| Id |
Subject |
Object |
Predicate |
Lexical cue |
| TextSentencer_T1 |
0-59 |
Sentence |
denotes |
Variations in transcription-repair coupling in mouse cells. |
| T1 |
0-59 |
Sentence |
denotes |
Variations in transcription-repair coupling in mouse cells. |
| TextSentencer_T2 |
60-187 |
Sentence |
denotes |
Formation and repair of UV-induced cyclobutane pyrimidine dimers (CPDs) was examined in three different genes in mouse L cells: |
| T2 |
60-187 |
Sentence |
denotes |
Formation and repair of UV-induced cyclobutane pyrimidine dimers (CPDs) was examined in three different genes in mouse L cells: |
| TextSentencer_T3 |
188-443 |
Sentence |
denotes |
1) a stably integrated insert (called LTL), consisting of a herpes simplex virus thymidine kinase gene (tk) fused to a hormone inducible promotor (LTR); 2) the constitutively expressed proto-oncogene c-abl; and 3) the inactive immunoglobulin J chain gene. |
| T3 |
188-443 |
Sentence |
denotes |
1) a stably integrated insert (called LTL), consisting of a herpes simplex virus thymidine kinase gene (tk) fused to a hormone inducible promotor (LTR); 2) the constitutively expressed proto-oncogene c-abl; and 3) the inactive immunoglobulin J chain gene. |
| TextSentencer_T4 |
444-511 |
Sentence |
denotes |
Transcription of the tk gene is induced > 50-fold by dexamethasone. |
| T4 |
444-511 |
Sentence |
denotes |
Transcription of the tk gene is induced > 50-fold by dexamethasone. |
| TextSentencer_T5 |
512-708 |
Sentence |
denotes |
There is a nonuniform distribution of CPDs in LTL DNA irradiated in vitro, being 4-fold higher in the LTR than in the tk gene, indicating the LTR may be damaged preferentially in irradiated cells. |
| T5 |
512-708 |
Sentence |
denotes |
There is a nonuniform distribution of CPDs in LTL DNA irradiated in vitro, being 4-fold higher in the LTR than in the tk gene, indicating the LTR may be damaged preferentially in irradiated cells. |
| TextSentencer_T6 |
709-830 |
Sentence |
denotes |
Repair of CPDs occurs efficiently in both strands of LTL and is unaffected by hormone induction of tk gene transcription. |
| T6 |
709-830 |
Sentence |
denotes |
Repair of CPDs occurs efficiently in both strands of LTL and is unaffected by hormone induction of tk gene transcription. |
| TextSentencer_T7 |
831-932 |
Sentence |
denotes |
Transcription of tk mRNA is very sensitive to UV damage and follows single hit kinetics with UV dose. |
| T7 |
831-932 |
Sentence |
denotes |
Transcription of tk mRNA is very sensitive to UV damage and follows single hit kinetics with UV dose. |
| TextSentencer_T8 |
933-1007 |
Sentence |
denotes |
Furthermore, tk mRNA expression rapidly recovers during repair incubation. |
| T8 |
933-1007 |
Sentence |
denotes |
Furthermore, tk mRNA expression rapidly recovers during repair incubation. |
| TextSentencer_T9 |
1008-1243 |
Sentence |
denotes |
Transcription-coupled repair occurs in these cells, however, since only the transcribed strand of c-abl is efficiently repaired of CPDs; the non-transcribed strand as well as both strands of the J chain gene are inefficiently repaired. |
| T9 |
1008-1243 |
Sentence |
denotes |
Transcription-coupled repair occurs in these cells, however, since only the transcribed strand of c-abl is efficiently repaired of CPDs; the non-transcribed strand as well as both strands of the J chain gene are inefficiently repaired. |
| TextSentencer_T10 |
1244-1397 |
Sentence |
denotes |
Thus, repair in the LTL construct may reflect a lack of transcription-coupled repair in either the LTR promotor or the LTL insertion region of chromatin. |
| T10 |
1244-1397 |
Sentence |
denotes |
Thus, repair in the LTL construct may reflect a lack of transcription-coupled repair in either the LTR promotor or the LTL insertion region of chromatin. |