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Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-119 Sentence denotes Post-translational modifications distinguish cell surface from Golgi-retained beta 1,4 galactosyltransferase molecules.
T1 0-119 Sentence denotes Post-translational modifications distinguish cell surface from Golgi-retained beta 1,4 galactosyltransferase molecules.
T1 0-119 Sentence denotes Post-translational modifications distinguish cell surface from Golgi-retained beta 1,4 galactosyltransferase molecules.
TextSentencer_T2 120-165 Sentence denotes Golgi localization involves active retention.
T2 120-165 Sentence denotes Golgi localization involves active retention.
T2 120-165 Sentence denotes Golgi localization involves active retention.
TextSentencer_T3 166-284 Sentence denotes beta 1,4 Galactosyltransferase (GalT) is a membrane-bound enzyme localized predominantly to the trans-Golgi cisternae.
T3 166-284 Sentence denotes beta 1,4 Galactosyltransferase (GalT) is a membrane-bound enzyme localized predominantly to the trans-Golgi cisternae.
T3 166-284 Sentence denotes beta 1,4 Galactosyltransferase (GalT) is a membrane-bound enzyme localized predominantly to the trans-Golgi cisternae.
TextSentencer_T4 285-459 Sentence denotes Our previous studies have shown that the transmembrane domain of bovine GalT plays a critical role in Golgi localization (Teasdale, R.D., D'Agostaro, G. and Gleeson, P.A., J.
T4 285-459 Sentence denotes Our previous studies have shown that the transmembrane domain of bovine GalT plays a critical role in Golgi localization (Teasdale, R.D., D'Agostaro, G. and Gleeson, P.A., J.
T4 285-495 Sentence denotes Our previous studies have shown that the transmembrane domain of bovine GalT plays a critical role in Golgi localization (Teasdale, R.D., D'Agostaro, G. and Gleeson, P.A., J. Biol. Chem., 267, 4084-4096, 1992).
TextSentencer_T5 460-465 Sentence denotes Biol.
T5 460-465 Sentence denotes Biol.
TextSentencer_T6 466-495 Sentence denotes Chem., 267, 4084-4096, 1992).
T6 466-495 Sentence denotes Chem., 267, 4084-4096, 1992).
TextSentencer_T7 496-717 Sentence denotes Here we have compared the localization and post-translational modifications of full-length bovine GalT with a GalT/hybrid molecule where the transmembrane domain of GalT was replaced with that of the transferrin receptor.
T5 496-717 Sentence denotes Here we have compared the localization and post-translational modifications of full-length bovine GalT with a GalT/hybrid molecule where the transmembrane domain of GalT was replaced with that of the transferrin receptor.
T7 496-717 Sentence denotes Here we have compared the localization and post-translational modifications of full-length bovine GalT with a GalT/hybrid molecule where the transmembrane domain of GalT was replaced with that of the transferrin receptor.
TextSentencer_T8 718-914 Sentence denotes GalT/hybrid molecules were expressed on the surface of transfected cells; however, differences were observed in the distribution of the hybrid molecules between transfected COS and murine L cells.
T6 718-914 Sentence denotes GalT/hybrid molecules were expressed on the surface of transfected cells; however, differences were observed in the distribution of the hybrid molecules between transfected COS and murine L cells.
T8 718-914 Sentence denotes GalT/hybrid molecules were expressed on the surface of transfected cells; however, differences were observed in the distribution of the hybrid molecules between transfected COS and murine L cells.
TextSentencer_T9 915-1218 Sentence denotes In transfected COS cells, the GalT/hybrid protein was expressed efficiently at the cell surface, with little Golgi-localized material, whereas in stable murine L cells, which expressed lower levels of the construct, hybrid molecules were detected both at the cell surface and within the Golgi apparatus.
T7 915-1218 Sentence denotes In transfected COS cells, the GalT/hybrid protein was expressed efficiently at the cell surface, with little Golgi-localized material, whereas in stable murine L cells, which expressed lower levels of the construct, hybrid molecules were detected both at the cell surface and within the Golgi apparatus.
T9 915-1218 Sentence denotes In transfected COS cells, the GalT/hybrid protein was expressed efficiently at the cell surface, with little Golgi-localized material, whereas in stable murine L cells, which expressed lower levels of the construct, hybrid molecules were detected both at the cell surface and within the Golgi apparatus.
TextSentencer_T10 1219-1355 Sentence denotes Expression of the GalT constructs in either COS or L cells produced two glycoprotein products which differed in molecular mass by 7 kDa.
T8 1219-1355 Sentence denotes Expression of the GalT constructs in either COS or L cells produced two glycoprotein products which differed in molecular mass by 7 kDa.
T10 1219-1355 Sentence denotes Expression of the GalT constructs in either COS or L cells produced two glycoprotein products which differed in molecular mass by 7 kDa.
TextSentencer_T11 1356-1549 Sentence denotes The difference in size between the two products is due to post-translational modifications which are inhibited by brefeldin A and are therefore likely to occur in the trans-Golgi network (TGN).
T9 1356-1549 Sentence denotes The difference in size between the two products is due to post-translational modifications which are inhibited by brefeldin A and are therefore likely to occur in the trans-Golgi network (TGN).
T11 1356-1549 Sentence denotes The difference in size between the two products is due to post-translational modifications which are inhibited by brefeldin A and are therefore likely to occur in the trans-Golgi network (TGN).
TextSentencer_T12 1550-1693 Sentence denotes Very little of the high-molecular-weight species was detected for full-length GalT, whereas it was a major product for the GalT/hybrid protein.
T10 1550-1693 Sentence denotes Very little of the high-molecular-weight species was detected for full-length GalT, whereas it was a major product for the GalT/hybrid protein.
T12 1550-1693 Sentence denotes Very little of the high-molecular-weight species was detected for full-length GalT, whereas it was a major product for the GalT/hybrid protein.
TextSentencer_T13 1694-1769 Sentence denotes Only the higher molecular weight species was expressed at the cell surface.
T11 1694-1769 Sentence denotes Only the higher molecular weight species was expressed at the cell surface.
T13 1694-1769 Sentence denotes Only the higher molecular weight species was expressed at the cell surface.
TextSentencer_T14 1770-1970 Sentence denotes Thus, this additional 7 kDa post-translational modification distinguishes molecules retained within the Golgi apparatus (lower M(r) species) from those transported through the TGN to the cell surface.
T12 1770-1970 Sentence denotes Thus, this additional 7 kDa post-translational modification distinguishes molecules retained within the Golgi apparatus (lower M(r) species) from those transported through the TGN to the cell surface.
T14 1770-1970 Sentence denotes Thus, this additional 7 kDa post-translational modification distinguishes molecules retained within the Golgi apparatus (lower M(r) species) from those transported through the TGN to the cell surface.
TextSentencer_T15 1971-2232 Sentence denotes These studies indicate that (i) the level of expression influences the intracellular distribution of GalT/hybrid molecules and (ii) the localization of full-length GalT involves active retention within the Golgi stack, and not retrieval from later compartments.
T13 1971-2232 Sentence denotes These studies indicate that (i) the level of expression influences the intracellular distribution of GalT/hybrid molecules and (ii) the localization of full-length GalT involves active retention within the Golgi stack, and not retrieval from later compartments.
T15 1971-2232 Sentence denotes These studies indicate that (i) the level of expression influences the intracellular distribution of GalT/hybrid molecules and (ii) the localization of full-length GalT involves active retention within the Golgi stack, and not retrieval from later compartments.
TextSentencer_T16 2233-2504 Sentence denotes After treatment of membrane preparations from stable L cell clones with a heterobifunctional cross-linking agent, full-length bovine GalT molecules were found almost exclusively as high-molecular-weight aggregates, suggesting that GalT exists as an oligomer or aggregate.
T14 2233-2504 Sentence denotes After treatment of membrane preparations from stable L cell clones with a heterobifunctional cross-linking agent, full-length bovine GalT molecules were found almost exclusively as high-molecular-weight aggregates, suggesting that GalT exists as an oligomer or aggregate.
T16 2233-2504 Sentence denotes After treatment of membrane preparations from stable L cell clones with a heterobifunctional cross-linking agent, full-length bovine GalT molecules were found almost exclusively as high-molecular-weight aggregates, suggesting that GalT exists as an oligomer or aggregate.
TextSentencer_T17 2505-2574 Sentence denotes This ability to oligomerize may be a requirement for Golgi retention.
T15 2505-2574 Sentence denotes This ability to oligomerize may be a requirement for Golgi retention.
T17 2505-2574 Sentence denotes This ability to oligomerize may be a requirement for Golgi retention.