> top > projects > sentences > docs > PubMed:8175802 > annotations
sentences Home  

PubMed:8175802 JSONTXT 27 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
T1 0-65 Sentence denotes Mutation in the COL2A1 gene in a patient with hypochondrogenesis.
T1 0-65 Sentence denotes Mutation in the COL2A1 gene in a patient with hypochondrogenesis.
T2 66-177 Sentence denotes Expression of mutated COL2A1 gene is accompanied by expression of genes for type I procollagen in chondrocytes.
T2 66-177 Sentence denotes Expression of mutated COL2A1 gene is accompanied by expression of genes for type I procollagen in chondrocytes.
T3 178-278 Sentence denotes A new dominant mutation in the COL2A1 gene was found in a 38-week-old fetus with hypochondrogenesis.
T3 178-278 Sentence denotes A new dominant mutation in the COL2A1 gene was found in a 38-week-old fetus with hypochondrogenesis.
T4 279-449 Sentence denotes Denaturing gradient gel electrophoresis was used to analyze all 44 exons coding for the triple-helical domain of COL2A1 gene and the corresponding exon-intron boundaries.
T4 279-449 Sentence denotes Denaturing gradient gel electrophoresis was used to analyze all 44 exons coding for the triple-helical domain of COL2A1 gene and the corresponding exon-intron boundaries.
T5 450-509 Sentence denotes The technique detected a new sequence variation in exon 35.
T5 450-509 Sentence denotes The technique detected a new sequence variation in exon 35.
T6 510-644 Sentence denotes Sequencing of exon 35 demonstrated a single base mutation that converted the codon for glycine at position 604 to a codon for alanine.
T6 510-644 Sentence denotes Sequencing of exon 35 demonstrated a single base mutation that converted the codon for glycine at position 604 to a codon for alanine.
T7 645-866 Sentence denotes Electrophoresis of pepsin-digested collagen extracted from the diseased cartilage showed a doublet band of the alpha 1(II) chain of type II collagen and the presence of alpha 1(I) and alpha 2(I) chains of type I collagen.
T7 645-866 Sentence denotes Electrophoresis of pepsin-digested collagen extracted from the diseased cartilage showed a doublet band of the alpha 1(II) chain of type II collagen and the presence of alpha 1(I) and alpha 2(I) chains of type I collagen.
T8 867-1073 Sentence denotes Two-dimensional analysis of cyanogen bromide peptides from the type II collagen revealed post-translational overmodification of peptides CB12, CB11, CB8, and CB10.5, whereas peptide CB9.7 migrated normally.
T8 867-1073 Sentence denotes Two-dimensional analysis of cyanogen bromide peptides from the type II collagen revealed post-translational overmodification of peptides CB12, CB11, CB8, and CB10.5, whereas peptide CB9.7 migrated normally.
T9 1074-1181 Sentence denotes Microscopic examination of cartilage showed that the mutation altered the organization of the growth plate.
T9 1074-1181 Sentence denotes Microscopic examination of cartilage showed that the mutation altered the organization of the growth plate.
T10 1182-1268 Sentence denotes Also, articular chondrocytes contained large cisternae of rough endoplasmic reticulum.
T10 1182-1268 Sentence denotes Also, articular chondrocytes contained large cisternae of rough endoplasmic reticulum.
T11 1269-1408 Sentence denotes The density of the extracellular matrix was reduced, and the intensity of the staining with an antibody to type II collagen was diminished.
T11 1269-1408 Sentence denotes The density of the extracellular matrix was reduced, and the intensity of the staining with an antibody to type II collagen was diminished.
T12 1409-1494 Sentence denotes In contrast, a significant staining with an antibody to type I collagen was observed.
T12 1409-1494 Sentence denotes In contrast, a significant staining with an antibody to type I collagen was observed.
T13 1495-1629 Sentence denotes In situ hybridization with cRNA probes revealed a significant level of alpha 1(I) mRNA in the cytoplasm of the patient's chondrocytes.
T13 1495-1629 Sentence denotes In situ hybridization with cRNA probes revealed a significant level of alpha 1(I) mRNA in the cytoplasm of the patient's chondrocytes.
T14 1630-1700 Sentence denotes The signal for alpha 1(II) mRNA was about the same in control samples.
T14 1630-1700 Sentence denotes The signal for alpha 1(II) mRNA was about the same in control samples.
T15 1701-1854 Sentence denotes The results indicated, therefore, that the genes for both type I and type II procollagens were simultaneously expressed in chondrocytes from the patient.
T15 1701-1854 Sentence denotes The results indicated, therefore, that the genes for both type I and type II procollagens were simultaneously expressed in chondrocytes from the patient.