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PubMed:8872113 JSONTXT 38 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-128 Sentence denotes Constitutively hyposialylated human T-lymphocyte clones in the Tn-syndrome: binding characteristics of plant and animal lectins.
T1 0-128 Sentence denotes Constitutively hyposialylated human T-lymphocyte clones in the Tn-syndrome: binding characteristics of plant and animal lectins.
TextSentencer_T2 129-330 Sentence denotes Previously, beta 1,3-galactosyltransferase-deficient (Tn+) and normal (TF+) T-lymphocyte clones have been established from a patient suffering from Tn-syndrome [Thurnher et al. (1992) Eur J Immunol 22:
T2 129-330 Sentence denotes Previously, beta 1,3-galactosyltransferase-deficient (Tn+) and normal (TF+) T-lymphocyte clones have been established from a patient suffering from Tn-syndrome [Thurnher et al. (1992) Eur J Immunol 22:
TextSentencer_T3 331-340 Sentence denotes 1835-42].
T3 331-340 Sentence denotes 1835-42].
TextSentencer_T4 341-660 Sentence denotes Tn+ T lymphocytes express only Tn antigen GalNAc alpha 1-O-R) while other O-glycan structures such as sialosyl-Tn (Neu5Ac alpha 2,6GalNAc alpha 1-O-R) or TF (Gal beta 1-3GalNAc alpha 1-O-R) antigens are absent from these cells as shown by flow cytometry using specific mABs for TF and sialosyl-Tn antigen, respectively.
T4 341-660 Sentence denotes Tn+ T lymphocytes express only Tn antigen GalNAc alpha 1-O-R) while other O-glycan structures such as sialosyl-Tn (Neu5Ac alpha 2,6GalNAc alpha 1-O-R) or TF (Gal beta 1-3GalNAc alpha 1-O-R) antigens are absent from these cells as shown by flow cytometry using specific mABs for TF and sialosyl-Tn antigen, respectively.
TextSentencer_T5 661-729 Sentence denotes Normal T lymphocytes express the TF antigen and derivatives thereof.
T5 661-729 Sentence denotes Normal T lymphocytes express the TF antigen and derivatives thereof.
TextSentencer_T6 730-856 Sentence denotes The surface glycans of Tn+ and TF+ cells were then analysed by flow cytometry using the following sialic acid-binding lectins:
T6 730-856 Sentence denotes The surface glycans of Tn+ and TF+ cells were then analysed by flow cytometry using the following sialic acid-binding lectins:
TextSentencer_T7 857-977 Sentence denotes Amaranthus caudatus (ACA), Maackia amurensis (MAA), Limax flavus (LFA), Sambucus nigra (SNA) and Triticum vulgare (WGA).
T7 857-977 Sentence denotes Amaranthus caudatus (ACA), Maackia amurensis (MAA), Limax flavus (LFA), Sambucus nigra (SNA) and Triticum vulgare (WGA).
TextSentencer_T8 978-1052 Sentence denotes Equal and weak binding of MAA and SNA to both TF+ and Tn+ cells was found.
T8 978-1052 Sentence denotes Equal and weak binding of MAA and SNA to both TF+ and Tn+ cells was found.
TextSentencer_T9 1053-1121 Sentence denotes WGA, LFA and ACA bound more strongly to TF+ cells than to Tn+ cells.
T9 1053-1121 Sentence denotes WGA, LFA and ACA bound more strongly to TF+ cells than to Tn+ cells.
TextSentencer_T10 1122-1189 Sentence denotes Binding of ACA to TF+ cells was enhanced after sialidase treatment.
T10 1122-1189 Sentence denotes Binding of ACA to TF+ cells was enhanced after sialidase treatment.
TextSentencer_T11 1190-1455 Sentence denotes To investigate the possible biological consequences of hyposialylation, binding of three sialic acid-dependent adhesion molecules to Tn+ and TF+ cells was estimated using radiolabelled Fc-chimeras of sialoadhesin (Sn), myelin-associated glycoprotein (MAG) and CD22.
T11 1190-1455 Sentence denotes To investigate the possible biological consequences of hyposialylation, binding of three sialic acid-dependent adhesion molecules to Tn+ and TF+ cells was estimated using radiolabelled Fc-chimeras of sialoadhesin (Sn), myelin-associated glycoprotein (MAG) and CD22.
TextSentencer_T12 1456-1531 Sentence denotes Equal and strong binding of human CD22 to both TF+ and Tn+ cells was found.
T12 1456-1531 Sentence denotes Equal and strong binding of human CD22 to both TF+ and Tn+ cells was found.
TextSentencer_T13 1532-1655 Sentence denotes Whereas binding of Sn and MAG to TF+ cells was strong (100%), binding to Tn+ cells amounted only to 33% (Sn) and 19% (MAG).
T13 1532-1655 Sentence denotes Whereas binding of Sn and MAG to TF+ cells was strong (100%), binding to Tn+ cells amounted only to 33% (Sn) and 19% (MAG).
TextSentencer_T14 1656-1851 Sentence denotes These results indicate that the in vivo interactions of T lymphocytes in the Tn syndrome with CD22 are not likely to be affected, whereas adhesion mediated by Sn or MAG could be strongly reduced.
T14 1656-1851 Sentence denotes These results indicate that the in vivo interactions of T lymphocytes in the Tn syndrome with CD22 are not likely to be affected, whereas adhesion mediated by Sn or MAG could be strongly reduced.