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PubMed:8995236 JSONTXT 37 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
T1 0-63 Sentence denotes Mycobacterium smegmatis phosphoinositols-glyceroarabinomannans.
T1 0-63 Sentence denotes Mycobacterium smegmatis phosphoinositols-glyceroarabinomannans.
T2 64-144 Sentence denotes Structure and localization of alkali-labile and alkali-stable phosphoinositides.
T2 64-144 Sentence denotes Structure and localization of alkali-labile and alkali-stable phosphoinositides.
T3 145-269 Sentence denotes Lipoarabinomannans from fast growing Mycobacterium sp., namely AraLAMs, stimulate the early events of macrophage activation.
T3 145-269 Sentence denotes Lipoarabinomannans from fast growing Mycobacterium sp., namely AraLAMs, stimulate the early events of macrophage activation.
T4 270-491 Sentence denotes The immunological activities of all of these AraLAMs drastically decrease with the loss of the mild alkali groups, which were believed to be restricted to the fatty acid residues from the phosphatidyl-myo-inositol anchor.
T4 270-491 Sentence denotes The immunological activities of all of these AraLAMs drastically decrease with the loss of the mild alkali groups, which were believed to be restricted to the fatty acid residues from the phosphatidyl-myo-inositol anchor.
T5 492-723 Sentence denotes This report reveals the presence and the structure of mild alkali-labile phosphoinositide units linked via the phosphate to the C-5 of the beta-D-Araf in the AraLAMs of Mycobacterium smegmatis, a fast growing mycobacterial species.
T5 492-723 Sentence denotes This report reveals the presence and the structure of mild alkali-labile phosphoinositide units linked via the phosphate to the C-5 of the beta-D-Araf in the AraLAMs of Mycobacterium smegmatis, a fast growing mycobacterial species.
T6 724-1049 Sentence denotes Their structure was unambiguously established with a strategy based on both one-dimensional 31P and two-dimensional 1H-31P heteronuclear multiple quantum correlation spectroscopy (HMQC) and HMQC-homonuclear Hartmann-Hahn spectroscopy NMR experiments applied to native AraLAMs and to AraLAMs treated in mild alkali conditions.
T6 724-1049 Sentence denotes Their structure was unambiguously established with a strategy based on both one-dimensional 31P and two-dimensional 1H-31P heteronuclear multiple quantum correlation spectroscopy (HMQC) and HMQC-homonuclear Hartmann-Hahn spectroscopy NMR experiments applied to native AraLAMs and to AraLAMs treated in mild alkali conditions.
T7 1050-1464 Sentence denotes Next to these alkali-labile phosphoinositides estimated at three per molecule, two other mild alkali-stable phosphoinositide units were identified: the expected (myo-inositol-1)-phosphate-(3-glycerol) unit typifying the well known glycosylphosphatidylinositol anchor of the mannan core and, more surprisingly, one (myo-inositol-1)-phosphate-(5-beta-D-Araf) unit having the same structure as the alkali-labile ones.
T7 1050-1464 Sentence denotes Next to these alkali-labile phosphoinositides estimated at three per molecule, two other mild alkali-stable phosphoinositide units were identified: the expected (myo-inositol-1)-phosphate-(3-glycerol) unit typifying the well known glycosylphosphatidylinositol anchor of the mannan core and, more surprisingly, one (myo-inositol-1)-phosphate-(5-beta-D-Araf) unit having the same structure as the alkali-labile ones.
T8 1465-1553 Sentence denotes Moreover, these four phosphoinositide units were found capping the arabinan side chains.
T8 1465-1553 Sentence denotes Moreover, these four phosphoinositide units were found capping the arabinan side chains.
T9 1554-1686 Sentence denotes Thus, their different behavior toward mild alkaline hydrolysis was explained according to their accessibility to the alkali reagent.
T9 1554-1686 Sentence denotes Thus, their different behavior toward mild alkaline hydrolysis was explained according to their accessibility to the alkali reagent.
T10 1687-1867 Sentence denotes This novel class of LAMs, namely phosphoinositols-glyceroarabinomannans (PI-GAMs), are characterized by their phosphoinositide units but also by the absence of fatty acid residues.
T10 1687-1867 Sentence denotes This novel class of LAMs, namely phosphoinositols-glyceroarabinomannans (PI-GAMs), are characterized by their phosphoinositide units but also by the absence of fatty acid residues.
T11 1868-2037 Sentence denotes These PI-GAMs were found to elicit the secretion of tumor necrosis factor-alpha, suggesting that phosphoinositides are the major PI-GAM epitope involved in this process.
T11 1868-2037 Sentence denotes These PI-GAMs were found to elicit the secretion of tumor necrosis factor-alpha, suggesting that phosphoinositides are the major PI-GAM epitope involved in this process.