| Id |
Subject |
Object |
Predicate |
Lexical cue |
| TextSentencer_T1 |
0-106 |
Sentence |
denotes |
Homozygous loss of the interferon genes defines the critical region on 9p that is deleted in lung cancers. |
| T1 |
0-106 |
Sentence |
denotes |
Homozygous loss of the interferon genes defines the critical region on 9p that is deleted in lung cancers. |
| TextSentencer_T2 |
107-283 |
Sentence |
denotes |
Cytogenetic analyses of non-small cell lung cancer have revealed deletions of the short arm of chromosome 9 with breakpoints at 9p11-pter in a significant proportion of tumors. |
| T2 |
107-283 |
Sentence |
denotes |
Cytogenetic analyses of non-small cell lung cancer have revealed deletions of the short arm of chromosome 9 with breakpoints at 9p11-pter in a significant proportion of tumors. |
| TextSentencer_T3 |
284-535 |
Sentence |
denotes |
Recent evidence suggests that homozygous loss of the interferon (IFN) and methylthioadenosine phosphorylase (MTAP) genes located on 9p and a tumor suppressor gene closely linked to them is associated with acute lymphoblastic leukemia and with gliomas. |
| T3 |
284-535 |
Sentence |
denotes |
Recent evidence suggests that homozygous loss of the interferon (IFN) and methylthioadenosine phosphorylase (MTAP) genes located on 9p and a tumor suppressor gene closely linked to them is associated with acute lymphoblastic leukemia and with gliomas. |
| TextSentencer_T4 |
536-696 |
Sentence |
denotes |
We have observed alterations of DNA sequences on 9p which include the IFN genes at a significant frequency in all types of human lung cancers (20 of 56 or 36%). |
| T4 |
536-696 |
Sentence |
denotes |
We have observed alterations of DNA sequences on 9p which include the IFN genes at a significant frequency in all types of human lung cancers (20 of 56 or 36%). |
| TextSentencer_T5 |
697-843 |
Sentence |
denotes |
The genetic alterations observed include homozygous or hemizygous deletions of the IFN genes as well as rearrangement of contiguous DNA sequences. |
| T5 |
697-843 |
Sentence |
denotes |
The genetic alterations observed include homozygous or hemizygous deletions of the IFN genes as well as rearrangement of contiguous DNA sequences. |
| TextSentencer_T6 |
844-949 |
Sentence |
denotes |
In addition to these genomic alterations, 10 of 22 (45%) cell lines examined lacked MTAP enzyme activity. |
| T6 |
844-949 |
Sentence |
denotes |
In addition to these genomic alterations, 10 of 22 (45%) cell lines examined lacked MTAP enzyme activity. |
| TextSentencer_T7 |
950-1093 |
Sentence |
denotes |
Overall, 24 of 56 (43%) lung cancer cell lines examined had hemizygous or homozygous loss of DNA sequences which include the IFN or MTAP genes. |
| T7 |
950-1093 |
Sentence |
denotes |
Overall, 24 of 56 (43%) lung cancer cell lines examined had hemizygous or homozygous loss of DNA sequences which include the IFN or MTAP genes. |
| TextSentencer_T8 |
1094-1264 |
Sentence |
denotes |
These findings suggest that the putative tumor suppressor gene at this locus contributes to the malignant process in lung cancers, as well as other types of human cancer. |
| T8 |
1094-1264 |
Sentence |
denotes |
These findings suggest that the putative tumor suppressor gene at this locus contributes to the malignant process in lung cancers, as well as other types of human cancer. |