| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T1 |
0-84 |
Sentence |
denotes |
Use of monoclonal antibodies as probes of simian virus 40 T antigen ATPase activity. |
| T1 |
0-84 |
Sentence |
denotes |
Use of monoclonal antibodies as probes of simian virus 40 T antigen ATPase activity. |
| T2 |
85-240 |
Sentence |
denotes |
We have investigated the ATPase activity of simian virus 40 (SV40) large T antigen by using monoclonal antibodies as specific probes of enzymatic activity. |
| T2 |
85-240 |
Sentence |
denotes |
We have investigated the ATPase activity of simian virus 40 (SV40) large T antigen by using monoclonal antibodies as specific probes of enzymatic activity. |
| T3 |
241-400 |
Sentence |
denotes |
Three hybridoma cell lines secreting anti-T antigen antibodies were derived from mice that were immunized with D2 T antigen, an SV40 T antigen-related protein. |
| T3 |
241-400 |
Sentence |
denotes |
Three hybridoma cell lines secreting anti-T antigen antibodies were derived from mice that were immunized with D2 T antigen, an SV40 T antigen-related protein. |
| T4 |
401-498 |
Sentence |
denotes |
Monoclonal antibodies secreted by these hybridomas bind to three distinct T-antigen determinants. |
| T4 |
401-498 |
Sentence |
denotes |
Monoclonal antibodies secreted by these hybridomas bind to three distinct T-antigen determinants. |
| T5 |
499-645 |
Sentence |
denotes |
In order to bind to T antigen, the three antibodies required amino acid residues coded by the region of the A gene between 0.37 and 0.29 map unit. |
| T5 |
499-645 |
Sentence |
denotes |
In order to bind to T antigen, the three antibodies required amino acid residues coded by the region of the A gene between 0.37 and 0.29 map unit. |
| T6 |
646-733 |
Sentence |
denotes |
Two of these antibodies (DL3C3 and DL3C4) strongly inhibited T antigen ATPase activity. |
| T6 |
646-733 |
Sentence |
denotes |
Two of these antibodies (DL3C3 and DL3C4) strongly inhibited T antigen ATPase activity. |
| T7 |
734-860 |
Sentence |
denotes |
The third antibody (DL3C5) only weakly inhibited the ATPase activity possibly by decreasing the affinity of T antigen for ATP. |
| T7 |
734-860 |
Sentence |
denotes |
The third antibody (DL3C5) only weakly inhibited the ATPase activity possibly by decreasing the affinity of T antigen for ATP. |
| T8 |
861-1043 |
Sentence |
denotes |
These results demonstrate that the ATPase activity is intrinsic to T antigen and suggest that the ATPase function of T antigen maps on the SV40 A gene between 0.37 and 0.29 map unit. |
| T8 |
861-1043 |
Sentence |
denotes |
These results demonstrate that the ATPase activity is intrinsic to T antigen and suggest that the ATPase function of T antigen maps on the SV40 A gene between 0.37 and 0.29 map unit. |
| T9 |
1044-1234 |
Sentence |
denotes |
A T antigen-specific ATPase assay capable of detecting low levels of T antigen in crude extracts of SV40 infected cells was developed by using 3C5 to immobilize an active form of the enzyme. |
| T9 |
1044-1234 |
Sentence |
denotes |
A T antigen-specific ATPase assay capable of detecting low levels of T antigen in crude extracts of SV40 infected cells was developed by using 3C5 to immobilize an active form of the enzyme. |
| T10 |
1235-1340 |
Sentence |
denotes |
These results indicate that monoclonal antibodies can be used as probes of enzyme structure and function. |
| T10 |
1235-1340 |
Sentence |
denotes |
These results indicate that monoclonal antibodies can be used as probes of enzyme structure and function. |