| Id |
Subject |
Object |
Predicate |
Lexical cue |
| TextSentencer_T1 |
0-152 |
Sentence |
denotes |
Identification of O-sulphate substituents on D-glucuronic acid units in heparin-related glycosaminoglycans using novel synthetic disaccharide standards. |
| T1 |
0-152 |
Sentence |
denotes |
Identification of O-sulphate substituents on D-glucuronic acid units in heparin-related glycosaminoglycans using novel synthetic disaccharide standards. |
| T1 |
0-152 |
Sentence |
denotes |
Identification of O-sulphate substituents on D-glucuronic acid units in heparin-related glycosaminoglycans using novel synthetic disaccharide standards. |
| TextSentencer_T2 |
153-555 |
Sentence |
denotes |
The two disaccharides, methyl 4-O-(2-O-sulpho-beta-D-glucopyranosyl-uronic acid)-2-deoxy-2-amino-alpha-D-glucopyranoside and methyl 4-O-(3-O-sulpho-beta-D-glucopyranosyluronic acid)-2-deoxy-2-amino-alpha-D-glucopyranoside, were prepared by de novo synthesis, and converted to the corresponding 2,5-anhydro-D-[1-3H]mannitol derivatives by deamination with nitrous acid followed by reduction with NaB3H4. |
| T2 |
153-555 |
Sentence |
denotes |
The two disaccharides, methyl 4-O-(2-O-sulpho-beta-D-glucopyranosyl-uronic acid)-2-deoxy-2-amino-alpha-D-glucopyranoside and methyl 4-O-(3-O-sulpho-beta-D-glucopyranosyluronic acid)-2-deoxy-2-amino-alpha-D-glucopyranoside, were prepared by de novo synthesis, and converted to the corresponding 2,5-anhydro-D-[1-3H]mannitol derivatives by deamination with nitrous acid followed by reduction with NaB3H4. |
| T2 |
153-555 |
Sentence |
denotes |
The two disaccharides, methyl 4-O-(2-O-sulpho-beta-D-glucopyranosyl-uronic acid)-2-deoxy-2-amino-alpha-D-glucopyranoside and methyl 4-O-(3-O-sulpho-beta-D-glucopyranosyluronic acid)-2-deoxy-2-amino-alpha-D-glucopyranoside, were prepared by de novo synthesis, and converted to the corresponding 2,5-anhydro-D-[1-3H]mannitol derivatives by deamination with nitrous acid followed by reduction with NaB3H4. |
| TextSentencer_T3 |
556-797 |
Sentence |
denotes |
The resultant labelled products were used as standards in the identification, by anion-exchange high-performance liquid chromatography (HPLC), of disaccharides generated by HNO2/NaB3H4 treatment of heparan sulphate isolated from human brain. |
| T3 |
556-797 |
Sentence |
denotes |
The resultant labelled products were used as standards in the identification, by anion-exchange high-performance liquid chromatography (HPLC), of disaccharides generated by HNO2/NaB3H4 treatment of heparan sulphate isolated from human brain. |
| T3 |
556-797 |
Sentence |
denotes |
The resultant labelled products were used as standards in the identification, by anion-exchange high-performance liquid chromatography (HPLC), of disaccharides generated by HNO2/NaB3H4 treatment of heparan sulphate isolated from human brain. |
| TextSentencer_T4 |
798-927 |
Sentence |
denotes |
The two standards, containing 2-O- and 3-O-sulphated glucuronic acid, respectively, were clearly separated by the HPLC procedure. |
| T4 |
798-927 |
Sentence |
denotes |
The two standards, containing 2-O- and 3-O-sulphated glucuronic acid, respectively, were clearly separated by the HPLC procedure. |
| T4 |
798-927 |
Sentence |
denotes |
The two standards, containing 2-O- and 3-O-sulphated glucuronic acid, respectively, were clearly separated by the HPLC procedure. |
| TextSentencer_T5 |
928-1139 |
Sentence |
denotes |
Comparison with the deamination products derived from heparan sulphate showed that the mono-O-sulphated disaccharide species containing a sulphated glucuronic acid unit co-eluted with the 2-O-sulphated standard. |
| T5 |
928-1139 |
Sentence |
denotes |
Comparison with the deamination products derived from heparan sulphate showed that the mono-O-sulphated disaccharide species containing a sulphated glucuronic acid unit co-eluted with the 2-O-sulphated standard. |
| T5 |
928-1139 |
Sentence |
denotes |
Comparison with the deamination products derived from heparan sulphate showed that the mono-O-sulphated disaccharide species containing a sulphated glucuronic acid unit co-eluted with the 2-O-sulphated standard. |
| TextSentencer_T6 |
1140-1269 |
Sentence |
denotes |
The corresponding component isolated from other heparan sulphate preparations, or from heparin, also eluted at the same position. |
| T6 |
1140-1269 |
Sentence |
denotes |
The corresponding component isolated from other heparan sulphate preparations, or from heparin, also eluted at the same position. |
| T6 |
1140-1269 |
Sentence |
denotes |
The corresponding component isolated from other heparan sulphate preparations, or from heparin, also eluted at the same position. |
| TextSentencer_T7 |
1270-1390 |
Sentence |
denotes |
No disaccharide derived from heparin or heparan sulphate appeared at the elution position of the 3-O-sulphated standard. |
| T7 |
1270-1390 |
Sentence |
denotes |
No disaccharide derived from heparin or heparan sulphate appeared at the elution position of the 3-O-sulphated standard. |
| T7 |
1270-1390 |
Sentence |
denotes |
No disaccharide derived from heparin or heparan sulphate appeared at the elution position of the 3-O-sulphated standard. |
| TextSentencer_T8 |
1391-1554 |
Sentence |
denotes |
It is concluded that D-glucuronic acid units in heparin-related glycosaminoglycans may be sulphated at C2, whereas no evidence has been found for sulphation at C3. |
| T8 |
1391-1554 |
Sentence |
denotes |
It is concluded that D-glucuronic acid units in heparin-related glycosaminoglycans may be sulphated at C2, whereas no evidence has been found for sulphation at C3. |
| T8 |
1391-1554 |
Sentence |
denotes |
It is concluded that D-glucuronic acid units in heparin-related glycosaminoglycans may be sulphated at C2, whereas no evidence has been found for sulphation at C3. |
| TextSentencer_T9 |
1555-1808 |
Sentence |
denotes |
By contrast, analysis of mono-O-sulphated disaccharides derived from a chemically sulphated, bacterial capsular polysaccharide (generated by Escherichia coli K5) clearly demonstrated the occurrence of O-sulphate groups at C-3 of D-glucuronic acid units. |
| T9 |
1555-1808 |
Sentence |
denotes |
By contrast, analysis of mono-O-sulphated disaccharides derived from a chemically sulphated, bacterial capsular polysaccharide (generated by Escherichia coli K5) clearly demonstrated the occurrence of O-sulphate groups at C-3 of D-glucuronic acid units. |
| T9 |
1555-1808 |
Sentence |
denotes |
By contrast, analysis of mono-O-sulphated disaccharides derived from a chemically sulphated, bacterial capsular polysaccharide (generated by Escherichia coli K5) clearly demonstrated the occurrence of O-sulphate groups at C-3 of D-glucuronic acid units. |