| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T1 |
0-52 |
Sentence |
denotes |
Oxidoreductive regulation of nuclear factor kappa B. |
| T1 |
0-52 |
Sentence |
denotes |
Oxidoreductive regulation of nuclear factor kappa B. |
| T2 |
53-109 |
Sentence |
denotes |
Involvement of a cellular reducing catalyst thioredoxin. |
| T2 |
53-109 |
Sentence |
denotes |
Involvement of a cellular reducing catalyst thioredoxin. |
| T3 |
110-401 |
Sentence |
denotes |
We have investigated an oxidoreductive regulatory pathway for the DNA binding activity of a pleiotropic cellular transcription factor, nuclear factor kappa B (NF kappa B), has been investigated by using NF kappa B prepared from the nucleus and the cytosol of the primary human T lymphocytes. |
| T3 |
110-401 |
Sentence |
denotes |
We have investigated an oxidoreductive regulatory pathway for the DNA binding activity of a pleiotropic cellular transcription factor, nuclear factor kappa B (NF kappa B), has been investigated by using NF kappa B prepared from the nucleus and the cytosol of the primary human T lymphocytes. |
| T4 |
402-616 |
Sentence |
denotes |
We show that a cellular reducing catalyst thioredoxin (Trx) plays a major role in activation of the DNA binding of NF kappa B in vitro and stimulation of transcription from the NF kappa B-dependent gene expression. |
| T4 |
402-616 |
Sentence |
denotes |
We show that a cellular reducing catalyst thioredoxin (Trx) plays a major role in activation of the DNA binding of NF kappa B in vitro and stimulation of transcription from the NF kappa B-dependent gene expression. |
| T5 |
617-824 |
Sentence |
denotes |
We demonstrate evidence suggesting that redox regulation of NF kappa B by Trx might be exerted at a step after dissociation of the inhibitory molecule I kappa B, a cytosolic-anchoring protein for NF kappa B. |
| T5 |
617-824 |
Sentence |
denotes |
We demonstrate evidence suggesting that redox regulation of NF kappa B by Trx might be exerted at a step after dissociation of the inhibitory molecule I kappa B, a cytosolic-anchoring protein for NF kappa B. |
| T6 |
825-1082 |
Sentence |
denotes |
To examine the effect of Trx in intact cells, we performed transient assay with a chloramphenicol acetyltransferase-expressing plasmid under the control of human immunodeficiency virus (HIV) long terminal repeat and an effector plasmid expressing human Trx. |
| T6 |
825-1082 |
Sentence |
denotes |
To examine the effect of Trx in intact cells, we performed transient assay with a chloramphenicol acetyltransferase-expressing plasmid under the control of human immunodeficiency virus (HIV) long terminal repeat and an effector plasmid expressing human Trx. |
| T7 |
1083-1263 |
Sentence |
denotes |
The promoter activity from HIV long terminal repeat was greatly augmented by co-transfecting the Trx-expressing plasmid, whose effect was dependent on the NF kappa B-binding sites. |
| T7 |
1083-1263 |
Sentence |
denotes |
The promoter activity from HIV long terminal repeat was greatly augmented by co-transfecting the Trx-expressing plasmid, whose effect was dependent on the NF kappa B-binding sites. |
| T8 |
1264-1513 |
Sentence |
denotes |
These findings have suggested that cysteine residue(s) of NF kappa B might be involved in the DNA-recognition by NF kappa B and that the redox control mechanism mediated by Trx might have a regulatory role in the NF kappa B-mediated gene expression. |
| T8 |
1264-1513 |
Sentence |
denotes |
These findings have suggested that cysteine residue(s) of NF kappa B might be involved in the DNA-recognition by NF kappa B and that the redox control mechanism mediated by Trx might have a regulatory role in the NF kappa B-mediated gene expression. |
| T9 |
1514-1657 |
Sentence |
denotes |
These results may also provide a clue to understanding of the molecular process of AIDS pathogenesis and its possible biochemical intervention. |
| T9 |
1514-1657 |
Sentence |
denotes |
These results may also provide a clue to understanding of the molecular process of AIDS pathogenesis and its possible biochemical intervention. |