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PubMed:8383844 JSONTXT 6 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-186 Sentence denotes Competition between transcription factors HNF1 and HNF3, and alternative cell-specific activation by DBP and C/EBP contribute to the regulation of the liver-specific aldolase B promoter.
T1 0-186 Sentence denotes Competition between transcription factors HNF1 and HNF3, and alternative cell-specific activation by DBP and C/EBP contribute to the regulation of the liver-specific aldolase B promoter.
TextSentencer_T2 187-338 Sentence denotes The aldolase B proximal promoter is controlled by at least five elements spanning from -190 to -103 bp with respect to the start site of transcription.
T2 187-338 Sentence denotes The aldolase B proximal promoter is controlled by at least five elements spanning from -190 to -103 bp with respect to the start site of transcription.
TextSentencer_T3 339-575 Sentence denotes From 5' to 3', we found: a negative DE element, an activating C/EBP-DBP binding site, a CCAAT box binding NFY that seems to play a negative role, and an activating element consisting of two overlapping binding sites for HNF-1 and HNF-3.
T3 339-575 Sentence denotes From 5' to 3', we found: a negative DE element, an activating C/EBP-DBP binding site, a CCAAT box binding NFY that seems to play a negative role, and an activating element consisting of two overlapping binding sites for HNF-1 and HNF-3.
TextSentencer_T4 576-743 Sentence denotes Contransfection experiments of aldolase B/CAT constructs and of expression vectors for different transcription factors were carried out in human hepatoma Hep G2 cells.
T4 576-743 Sentence denotes Contransfection experiments of aldolase B/CAT constructs and of expression vectors for different transcription factors were carried out in human hepatoma Hep G2 cells.
TextSentencer_T5 744-920 Sentence denotes We found that DBP and HNF-1 are strong transactivators of the aldolase B promoter while C/EBP and vHNF-1 are only weak activators and HNF-3 alone does not modify such activity.
T5 744-920 Sentence denotes We found that DBP and HNF-1 are strong transactivators of the aldolase B promoter while C/EBP and vHNF-1 are only weak activators and HNF-3 alone does not modify such activity.
TextSentencer_T6 921-1067 Sentence denotes Deletion of the distal negative element results in a similar transactivation by C/EBP and DBP, enhanced for the former and reduced for the latter.
T6 921-1067 Sentence denotes Deletion of the distal negative element results in a similar transactivation by C/EBP and DBP, enhanced for the former and reduced for the latter.
TextSentencer_T7 1068-1172 Sentence denotes In hepatocytes in primary culture, the strong transactivator is C/EBP while DBP is essentially inactive.
T7 1068-1172 Sentence denotes In hepatocytes in primary culture, the strong transactivator is C/EBP while DBP is essentially inactive.
TextSentencer_T8 1173-1321 Sentence denotes This tissue-specificity of C/EBP and DBP action could depend on interaction with tissue-specific proteins bound to a neighbouring site, probably DE.
T8 1173-1321 Sentence denotes This tissue-specificity of C/EBP and DBP action could depend on interaction with tissue-specific proteins bound to a neighbouring site, probably DE.
TextSentencer_T9 1322-1403 Sentence denotes Finally, HNF3 behaves as a very strong anti-activator of the aldolase B promoter.
T9 1322-1403 Sentence denotes Finally, HNF3 behaves as a very strong anti-activator of the aldolase B promoter.
TextSentencer_T10 1404-1503 Sentence denotes It competitively antagonizes transactivation by HNF-1 and non-competitively transactivation by DBP.
T10 1404-1503 Sentence denotes It competitively antagonizes transactivation by HNF-1 and non-competitively transactivation by DBP.
TextSentencer_T11 1504-1654 Sentence denotes This negative effect of HNF-3 and tissue-specificity of the transactivation potential of DBP and C/EBP are unique features of the aldolase B promoter.
T11 1504-1654 Sentence denotes This negative effect of HNF-3 and tissue-specificity of the transactivation potential of DBP and C/EBP are unique features of the aldolase B promoter.