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PubMed:7592883 JSONTXT 25 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
T1 0-103 Sentence denotes The mitogenic effects of the B beta chain of fibrinogen are mediated through cell surface calreticulin.
T1 0-103 Sentence denotes The mitogenic effects of the B beta chain of fibrinogen are mediated through cell surface calreticulin.
T2 104-339 Sentence denotes We have previously shown that soluble partially degraded fibrin(ogen) remains in solution after fibrin clot formation and is a potent fibroblast mitogen (Gray, A.J., Bishop, J.E., Reeves J.T., Mecham, R.P., and Laurent, G.J. (1995) Am.
T2 104-339 Sentence denotes We have previously shown that soluble partially degraded fibrin(ogen) remains in solution after fibrin clot formation and is a potent fibroblast mitogen (Gray, A.J., Bishop, J.E., Reeves J.T., Mecham, R.P., and Laurent, G.J. (1995) Am.
T3 340-342 Sentence denotes J.
T3 340-342 Sentence denotes J.
T4 343-352 Sentence denotes Cell Mol.
T4 343-352 Sentence denotes Cell Mol.
T5 353-358 Sentence denotes Biol.
T5 353-358 Sentence denotes Biol.
T6 359-372 Sentence denotes 12, 684-690).
T6 359-372 Sentence denotes 12, 684-690).
T7 373-505 Sentence denotes Mitogenic sites within the fibrin(ogen) molecule are located on the A alpha and B beta chains of the protein (Gray, A.J., Bishop, J.
T7 373-505 Sentence denotes Mitogenic sites within the fibrin(ogen) molecule are located on the A alpha and B beta chains of the protein (Gray, A.J., Bishop, J.
T8 506-551 Sentence denotes E., Reeves, J.T., and Laurent, G.J. (1993) J.
T8 506-551 Sentence denotes E., Reeves, J.T., and Laurent, G.J. (1993) J.
T9 552-561 Sentence denotes Cell Sci.
T9 552-561 Sentence denotes Cell Sci.
T10 562-576 Sentence denotes 104, 409-413).
T10 562-576 Sentence denotes 104, 409-413).
T11 577-661 Sentence denotes However, receptor pathways through which mitogenic effects are mediated are unknown.
T11 577-661 Sentence denotes However, receptor pathways through which mitogenic effects are mediated are unknown.
T12 662-816 Sentence denotes The present study sought to determine the nature of fibrin(ogen) receptors expressed on human fibroblasts which interact with the fibrinogen B beta chain.
T12 662-816 Sentence denotes The present study sought to determine the nature of fibrin(ogen) receptors expressed on human fibroblasts which interact with the fibrinogen B beta chain.
T13 817-946 Sentence denotes Receptor complexes were isolated from 125I-surface-labeled fibroblasts and purified on a fibrinogen B beta chain affinity column.
T13 817-946 Sentence denotes Receptor complexes were isolated from 125I-surface-labeled fibroblasts and purified on a fibrinogen B beta chain affinity column.
T14 947-1130 Sentence denotes Subsequent high performance liquid chromatography and SDS-polyacrylamide gel electrophoresis analysis indicated fibrinogen B beta chain bound specifically to a 60-kDa surface protein.
T14 947-1130 Sentence denotes Subsequent high performance liquid chromatography and SDS-polyacrylamide gel electrophoresis analysis indicated fibrinogen B beta chain bound specifically to a 60-kDa surface protein.
T15 1131-1233 Sentence denotes Sequence analysis of the amino terminus of this protein indicated 100% homology to human calreticulin.
T15 1131-1233 Sentence denotes Sequence analysis of the amino terminus of this protein indicated 100% homology to human calreticulin.
T16 1234-1406 Sentence denotes Immunoprecipitation experiments employing a polyclonal anti-calreticulin antibody provided further evidence that the 60-kDa protein isolated in this study was calreticulin.
T16 1234-1406 Sentence denotes Immunoprecipitation experiments employing a polyclonal anti-calreticulin antibody provided further evidence that the 60-kDa protein isolated in this study was calreticulin.
T17 1407-1555 Sentence denotes Further, polyclonal antibodies to human calreticulin significantly inhibited the mitogenic activity of fibrinogen B beta chain on human fibroblasts.
T17 1407-1555 Sentence denotes Further, polyclonal antibodies to human calreticulin significantly inhibited the mitogenic activity of fibrinogen B beta chain on human fibroblasts.
T18 1556-1688 Sentence denotes The present study has shown that cell surface calreticulin binds to the B beta chain of fibrinogen mediating its mitogenic activity.
T18 1556-1688 Sentence denotes The present study has shown that cell surface calreticulin binds to the B beta chain of fibrinogen mediating its mitogenic activity.