| Id |
Subject |
Object |
Predicate |
Lexical cue |
| TextSentencer_T1 |
0-66 |
Sentence |
denotes |
Hereditary deficiency of the fifth component of complement in man. |
| T1 |
0-66 |
Sentence |
denotes |
Hereditary deficiency of the fifth component of complement in man. |
| TextSentencer_T2 |
67-70 |
Sentence |
denotes |
II. |
| T2 |
67-70 |
Sentence |
denotes |
II. |
| TextSentencer_T3 |
71-121 |
Sentence |
denotes |
Biological properties of C5-deficient human serum. |
| T3 |
71-121 |
Sentence |
denotes |
Biological properties of C5-deficient human serum. |
| TextSentencer_T4 |
122-263 |
Sentence |
denotes |
The first known human kindred with hereditary deficiency of the fifth component of complement (C5) was documented in the accompanying report. |
| T4 |
122-263 |
Sentence |
denotes |
The first known human kindred with hereditary deficiency of the fifth component of complement (C5) was documented in the accompanying report. |
| TextSentencer_T5 |
264-401 |
Sentence |
denotes |
This study examines several biological properties of C5-deficient (C5D) human serum, particularly sera obtained from two C5D homozygotes. |
| T5 |
264-401 |
Sentence |
denotes |
This study examines several biological properties of C5-deficient (C5D) human serum, particularly sera obtained from two C5D homozygotes. |
| TextSentencer_T6 |
402-543 |
Sentence |
denotes |
The proband, who has inactive systemic lupus erythematosus is completely lacking C5, while her healthy half-sister has 1-2% of normal levels. |
| T6 |
402-543 |
Sentence |
denotes |
The proband, who has inactive systemic lupus erythematosus is completely lacking C5, while her healthy half-sister has 1-2% of normal levels. |
| TextSentencer_T7 |
544-739 |
Sentence |
denotes |
Both sera were severely impaired in their ability to generate chemotactic activity for normal human neutrophils upon incubation with aggregated human gamma-globulin or Escherichia coli endotoxin. |
| T7 |
544-739 |
Sentence |
denotes |
Both sera were severely impaired in their ability to generate chemotactic activity for normal human neutrophils upon incubation with aggregated human gamma-globulin or Escherichia coli endotoxin. |
| TextSentencer_T8 |
740-919 |
Sentence |
denotes |
This function was fully restored in the sibling's serum, and substantially improved in the proband's serum, by addition of highly purified human C5 to normal serum concentrations. |
| T8 |
740-919 |
Sentence |
denotes |
This function was fully restored in the sibling's serum, and substantially improved in the proband's serum, by addition of highly purified human C5 to normal serum concentrations. |
| TextSentencer_T9 |
920-1033 |
Sentence |
denotes |
Sera from eight family members who were apparently heterozygous for C5 deficiency gave normal chemotactic scores. |
| T9 |
920-1033 |
Sentence |
denotes |
Sera from eight family members who were apparently heterozygous for C5 deficiency gave normal chemotactic scores. |
| TextSentencer_T10 |
1034-1190 |
Sentence |
denotes |
The ability of C5D serum to opsonize Saccharomyces cerevisiae (baker's yeast) or Candida albicans for ingestion by normal neutrophils was completely normal. |
| T10 |
1034-1190 |
Sentence |
denotes |
The ability of C5D serum to opsonize Saccharomyces cerevisiae (baker's yeast) or Candida albicans for ingestion by normal neutrophils was completely normal. |
| TextSentencer_T11 |
1191-1310 |
Sentence |
denotes |
In addition, C5D serum was capable of promoting normal phagocytosis and intracellular killing of Staphylococcus aureus. |
| T11 |
1191-1310 |
Sentence |
denotes |
In addition, C5D serum was capable of promoting normal phagocytosis and intracellular killing of Staphylococcus aureus. |
| TextSentencer_T12 |
1311-1582 |
Sentence |
denotes |
The proband's serum was incapable of mediating lysis of erythrocytes from a patient with paroxysmal nocturnal hemoglobinuria in both the sucrose hemolysia and acid hemolysis tests, and also lacked bactericidal activity against sensitized or unsensitized Salmonella typhi. |
| T12 |
1311-1582 |
Sentence |
denotes |
The proband's serum was incapable of mediating lysis of erythrocytes from a patient with paroxysmal nocturnal hemoglobinuria in both the sucrose hemolysia and acid hemolysis tests, and also lacked bactericidal activity against sensitized or unsensitized Salmonella typhi. |
| TextSentencer_T13 |
1583-1734 |
Sentence |
denotes |
The sibling's serum, containing only 1-2% of normal C5, effectively lysed S. typhi, but only at eightfold lower serum dilutions as compared to normals. |
| T13 |
1583-1734 |
Sentence |
denotes |
The sibling's serum, containing only 1-2% of normal C5, effectively lysed S. typhi, but only at eightfold lower serum dilutions as compared to normals. |
| TextSentencer_T14 |
1735-1957 |
Sentence |
denotes |
These findings underscore the critical role of C5 in the generation of chemotactic activity and in cytolytic reactions, as opposed to a nonobligatory or minimal role in opsonization, at least for the organisms under study. |
| T14 |
1735-1957 |
Sentence |
denotes |
These findings underscore the critical role of C5 in the generation of chemotactic activity and in cytolytic reactions, as opposed to a nonobligatory or minimal role in opsonization, at least for the organisms under study. |