> top > projects > sentences > docs > PubMed:8631864 > annotations
sentences Home  

PubMed:8631864 JSONTXT 37 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
T1 0-81 Sentence denotes Characterization of an alternatively spliced GM2 activator protein, GM2A protein.
T1 0-81 Sentence denotes Characterization of an alternatively spliced GM2 activator protein, GM2A protein.
T2 82-213 Sentence denotes An activator protein which stimulates the enzymatic hydrolysis of N-acetylneuraminic acid, but not N-acetylgalactosamine, from GM2.
T2 82-213 Sentence denotes An activator protein which stimulates the enzymatic hydrolysis of N-acetylneuraminic acid, but not N-acetylgalactosamine, from GM2.
T3 214-334 Sentence denotes GM2 activator protein is a protein cofactor which stimulates the enzymatic hydrolysis of both GalNAc and NeuAc from GM2.
T3 214-334 Sentence denotes GM2 activator protein is a protein cofactor which stimulates the enzymatic hydrolysis of both GalNAc and NeuAc from GM2.
T4 335-512 Sentence denotes We have previously isolated two cDNA clones, GM2 activator cDNA and GM2A cDNA, for human GM2 activator protein (Nagarajan, S., Chen, H.-C., Li, S.-C., Li, Y.-T., and Lockyer, J.
T4 335-512 Sentence denotes We have previously isolated two cDNA clones, GM2 activator cDNA and GM2A cDNA, for human GM2 activator protein (Nagarajan, S., Chen, H.-C., Li, S.-C., Li, Y.-T., and Lockyer, J.
T5 513-531 Sentence denotes M. (1992) Biochem.
T5 513-531 Sentence denotes M. (1992) Biochem.
T6 532-534 Sentence denotes J.
T6 532-534 Sentence denotes J.
T7 535-549 Sentence denotes 282, 807-813).
T7 535-549 Sentence denotes 282, 807-813).
T8 550-804 Sentence denotes GM2A mRNA is an RNA alternative splicing product that contains exons 1, 2, 3, and intron 3 of the genomic DNA sequence of GM2 activator protein (Klima, H., Tanaka, A., Schnabel, D., Nakano, T., Schröder, M., Suzuki, K., and Sandhoff, K. (1991) FEBS Lett.
T8 550-804 Sentence denotes GM2A mRNA is an RNA alternative splicing product that contains exons 1, 2, 3, and intron 3 of the genomic DNA sequence of GM2 activator protein (Klima, H., Tanaka, A., Schnabel, D., Nakano, T., Schröder, M., Suzuki, K., and Sandhoff, K. (1991) FEBS Lett.
T9 805-819 Sentence denotes 289, 260-264).
T9 805-819 Sentence denotes 289, 260-264).
T10 820-1000 Sentence denotes GM2A cDNA encodes a protein (GM2A protein) containing 1-109 of the 160 amino acids of human GM2 activator protein, plus a tripeptide (VST) encoded by intron 3 at the COOH terminus.
T10 820-1000 Sentence denotes GM2A cDNA encodes a protein (GM2A protein) containing 1-109 of the 160 amino acids of human GM2 activator protein, plus a tripeptide (VST) encoded by intron 3 at the COOH terminus.
T11 1001-1091 Sentence denotes Thus, GM2A protein can be regarded as a form (truncated version) of GM2 activator protein.
T11 1001-1091 Sentence denotes Thus, GM2A protein can be regarded as a form (truncated version) of GM2 activator protein.
T12 1092-1166 Sentence denotes We have expressed GM2A cDNA in Escherichia coli using pT7-7 as the vector.
T12 1092-1166 Sentence denotes We have expressed GM2A cDNA in Escherichia coli using pT7-7 as the vector.
T13 1167-1405 Sentence denotes The recombinant GM2A protein was purified to an electrophoretically homogeneous form and was found to stimulate the hydrolysis of NeuAc from GM2 by clostridial sialidase, but not the hydrolysis of GalNAc from GM2 by beta-hexosaminidase A.
T13 1167-1405 Sentence denotes The recombinant GM2A protein was purified to an electrophoretically homogeneous form and was found to stimulate the hydrolysis of NeuAc from GM2 by clostridial sialidase, but not the hydrolysis of GalNAc from GM2 by beta-hexosaminidase A.
T14 1406-1620 Sentence denotes Like GM2 activator protein, GM2A protein also specifically recognized the terminal GM2 epitope in GalNAc-GD1a and stimulated the hydrolysis of only the external NeuAc from this ganglioside by clostridial sialidase.
T14 1406-1620 Sentence denotes Like GM2 activator protein, GM2A protein also specifically recognized the terminal GM2 epitope in GalNAc-GD1a and stimulated the hydrolysis of only the external NeuAc from this ganglioside by clostridial sialidase.
T15 1621-1834 Sentence denotes These results enabled us to discern the enzymatic hydrolyses of GalNAc and NeuAc from the GM2 epitope and established that the NeuAc recognition domain of GM2 activator protein is located within amino acids 1-109.
T15 1621-1834 Sentence denotes These results enabled us to discern the enzymatic hydrolyses of GalNAc and NeuAc from the GM2 epitope and established that the NeuAc recognition domain of GM2 activator protein is located within amino acids 1-109.
T16 1835-2053 Sentence denotes The presence of GM2A mRNA in human tissues and the selective stimulation of NeuAc hydrolysis by GM2A protein indicate that this activator protein may be involved in the catabolism of GM2 through the asialo-GM2 pathway.
T16 1835-2053 Sentence denotes The presence of GM2A mRNA in human tissues and the selective stimulation of NeuAc hydrolysis by GM2A protein indicate that this activator protein may be involved in the catabolism of GM2 through the asialo-GM2 pathway.