| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T1 |
0-78 |
Sentence |
denotes |
Cloning and functional expression of a human eosinophil CC chemokine receptor. |
| T1 |
0-78 |
Sentence |
denotes |
Cloning and functional expression of a human eosinophil CC chemokine receptor. |
| T2 |
79-401 |
Sentence |
denotes |
Eosinophils undergo chemotaxis, degranulate, and exhibit [C2+]i changes in response to the human CC chemokines macrophage inflammatory protein (MIP)-1 alpha, regulated on activation, normal T expressed and secreted (RANTES), and monocyte chemoattractant protein-3 (MCP-3), but the receptors involved have not been defined. |
| T2 |
79-401 |
Sentence |
denotes |
Eosinophils undergo chemotaxis, degranulate, and exhibit [C2+]i changes in response to the human CC chemokines macrophage inflammatory protein (MIP)-1 alpha, regulated on activation, normal T expressed and secreted (RANTES), and monocyte chemoattractant protein-3 (MCP-3), but the receptors involved have not been defined. |
| T3 |
402-537 |
Sentence |
denotes |
We have isolated a human cDNA encoding the first eosinophil-selective chemokine receptor, designated CC chemokine receptor 3 (CC CKR3). |
| T3 |
402-537 |
Sentence |
denotes |
We have isolated a human cDNA encoding the first eosinophil-selective chemokine receptor, designated CC chemokine receptor 3 (CC CKR3). |
| T4 |
538-753 |
Sentence |
denotes |
CC CKR3 is a seven-transmembrane domain G protein-coupled receptor most closely related to the previously reported monocyte- and neutrophil-selective receptor CC CKR1 (also known as the MIP-1 alpha/RANTES receptor). |
| T4 |
538-753 |
Sentence |
denotes |
CC CKR3 is a seven-transmembrane domain G protein-coupled receptor most closely related to the previously reported monocyte- and neutrophil-selective receptor CC CKR1 (also known as the MIP-1 alpha/RANTES receptor). |
| T5 |
754-919 |
Sentence |
denotes |
When [Ca2+]i changes were monitored in stably transfected human embryonic kidney 293 cells, MIP-1 alpha and RANTES were both potent agonists for CC CKR3 and CC CKR1. |
| T5 |
754-919 |
Sentence |
denotes |
When [Ca2+]i changes were monitored in stably transfected human embryonic kidney 293 cells, MIP-1 alpha and RANTES were both potent agonists for CC CKR3 and CC CKR1. |
| T6 |
920-1038 |
Sentence |
denotes |
However, MIP-1 beta was also an agonist for CC CKR3 but not CC CKR1; MCP-3 was an agonist for CC CKR1 but not CC CKR3. |
| T6 |
920-1038 |
Sentence |
denotes |
However, MIP-1 beta was also an agonist for CC CKR3 but not CC CKR1; MCP-3 was an agonist for CC CKR1 but not CC CKR3. |
| T7 |
1039-1156 |
Sentence |
denotes |
CC CKR3 may be one of the host factors responsible for selective recruitment of eosinophils to sites of inflammation. |
| T7 |
1039-1156 |
Sentence |
denotes |
CC CKR3 may be one of the host factors responsible for selective recruitment of eosinophils to sites of inflammation. |