| Id |
Subject |
Object |
Predicate |
Lexical cue |
| TextSentencer_T1 |
0-89 |
Sentence |
denotes |
EGF modulation of the ras-related rhoB gene expression in human breast-cancer cell lines. |
| T1 |
0-89 |
Sentence |
denotes |
EGF modulation of the ras-related rhoB gene expression in human breast-cancer cell lines. |
| TextSentencer_T2 |
90-328 |
Sentence |
denotes |
The mRNA levels of the ras-related human rhoA, rhoB and rhoC genes were studied in human breast-cancer cell lines (HBCal), and in normal and immortalized mammary epithelial cells (HMEC) by Northern blot analysis and in situ hybridization. |
| T2 |
90-328 |
Sentence |
denotes |
The mRNA levels of the ras-related human rhoA, rhoB and rhoC genes were studied in human breast-cancer cell lines (HBCal), and in normal and immortalized mammary epithelial cells (HMEC) by Northern blot analysis and in situ hybridization. |
| TextSentencer_T3 |
329-460 |
Sentence |
denotes |
In contrast to the ubiquitous rhoA and rhoC gene expression, dramatic variations in the mRNA level of the rhoB gene were evidenced. |
| T3 |
329-460 |
Sentence |
denotes |
In contrast to the ubiquitous rhoA and rhoC gene expression, dramatic variations in the mRNA level of the rhoB gene were evidenced. |
| TextSentencer_T4 |
461-593 |
Sentence |
denotes |
The rhoB mRNA level appeared to be inversely correlated to the amounts of the epidermal-growth-factor(EGF) receptors in these cells. |
| T4 |
461-593 |
Sentence |
denotes |
The rhoB mRNA level appeared to be inversely correlated to the amounts of the epidermal-growth-factor(EGF) receptors in these cells. |
| TextSentencer_T5 |
594-850 |
Sentence |
denotes |
The rhoB transcripts were detected at high levels in ZR75-1, MCF7, HSL 53, HSL 59, HSL 90, T47D and SKBR3 HBCal, at hardly detectable levels in BT 20, MDA-MB 231 and H466B HBCal and at intermediate levels in normal and immortalized breast epithelial cells. |
| T5 |
594-850 |
Sentence |
denotes |
The rhoB transcripts were detected at high levels in ZR75-1, MCF7, HSL 53, HSL 59, HSL 90, T47D and SKBR3 HBCal, at hardly detectable levels in BT 20, MDA-MB 231 and H466B HBCal and at intermediate levels in normal and immortalized breast epithelial cells. |
| TextSentencer_T6 |
851-1008 |
Sentence |
denotes |
Rapid and transient induction of the rhoB transcription was observed after EGF treatment in serum-deprived MDA-MB231, T47D and immortalized epithelial cells. |
| T6 |
851-1008 |
Sentence |
denotes |
Rapid and transient induction of the rhoB transcription was observed after EGF treatment in serum-deprived MDA-MB231, T47D and immortalized epithelial cells. |
| TextSentencer_T7 |
1009-1117 |
Sentence |
denotes |
In contrast, no modulation of rhoB expression by EGF could be objectified in the MCF7 and ZR75-1 cell lines. |
| T7 |
1009-1117 |
Sentence |
denotes |
In contrast, no modulation of rhoB expression by EGF could be objectified in the MCF7 and ZR75-1 cell lines. |
| TextSentencer_T8 |
1118-1327 |
Sentence |
denotes |
Yet a normal function of EGF receptors was evidenced, since the immediate early gene c-fos was rapidly induced, suggesting a constitutive expression of rhoB in these cell lines bypassing the regulation by EGF. |
| T8 |
1118-1327 |
Sentence |
denotes |
Yet a normal function of EGF receptors was evidenced, since the immediate early gene c-fos was rapidly induced, suggesting a constitutive expression of rhoB in these cell lines bypassing the regulation by EGF. |
| TextSentencer_T9 |
1328-1470 |
Sentence |
denotes |
In human mammary epithelial cells, rhoB mRNA is rapidly and transiently induced with EGF concentrations known to stimulate cell proliferation. |
| T9 |
1328-1470 |
Sentence |
denotes |
In human mammary epithelial cells, rhoB mRNA is rapidly and transiently induced with EGF concentrations known to stimulate cell proliferation. |
| TextSentencer_T10 |
1471-1672 |
Sentence |
denotes |
This suggests that the rhoB product might be involved in a cascade that initiates or promotes cell proliferation, and plays an important role in EGF-stimulated growth of breast normal and cancer cells. |
| T10 |
1471-1672 |
Sentence |
denotes |
This suggests that the rhoB product might be involved in a cascade that initiates or promotes cell proliferation, and plays an important role in EGF-stimulated growth of breast normal and cancer cells. |