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PubMed:8621390 JSONTXT 31 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
T1 0-94 Sentence denotes Transcriptional regulation of the interleukin-2 gene in normal human peripheral blood T cells.
T1 0-94 Sentence denotes Transcriptional regulation of the interleukin-2 gene in normal human peripheral blood T cells.
T2 95-173 Sentence denotes Convergence of costimulatory signals and differences from transformed T cells.
T2 95-173 Sentence denotes Convergence of costimulatory signals and differences from transformed T cells.
T3 174-291 Sentence denotes To study transcriptional regulation in normal human T cells, we have optimized conditions for transient transfection.
T3 174-291 Sentence denotes To study transcriptional regulation in normal human T cells, we have optimized conditions for transient transfection.
T4 292-440 Sentence denotes Interleukin-2 (IL-2) promoter-reporter gene behavior closely parallels the endogenous gene in response to T cell receptor and costimulatory signals.
T4 292-440 Sentence denotes Interleukin-2 (IL-2) promoter-reporter gene behavior closely parallels the endogenous gene in response to T cell receptor and costimulatory signals.
T5 441-598 Sentence denotes As assessed with mutagenized promoters, the most important IL-2 cis-regulatory elements in normal T cells are the proximal AP-1 site and the NF- kappaB site.
T5 441-598 Sentence denotes As assessed with mutagenized promoters, the most important IL-2 cis-regulatory elements in normal T cells are the proximal AP-1 site and the NF- kappaB site.
T6 599-839 Sentence denotes Both primary activation, with phytohemagglutinin or antibodies to CD3, and costimulation, provided by pairs of CD2 antibodies or B7-positive (B cells) or B7-negative (endothelial) accessory cells, are mediated through the same cis-elements.
T6 599-839 Sentence denotes Both primary activation, with phytohemagglutinin or antibodies to CD3, and costimulation, provided by pairs of CD2 antibodies or B7-positive (B cells) or B7-negative (endothelial) accessory cells, are mediated through the same cis-elements.
T7 840-965 Sentence denotes Interestingly, the nuclear factor of activated T cell sites are much less important in normal T cells than in Jurkat T cells.
T7 840-965 Sentence denotes Interestingly, the nuclear factor of activated T cell sites are much less important in normal T cells than in Jurkat T cells.
T8 966-1168 Sentence denotes We conclude that IL-2 transcriptional regulation differs in tumor cell lines compared with normal T cells and that different costimulatory signals converge on the same cis-elements in the IL-2 promoter.
T8 966-1168 Sentence denotes We conclude that IL-2 transcriptional regulation differs in tumor cell lines compared with normal T cells and that different costimulatory signals converge on the same cis-elements in the IL-2 promoter.