| Id |
Subject |
Object |
Predicate |
Lexical cue |
| TextSentencer_T1 |
0-81 |
Sentence |
denotes |
Biological and immunochemical characterization of recombinant human thyrotrophin. |
| T1 |
0-81 |
Sentence |
denotes |
Biological and immunochemical characterization of recombinant human thyrotrophin. |
| T1 |
0-81 |
Sentence |
denotes |
Biological and immunochemical characterization of recombinant human thyrotrophin. |
| TextSentencer_T2 |
82-238 |
Sentence |
denotes |
Recombinant human thyroid-stimulating hormone (recTSH) has recently been engineered to detect metastatic lesions in patients operated on for thyroid cancer. |
| T2 |
82-238 |
Sentence |
denotes |
Recombinant human thyroid-stimulating hormone (recTSH) has recently been engineered to detect metastatic lesions in patients operated on for thyroid cancer. |
| T2 |
82-238 |
Sentence |
denotes |
Recombinant human thyroid-stimulating hormone (recTSH) has recently been engineered to detect metastatic lesions in patients operated on for thyroid cancer. |
| TextSentencer_T3 |
239-443 |
Sentence |
denotes |
In this report, we have compared the microheterogeneity, carbohydrate (CHO) content, mitogenic potency and immunoreactivity of the biotechnology product to those of human TSH of pituitary origin (pitTSH). |
| T3 |
239-443 |
Sentence |
denotes |
In this report, we have compared the microheterogeneity, carbohydrate (CHO) content, mitogenic potency and immunoreactivity of the biotechnology product to those of human TSH of pituitary origin (pitTSH). |
| T3 |
239-443 |
Sentence |
denotes |
In this report, we have compared the microheterogeneity, carbohydrate (CHO) content, mitogenic potency and immunoreactivity of the biotechnology product to those of human TSH of pituitary origin (pitTSH). |
| TextSentencer_T4 |
444-694 |
Sentence |
denotes |
Compositional analysis revealed that recombinant (rec) TSH produced in Chinese hamster ovary cells was overglycosylated compared with the native hormone (21 and 14%, respectively) with a higher amount of sialic acid and lack of N-acetylgalactosamine. |
| T4 |
444-694 |
Sentence |
denotes |
Compositional analysis revealed that recombinant (rec) TSH produced in Chinese hamster ovary cells was overglycosylated compared with the native hormone (21 and 14%, respectively) with a higher amount of sialic acid and lack of N-acetylgalactosamine. |
| T4 |
444-694 |
Sentence |
denotes |
Compositional analysis revealed that recombinant (rec) TSH produced in Chinese hamster ovary cells was overglycosylated compared with the native hormone (21 and 14%, respectively) with a higher amount of sialic acid and lack of N-acetylgalactosamine. |
| TextSentencer_T5 |
695-999 |
Sentence |
denotes |
Electrofocusing followed by immunoblotting resolved recTSH into six glycoforms with pIs ranging from 6.0 to 8.6, which were converted to a major species of pI 8.9 by sialidase treatment. pitTSH contained five main isoforms of pI 6.5-8.2 distinct from those of recTSH and partially resistant to sialidase. |
| T5 |
695-999 |
Sentence |
denotes |
Electrofocusing followed by immunoblotting resolved recTSH into six glycoforms with pIs ranging from 6.0 to 8.6, which were converted to a major species of pI 8.9 by sialidase treatment. pitTSH contained five main isoforms of pI 6.5-8.2 distinct from those of recTSH and partially resistant to sialidase. |
| T5 |
695-999 |
Sentence |
denotes |
Electrofocusing followed by immunoblotting resolved recTSH into six glycoforms with pIs ranging from 6.0 to 8.6, which were converted to a major species of pI 8.9 by sialidase treatment. pitTSH contained five main isoforms of pI 6.5-8.2 distinct from those of recTSH and partially resistant to sialidase. |
| TextSentencer_T6 |
1000-1220 |
Sentence |
denotes |
Binding activity of both human TSHs to porcine thyroid membrane receptors was found to be similar, but recTSH appeared to be 20% active compared to pitTSH in eliciting cAMP production and cell growth in rat FRTL-5 cells. |
| T6 |
1000-1220 |
Sentence |
denotes |
Binding activity of both human TSHs to porcine thyroid membrane receptors was found to be similar, but recTSH appeared to be 20% active compared to pitTSH in eliciting cAMP production and cell growth in rat FRTL-5 cells. |
| T6 |
1000-1220 |
Sentence |
denotes |
Binding activity of both human TSHs to porcine thyroid membrane receptors was found to be similar, but recTSH appeared to be 20% active compared to pitTSH in eliciting cAMP production and cell growth in rat FRTL-5 cells. |
| TextSentencer_T7 |
1221-1406 |
Sentence |
denotes |
Immunoreactivity of the recombinant hormone was investigated using polyclonal and monoclonal antibodies raised against the native hormone or synthetic peptide sequences of its subunits. |
| T7 |
1221-1406 |
Sentence |
denotes |
Immunoreactivity of the recombinant hormone was investigated using polyclonal and monoclonal antibodies raised against the native hormone or synthetic peptide sequences of its subunits. |
| T7 |
1221-1406 |
Sentence |
denotes |
Immunoreactivity of the recombinant hormone was investigated using polyclonal and monoclonal antibodies raised against the native hormone or synthetic peptide sequences of its subunits. |
| TextSentencer_T8 |
1407-1562 |
Sentence |
denotes |
While rec- and pitTSH were recognized to a similar extent by anti-protein antibodies, they exhibited a different binding pattern to antipeptide antibodies. |
| T8 |
1407-1562 |
Sentence |
denotes |
While rec- and pitTSH were recognized to a similar extent by anti-protein antibodies, they exhibited a different binding pattern to antipeptide antibodies. |
| T8 |
1407-1562 |
Sentence |
denotes |
While rec- and pitTSH were recognized to a similar extent by anti-protein antibodies, they exhibited a different binding pattern to antipeptide antibodies. |
| TextSentencer_T9 |
1563-1819 |
Sentence |
denotes |
Serial dilution of anti-alpha 1-25, anti-alpha 26-51, anti-beta 96-112 antisera bound recTSH to a greater extent than pitTSH, while anti-beta 31-51 and anti-beta 53-76 displayed similar recognition toward both preparations.(ABSTRACT TRUNCATED AT 250 WORDS) |
| T9 |
1563-1819 |
Sentence |
denotes |
Serial dilution of anti-alpha 1-25, anti-alpha 26-51, anti-beta 96-112 antisera bound recTSH to a greater extent than pitTSH, while anti-beta 31-51 and anti-beta 53-76 displayed similar recognition toward both preparations.(ABSTRACT TRUNCATED AT 250 WORDS) |
| T9 |
1563-1819 |
Sentence |
denotes |
Serial dilution of anti-alpha 1-25, anti-alpha 26-51, anti-beta 96-112 antisera bound recTSH to a greater extent than pitTSH, while anti-beta 31-51 and anti-beta 53-76 displayed similar recognition toward both preparations.(ABSTRACT TRUNCATED AT 250 WORDS) |