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PubMed:8663022 JSONTXT 30 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
T1 0-92 Sentence denotes Octamer binding factors and their coactivator can activate the murine PU.1 (spi-1) promoter.
T1 0-92 Sentence denotes Octamer binding factors and their coactivator can activate the murine PU.1 (spi-1) promoter.
T2 93-306 Sentence denotes PU.1 (spi-1), a member of the Ets transcription factor family, is predominantly expressed in myeloid and B cells, activates many B cell and myeloid genes, and is critical for development of both of these lineages.
T2 93-306 Sentence denotes PU.1 (spi-1), a member of the Ets transcription factor family, is predominantly expressed in myeloid and B cells, activates many B cell and myeloid genes, and is critical for development of both of these lineages.
T3 307-337 Sentence denotes Our previous studies (Chen, H.
T3 307-337 Sentence denotes Our previous studies (Chen, H.
T4 338-385 Sentence denotes M., Ray-Gallet, D., Zhang, P., Hetherington, C.
T4 338-385 Sentence denotes M., Ray-Gallet, D., Zhang, P., Hetherington, C.
T5 386-402 Sentence denotes J., Gonzalez, D.
T5 386-402 Sentence denotes J., Gonzalez, D.
T6 403-455 Sentence denotes A., Zhang, D.-E., Moreau-Gachelin, F., and Tenen, D.
T6 403-455 Sentence denotes A., Zhang, D.-E., Moreau-Gachelin, F., and Tenen, D.
T7 456-667 Sentence denotes G. (1995) Oncogene 11, 1549-1560) demonstrate that the PU.1 promoter directs cell type-specific reporter gene expression in myeloid cell lines, and that PU.1 activates its own promoter in an autoregulatory loop.
T7 456-667 Sentence denotes G. (1995) Oncogene 11, 1549-1560) demonstrate that the PU.1 promoter directs cell type-specific reporter gene expression in myeloid cell lines, and that PU.1 activates its own promoter in an autoregulatory loop.
T8 668-778 Sentence denotes Here we show that the murine PU.1 promoter is also specifically and highly functional in B cell lines as well.
T8 668-778 Sentence denotes Here we show that the murine PU.1 promoter is also specifically and highly functional in B cell lines as well.
T9 779-913 Sentence denotes Oct-1 and Oct-2 can bind specifically to a site at base pair -55 in vitro, and this site is specifically protected in B cells in vivo.
T9 779-913 Sentence denotes Oct-1 and Oct-2 can bind specifically to a site at base pair -55 in vitro, and this site is specifically protected in B cells in vivo.
T10 914-1082 Sentence denotes We also demonstrate that two other sites contribute to promoter activity in B cells; an Sp1 binding site adjacent to the octamer site, and the PU.1 autoregulatory site.
T10 914-1082 Sentence denotes We also demonstrate that two other sites contribute to promoter activity in B cells; an Sp1 binding site adjacent to the octamer site, and the PU.1 autoregulatory site.
T11 1083-1288 Sentence denotes Finally, we show that the B cell coactivator OBF-1/Bob1/OCA-B is only expressed in B cells and not in myeloid cells, and that OBF-1/Bob1/OCA-B can transactivate the PU.1 promoter in HeLa and myeloid cells.
T11 1083-1288 Sentence denotes Finally, we show that the B cell coactivator OBF-1/Bob1/OCA-B is only expressed in B cells and not in myeloid cells, and that OBF-1/Bob1/OCA-B can transactivate the PU.1 promoter in HeLa and myeloid cells.
T12 1289-1415 Sentence denotes This B cell restricted coactivator may be responsible for the B cell specific expression of PU.1 mediated by the octamer site.
T12 1289-1415 Sentence denotes This B cell restricted coactivator may be responsible for the B cell specific expression of PU.1 mediated by the octamer site.