |
544-661 |
Sentence |
denotes |
In this study, we screened a mouse molar tooth library for dentin sialoprotein and dentin phosphoprotein cDNA clones. |
| T6 |
544-661 |
Sentence |
denotes |
In this study, we screened a mouse molar tooth library for dentin sialoprotein and dentin phosphoprotein cDNA clones. |
| TextSentencer_T7 |
662-791 |
Sentence |
denotes |
Analysis of the clones resulted in characterization of a 4420-nucleotide cDNA that contained a 940-amino acid open reading frame. |
| T7 |
662-791 |
Sentence |
denotes |
Analysis of the clones resulted in characterization of a 4420-nucleotide cDNA that contained a 940-amino acid open reading frame. |
| TextSentencer_T8 |
792-904 |
Sentence |
denotes |
The signal peptide and NH2-terminal sequence was 75% homologous to the cDNA sequence of rat dentin sialoprotein. |
| T8 |
792-904 |
Sentence |
denotes |
The signal peptide and NH2-terminal sequence was 75% homologous to the cDNA sequence of rat dentin sialoprotein. |
| TextSentencer_T9 |
905-1040 |
Sentence |
denotes |
The continued open reading frame, however, contained a RGD sequence followed by a region of repeated aspartic acid and serine residues. |
| T9 |
905-1040 |
Sentence |
denotes |
The continued open reading frame, however, contained a RGD sequence followed by a region of repeated aspartic acid and serine residues. |
| TextSentencer_T10 |
1041-1145 |
Sentence |
denotes |
This portion of the protein codes for amino acid sequence consistent with that of dentin phosphoprotein. |
| T10 |
1041-1145 |
Sentence |
denotes |
This portion of the protein codes for amino acid sequence consistent with that of dentin phosphoprotein. |
| TextSentencer_T11 |
1146-1256 |
Sentence |
denotes |
The noncoding region contains three potential polyadenylation signals, two of which were shown to be utilized. |
| T11 |
1146-1256 |
Sentence |
denotes |
The noncoding region contains three potential polyadenylation signals, two of which were shown to be utilized. |
| TextSentencer_T12 |
1257-1369 |
Sentence |
denotes |
Northern blot analysis indicated the presence of two major transcripts of 4.4 and 2.2 kilobases in odontoblasts. |
| T12 |
1257-1369 |
Sentence |
denotes |
Northern blot analysis indicated the presence of two major transcripts of 4.4 and 2.2 kilobases in odontoblasts. |
| TextSentencer_T13 |
1370-1431 |
Sentence |
denotes |
Chromosomal mapping localized the gene to human chromosome 4. |
| T13 |
1370-1431 |
Sentence |
denotes |
Chromosomal mapping localized the gene to human chromosome 4. |
| TextSentencer_T14 |
1432-1735 |
Sentence |
denotes |
These data suggest that the previously identified dentin extracellular matrix proteins, dentin sialoprotein and dentin phosphoprotein, are expressed as a single cDNA transcript coding for a protein that is specifically cleaved into two smaller polypeptides with unique physical-chemical characteristics. |
| T14 |
1432-1735 |
Sentence |
denotes |
These data suggest that the previously identified dentin extracellular matrix proteins, dentin sialoprotein and dentin phosphoprotein, are expressed as a single cDNA transcript coding for a protein that is specifically cleaved into two smaller polypeptides with unique physical-chemical characteristics. |
| TextSentencer_T15 |
1736-1808 |
Sentence |
denotes |
Therefore, we propose that the gene be named dentin sialophosphoprotein. |
| T15 |
1736-1808 |
Sentence |
denotes |
Therefore, we propose that the gene be named dentin sialophosphoprotein. |
| TextSentencer_T16 |
1809-1996 |
Sentence |
denotes |
The location of the human dentin sialophosphoprotein gene on chromosome 4 suggests that this gene may be a strong candidate gene for the genetic disease dentinogenesis imperfecta type II. |
| T16 |
1809-1996 |
Sentence |
denotes |
The location of the human dentin sialophosphoprotein gene on chromosome 4 suggests that this gene may be a strong candidate gene for the genetic disease dentinogenesis imperfecta type II. |