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PubMed:8663060 JSONTXT 32 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
T1 0-131 Sentence denotes Tissue-specific activity of the gammac chain gene promoter depends upon an Ets binding site and is regulated by GA-binding protein.
T1 0-131 Sentence denotes Tissue-specific activity of the gammac chain gene promoter depends upon an Ets binding site and is regulated by GA-binding protein.
T2 132-308 Sentence denotes The gammac chain is a subunit of multiple cytokine receptors (interleukin (IL)-2, IL-4, IL-7, IL-9, and IL-15), the expression of which is restricted to hematopoietic lineages.
T2 132-308 Sentence denotes The gammac chain is a subunit of multiple cytokine receptors (interleukin (IL)-2, IL-4, IL-7, IL-9, and IL-15), the expression of which is restricted to hematopoietic lineages.
T3 309-434 Sentence denotes A defect in gammac leads to the X-linked severe combined immunodeficiency characterized by a block in T cell differentiation.
T3 309-434 Sentence denotes A defect in gammac leads to the X-linked severe combined immunodeficiency characterized by a block in T cell differentiation.
T4 435-775 Sentence denotes In order to better characterize the human gammac promoter and define the minimal tissue-specific promoter region, progressive 5'-deletion constructs of a segment extending 1053 base pairs upstream of the major transcription start site were generated and tested for promoter activity in various hematopoietic and nonhematopoietic cell types.
T4 435-775 Sentence denotes In order to better characterize the human gammac promoter and define the minimal tissue-specific promoter region, progressive 5'-deletion constructs of a segment extending 1053 base pairs upstream of the major transcription start site were generated and tested for promoter activity in various hematopoietic and nonhematopoietic cell types.
T5 776-933 Sentence denotes The -1053/+34 construct allowed promoter activity only in cells of hematopoietic origin, and tissue specificity was conserved in all other constructs tested.
T5 776-933 Sentence denotes The -1053/+34 construct allowed promoter activity only in cells of hematopoietic origin, and tissue specificity was conserved in all other constructs tested.
T6 934-1009 Sentence denotes The region downstream of -90 appeared critical for basal promoter activity.
T6 934-1009 Sentence denotes The region downstream of -90 appeared critical for basal promoter activity.
T7 1010-1203 Sentence denotes It contains two potential Ets binding sites conserved in the murine gammac promoter gene, one of which was found essential for functional promoter activity as determined by mutational analysis.
T7 1010-1203 Sentence denotes It contains two potential Ets binding sites conserved in the murine gammac promoter gene, one of which was found essential for functional promoter activity as determined by mutational analysis.
T8 1204-1383 Sentence denotes The functional Ets binding site was found to bind Ets family proteins, principally GA-binding protein and Elf-1 and could be transactivated by GABPalpha and -beta synergistically.
T8 1204-1383 Sentence denotes The functional Ets binding site was found to bind Ets family proteins, principally GA-binding protein and Elf-1 and could be transactivated by GABPalpha and -beta synergistically.
T9 1384-1539 Sentence denotes These results indicate that, as already reported for the IL2Rbeta promoter, GA-binding protein is an essential component of gammac basal promoter activity.
T9 1384-1539 Sentence denotes These results indicate that, as already reported for the IL2Rbeta promoter, GA-binding protein is an essential component of gammac basal promoter activity.
T10 1540-1725 Sentence denotes Although GABP expression is not restricted to the hematopoietic lineage, its interaction with other specific factors may contribute to the tissue-specific expression of the gammac gene.
T10 1540-1725 Sentence denotes Although GABP expression is not restricted to the hematopoietic lineage, its interaction with other specific factors may contribute to the tissue-specific expression of the gammac gene.