Id |
Subject |
Object |
Predicate |
Lexical cue |
T1 |
0-75 |
Sentence |
denotes |
Molecular cloning and expression of murine liver soluble epoxide hydrolase. |
T1 |
0-75 |
Sentence |
denotes |
Molecular cloning and expression of murine liver soluble epoxide hydrolase. |
T2 |
76-205 |
Sentence |
denotes |
A clofibrate-induced mouse liver cDNA library was prepared and used to isolate the coding sequence for soluble epoxide hydrolase. |
T2 |
76-205 |
Sentence |
denotes |
A clofibrate-induced mouse liver cDNA library was prepared and used to isolate the coding sequence for soluble epoxide hydrolase. |
T3 |
206-324 |
Sentence |
denotes |
A 1668-base pair (bp) clone was isolated and found to contain a 1269-bp open reading frame coding for 423 amino acids. |
T3 |
206-324 |
Sentence |
denotes |
A 1668-base pair (bp) clone was isolated and found to contain a 1269-bp open reading frame coding for 423 amino acids. |
T4 |
325-428 |
Sentence |
denotes |
Subsequent RNA polymerase chain reaction resulted in the isolation of 396 bp of additional 5'-sequence. |
T4 |
325-428 |
Sentence |
denotes |
Subsequent RNA polymerase chain reaction resulted in the isolation of 396 bp of additional 5'-sequence. |
T5 |
429-706 |
Sentence |
denotes |
Translation of the resulting 1659-bp open reading frame produced a 553-residue protein (62,527 Da) containing deduced peptide segments that matched the amino acid sequences of six peptide fragments isolated previously from CNBr digests of pure murine soluble epoxide hydrolase. |
T5 |
429-706 |
Sentence |
denotes |
Translation of the resulting 1659-bp open reading frame produced a 553-residue protein (62,527 Da) containing deduced peptide segments that matched the amino acid sequences of six peptide fragments isolated previously from CNBr digests of pure murine soluble epoxide hydrolase. |
T6 |
707-817 |
Sentence |
denotes |
Neither the DNA nor the protein sequence showed significant similarity to other currently published sequences. |
T6 |
707-817 |
Sentence |
denotes |
Neither the DNA nor the protein sequence showed significant similarity to other currently published sequences. |
T7 |
818-935 |
Sentence |
denotes |
Structural analysis of the soluble epoxide hydrolase coding region suggested at least one potential regulatory motif. |
T7 |
818-935 |
Sentence |
denotes |
Structural analysis of the soluble epoxide hydrolase coding region suggested at least one potential regulatory motif. |
T8 |
936-1187 |
Sentence |
denotes |
Expression of the composite cDNA in COS-7 cells resulted in a 5-10-fold increase in soluble epoxide hydrolase activity and a similar increase in soluble epoxide hydrolase protein amount compared to mock-transfected or vector control-transfected cells. |
T8 |
936-1187 |
Sentence |
denotes |
Expression of the composite cDNA in COS-7 cells resulted in a 5-10-fold increase in soluble epoxide hydrolase activity and a similar increase in soluble epoxide hydrolase protein amount compared to mock-transfected or vector control-transfected cells. |
T9 |
1188-1350 |
Sentence |
denotes |
Treatment of C57BL/6J mice with clofibrate led to an approximately 4-fold increase in both soluble epoxide hydrolase enzyme activity and steady-state mRNA levels. |
T9 |
1188-1350 |
Sentence |
denotes |
Treatment of C57BL/6J mice with clofibrate led to an approximately 4-fold increase in both soluble epoxide hydrolase enzyme activity and steady-state mRNA levels. |