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PubMed:7759548 JSONTXT 29 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
T1 0-115 Sentence denotes Identification of two novel regulatory elements within the 5'-untranslated region of the human A gamma-globin gene.
T1 0-115 Sentence denotes Identification of two novel regulatory elements within the 5'-untranslated region of the human A gamma-globin gene.
T2 116-366 Sentence denotes Interaction between the stage selector element (SSE) in the proximal gamma-globin promoter and hypersensitivity site 2 in the locus control region partly mediates the competitive silencing of the beta-globin promoter in the fetal developmental stage.
T2 116-366 Sentence denotes Interaction between the stage selector element (SSE) in the proximal gamma-globin promoter and hypersensitivity site 2 in the locus control region partly mediates the competitive silencing of the beta-globin promoter in the fetal developmental stage.
T3 367-535 Sentence denotes We have now demonstrated that a second SSE-like element in the 5'-untranslated region of the gamma-gene also contributes to this competitive silencing of the beta-gene.
T3 367-535 Sentence denotes We have now demonstrated that a second SSE-like element in the 5'-untranslated region of the gamma-gene also contributes to this competitive silencing of the beta-gene.
T4 536-812 Sentence denotes Utilizing transient transfection assays in the fetal erythroid cell line, K562, we have shown that the core enhancer of hypersensitivity site 2 can preferentially interact with the proximal gamma-promoter in the absence of the SSE, completely silencing a linked beta-promoter.
T4 536-812 Sentence denotes Utilizing transient transfection assays in the fetal erythroid cell line, K562, we have shown that the core enhancer of hypersensitivity site 2 can preferentially interact with the proximal gamma-promoter in the absence of the SSE, completely silencing a linked beta-promoter.
T5 813-942 Sentence denotes Mutation of a 20-base pair sequence of the gamma-gene 5'-untranslated region (UTR) led to derepression of beta-promoter activity.
T5 813-942 Sentence denotes Mutation of a 20-base pair sequence of the gamma-gene 5'-untranslated region (UTR) led to derepression of beta-promoter activity.
T6 943-1067 Sentence denotes A marked activation of gamma-promoter activity was also observed with this mutation, suggesting the presence of a repressor.
T6 943-1067 Sentence denotes A marked activation of gamma-promoter activity was also observed with this mutation, suggesting the presence of a repressor.
T7 1068-1147 Sentence denotes Fine mutagenesis dissected these activities to different regions of the 5'-UTR.
T7 1068-1147 Sentence denotes Fine mutagenesis dissected these activities to different regions of the 5'-UTR.
T8 1148-1237 Sentence denotes The stage selector activity was localized to a region centered on nucleotides +13 to +15.
T8 1148-1237 Sentence denotes The stage selector activity was localized to a region centered on nucleotides +13 to +15.
T9 1238-1354 Sentence denotes Electromobility shift assays utilizing this sequence demonstrated binding of a fetal and erythroid-specific protein.
T9 1238-1354 Sentence denotes Electromobility shift assays utilizing this sequence demonstrated binding of a fetal and erythroid-specific protein.
T10 1355-1539 Sentence denotes The repressor activity of the 5'-UTR was localized to tandem GATA-like sites, which appear to bind a complex of two proteins, one of which is the erythroid transcription factor GATA-1.
T10 1355-1539 Sentence denotes The repressor activity of the 5'-UTR was localized to tandem GATA-like sites, which appear to bind a complex of two proteins, one of which is the erythroid transcription factor GATA-1.
T11 1540-1691 Sentence denotes These results indicate that the 5'-UTR of the gamma-gene contains sequences that may be important for its transcriptional and developmental regulation.
T11 1540-1691 Sentence denotes These results indicate that the 5'-UTR of the gamma-gene contains sequences that may be important for its transcriptional and developmental regulation.