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PubMed:8376413 JSONTXT 20 Projects

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Id Subject Object Predicate Lexical cue
T1 0-62 Sentence denotes Structural prerequisites for serum amyloid A fibril formation.
T1 0-62 Sentence denotes Structural prerequisites for serum amyloid A fibril formation.
T2 63-199 Sentence denotes Most studies of experimental amyloid A protein (AA) amyloidosis in mice have been performed in type A mice with BALB/c as the prototype.
T2 63-199 Sentence denotes Most studies of experimental amyloid A protein (AA) amyloidosis in mice have been performed in type A mice with BALB/c as the prototype.
T3 200-321 Sentence denotes In these mice the products of two genes, SAA1 and SAA2, are the major apo-SAA isoforms on high density lipoprotein (HDL).
T3 200-321 Sentence denotes In these mice the products of two genes, SAA1 and SAA2, are the major apo-SAA isoforms on high density lipoprotein (HDL).
T4 322-444 Sentence denotes Of these two isoforms, that differ at nine amino acids, only apo-SAA2 is rapidly cleared and deposited as amyloid fibrils.
T4 322-444 Sentence denotes Of these two isoforms, that differ at nine amino acids, only apo-SAA2 is rapidly cleared and deposited as amyloid fibrils.
T5 445-529 Sentence denotes No mouse strain has ever been shown to be completely resistant to amyloid induction.
T5 445-529 Sentence denotes No mouse strain has ever been shown to be completely resistant to amyloid induction.
T6 530-613 Sentence denotes We have found the CE/J mouse strain to be exceedingly resistant to amyloidogenesis.
T6 530-613 Sentence denotes We have found the CE/J mouse strain to be exceedingly resistant to amyloidogenesis.
T7 614-755 Sentence denotes Data indicate that this resistance is not due to a lack of apo-SAA synthesis but rather resides in the unique apo-SAA isoform in this strain.
T7 614-755 Sentence denotes Data indicate that this resistance is not due to a lack of apo-SAA synthesis but rather resides in the unique apo-SAA isoform in this strain.
T8 756-841 Sentence denotes CE/J mice have a single major apo-SAA isoform (pI 6.15) the product of a single gene.
T8 756-841 Sentence denotes CE/J mice have a single major apo-SAA isoform (pI 6.15) the product of a single gene.
T9 842-963 Sentence denotes This is a hybrid molecule with features of both apo-SAA1 and apo-SAA2, differing from the latter at only six amino acids.
T9 842-963 Sentence denotes This is a hybrid molecule with features of both apo-SAA1 and apo-SAA2, differing from the latter at only six amino acids.
T10 964-1219 Sentence denotes When CD studies were performed to explore the structural relationship of this isoform to apo-SAA1 and apo-SAA2, we found that when bound to heparan sulfate proteoglycan the CE/J pI 6.15 isoform fails to undergo the beta-sheet folding typical for apo-SAA2.
T10 964-1219 Sentence denotes When CD studies were performed to explore the structural relationship of this isoform to apo-SAA1 and apo-SAA2, we found that when bound to heparan sulfate proteoglycan the CE/J pI 6.15 isoform fails to undergo the beta-sheet folding typical for apo-SAA2.
T11 1220-1345 Sentence denotes This evidence suggests that the folding effect of heparan sulfate proteoglycan on apo-SAA2 is important in amyloid formation.
T11 1220-1345 Sentence denotes This evidence suggests that the folding effect of heparan sulfate proteoglycan on apo-SAA2 is important in amyloid formation.