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Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
T1 0-62 Sentence denotes Lactosylceramide beta-galactosidase in human sphingolipidoses.
T1 0-62 Sentence denotes Lactosylceramide beta-galactosidase in human sphingolipidoses.
T2 63-109 Sentence denotes Evidence for two genetically distinct enzymes.
T2 63-109 Sentence denotes Evidence for two genetically distinct enzymes.
T3 110-365 Sentence denotes In view of recent conflicting reports from two laboratories, activities of lactosylceramide beta-galactosidase were reinvestigated in detail in brains and livers of normal individuals and of patients with globoid cell leukodystrophy or GM1-gangliosidosis.
T3 110-365 Sentence denotes In view of recent conflicting reports from two laboratories, activities of lactosylceramide beta-galactosidase were reinvestigated in detail in brains and livers of normal individuals and of patients with globoid cell leukodystrophy or GM1-gangliosidosis.
T4 366-523 Sentence denotes Both sets of the apparently totally contradictory results were readily reproduced simply by using the different assay systems of the respective laboratories.
T4 366-523 Sentence denotes Both sets of the apparently totally contradictory results were readily reproduced simply by using the different assay systems of the respective laboratories.
T5 524-813 Sentence denotes With our own assay system, hepatic lactosylceramide beta-galactosidase appeared deficient only in Gm1-gangliosidosis, while it appeared deficient only in globoid cell leukodystrophy when the assay system of Wenger et al. (Wenger, D.A., Sattler, M., Clark, D., and McKelvey, H. (1974) Clin.
T5 524-813 Sentence denotes With our own assay system, hepatic lactosylceramide beta-galactosidase appeared deficient only in Gm1-gangliosidosis, while it appeared deficient only in globoid cell leukodystrophy when the assay system of Wenger et al. (Wenger, D.A., Sattler, M., Clark, D., and McKelvey, H. (1974) Clin.
T6 814-819 Sentence denotes Chim.
T6 814-819 Sentence denotes Chim.
T7 820-847 Sentence denotes Acta 56, 199-206) was used.
T7 820-847 Sentence denotes Acta 56, 199-206) was used.
T8 848-978 Sentence denotes Analyses of individual constitutents in the two assay systems revealed their complex effects on measured activities of the enzyme.
T8 848-978 Sentence denotes Analyses of individual constitutents in the two assay systems revealed their complex effects on measured activities of the enzyme.
T9 979-1096 Sentence denotes The findings were strongly indicative of the existence of two genetically distinct lactosylceramide-cleaving enzymes.
T9 979-1096 Sentence denotes The findings were strongly indicative of the existence of two genetically distinct lactosylceramide-cleaving enzymes.
T10 1097-1305 Sentence denotes One enzyme (lactosylceramidase I) may be identical with galactosylceramide betal-galactosidase, and the other (lactosylceramidase II) is closely related to nonspecific 4-methylumbelliferyl beta-galactosidase.
T10 1097-1305 Sentence denotes One enzyme (lactosylceramidase I) may be identical with galactosylceramide betal-galactosidase, and the other (lactosylceramidase II) is closely related to nonspecific 4-methylumbelliferyl beta-galactosidase.
T11 1306-1427 Sentence denotes Normal human brain contains mostly lactosylceramidase I, while normal liver contains predominantly lactosylceramidase II.
T11 1306-1427 Sentence denotes Normal human brain contains mostly lactosylceramidase I, while normal liver contains predominantly lactosylceramidase II.
T12 1428-1549 Sentence denotes Lactosylceramidase I is genetically lacking globoid cell leukodystrophy, and lactosylceramidase II in GM1-gangliosidosis.
T12 1428-1549 Sentence denotes Lactosylceramidase I is genetically lacking globoid cell leukodystrophy, and lactosylceramidase II in GM1-gangliosidosis.
T13 1550-1687 Sentence denotes Lactosylceramidase I is activated by either pure or crude taurocholate and by oleic acid and is only slightly activated by chloride ions.
T13 1550-1687 Sentence denotes Lactosylceramidase I is activated by either pure or crude taurocholate and by oleic acid and is only slightly activated by chloride ions.
T14 1688-1774 Sentence denotes Lactosylceramidase II is activated by crude taurocholate but not by pure taurocholate.
T14 1688-1774 Sentence denotes Lactosylceramidase II is activated by crude taurocholate but not by pure taurocholate.
T15 1775-1877 Sentence denotes As activators, oleic acid is less effective and chloride more effective than for lactosylceramidase I.
T15 1775-1877 Sentence denotes As activators, oleic acid is less effective and chloride more effective than for lactosylceramidase I.
T16 1878-2014 Sentence denotes Citrate-phosphate buffer is more favorable to lactosylceramidase I than citrate buffer, while lactosylceramidase II responds in reverse.
T16 1878-2014 Sentence denotes Citrate-phosphate buffer is more favorable to lactosylceramidase I than citrate buffer, while lactosylceramidase II responds in reverse.
T17 2015-2229 Sentence denotes The standard assay system used by Wenger et al. determines almost exclusively lactosylceramidase I, while our own standard system is optimal for lactosylceramidase II and is less favorable for lactosylceramidase I.
T17 2015-2229 Sentence denotes The standard assay system used by Wenger et al. determines almost exclusively lactosylceramidase I, while our own standard system is optimal for lactosylceramidase II and is less favorable for lactosylceramidase I.
T18 2230-2492 Sentence denotes With a highly purified human hepatic beta-galactosidase preparation, exxentially free of galactosylceramide beta-galactosidase activity, lactosylceramide-cleaving activity determined by the Wenger system was less than 2 per cent of that determined by our system.
T18 2230-2492 Sentence denotes With a highly purified human hepatic beta-galactosidase preparation, exxentially free of galactosylceramide beta-galactosidase activity, lactosylceramide-cleaving activity determined by the Wenger system was less than 2 per cent of that determined by our system.
T19 2493-2711 Sentence denotes If lactosylceramide beta-balactosidase assays are to be used for diagnosis of globoid cell leukodystrophy, it is absolutely essential to use an appropriate assay system in order to avoid errors of serious consequences.
T19 2493-2711 Sentence denotes If lactosylceramide beta-balactosidase assays are to be used for diagnosis of globoid cell leukodystrophy, it is absolutely essential to use an appropriate assay system in order to avoid errors of serious consequences.