| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T1 |
0-82 |
Sentence |
denotes |
ras protein activity is essential for T-cell antigen receptor signal transduction. |
| T1 |
0-82 |
Sentence |
denotes |
ras protein activity is essential for T-cell antigen receptor signal transduction. |
| T2 |
83-268 |
Sentence |
denotes |
In a Jurkat cell model of T-cell activation an interleukin-2 promoter/reporter gene construct was activated by antigen receptor agonism in combination with the lymphokine interleukin-1. |
| T2 |
83-268 |
Sentence |
denotes |
In a Jurkat cell model of T-cell activation an interleukin-2 promoter/reporter gene construct was activated by antigen receptor agonism in combination with the lymphokine interleukin-1. |
| T3 |
269-440 |
Sentence |
denotes |
Antigen receptor signals could be mimicked by suboptimal activation of protein kinase C (PKC) with phorbol esters in combination with calcium mobilization by an ionophore. |
| T3 |
269-440 |
Sentence |
denotes |
Antigen receptor signals could be mimicked by suboptimal activation of protein kinase C (PKC) with phorbol esters in combination with calcium mobilization by an ionophore. |
| T4 |
441-588 |
Sentence |
denotes |
In cotransfection experiments, oncogenic rats obviated the need for PKC stimulation but did not replace either the calcium signal or interleukin-1. |
| T4 |
441-588 |
Sentence |
denotes |
In cotransfection experiments, oncogenic rats obviated the need for PKC stimulation but did not replace either the calcium signal or interleukin-1. |
| T5 |
589-719 |
Sentence |
denotes |
Activated ras expression also replaced the requirement for PKC stimulation in activation of the T-cell transcription factor NF-AT. |
| T5 |
589-719 |
Sentence |
denotes |
Activated ras expression also replaced the requirement for PKC stimulation in activation of the T-cell transcription factor NF-AT. |
| T6 |
720-872 |
Sentence |
denotes |
A dominant inhibitory ras mutant specifically blocked antigen receptor agonism, indicating that ras activity is required for antigen receptor signaling. |
| T6 |
720-872 |
Sentence |
denotes |
A dominant inhibitory ras mutant specifically blocked antigen receptor agonism, indicating that ras activity is required for antigen receptor signaling. |
| T7 |
873-1006 |
Sentence |
denotes |
In addition, an inhibitor of PKC blocked both activated ras and phorbol ester stimulation, suggesting a role for ras upstream of PKC. |
| T7 |
873-1006 |
Sentence |
denotes |
In addition, an inhibitor of PKC blocked both activated ras and phorbol ester stimulation, suggesting a role for ras upstream of PKC. |