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PubMed:6159357 JSONTXT 22 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
T1 0-148 Sentence denotes Effects of hydrogen peroxide on basal and hormone-stimulated lipolysis in perifused rat fat cells in relation to the mechanism of action of insulin.
T1 0-148 Sentence denotes Effects of hydrogen peroxide on basal and hormone-stimulated lipolysis in perifused rat fat cells in relation to the mechanism of action of insulin.
T2 149-392 Sentence denotes Since insulin is known to stimulate intracellular hydrogen peroxide production in rat epididymal fat cells, the effects of exogenous hydrogen peroxide on rates of basal and hormone-stimulated lipolysis were investigated in a perifusion system.
T2 149-392 Sentence denotes Since insulin is known to stimulate intracellular hydrogen peroxide production in rat epididymal fat cells, the effects of exogenous hydrogen peroxide on rates of basal and hormone-stimulated lipolysis were investigated in a perifusion system.
T3 393-544 Sentence denotes H2O2 (60 microM) caused a weak and transient stimulation of basal lipolysis that did not interfere with subsequent activation of lipolysis by hormones.
T3 393-544 Sentence denotes H2O2 (60 microM) caused a weak and transient stimulation of basal lipolysis that did not interfere with subsequent activation of lipolysis by hormones.
T4 545-754 Sentence denotes More importantly, lipolysis stimulated submaximally with ritodrine (10(-7) M) or glucagon (10(-9) M) was inhibited by H2O2 in a manner similar to insulin, although slight differences in time course were noted.
T4 545-754 Sentence denotes More importantly, lipolysis stimulated submaximally with ritodrine (10(-7) M) or glucagon (10(-9) M) was inhibited by H2O2 in a manner similar to insulin, although slight differences in time course were noted.
T5 755-844 Sentence denotes Ritodrine served as a beta-adrenergic agonist resistant to oxidative destruction by H2O2.
T5 755-844 Sentence denotes Ritodrine served as a beta-adrenergic agonist resistant to oxidative destruction by H2O2.
T6 845-927 Sentence denotes The inhibition of lipolysis was reversible upon cessation of perifusion with H2O2.
T6 845-927 Sentence denotes The inhibition of lipolysis was reversible upon cessation of perifusion with H2O2.
T7 928-1057 Sentence denotes These findings ruled out oxidative destruction of the hormone or cell death as explanations for the antilipolytic effect of H2O2.
T7 928-1057 Sentence denotes These findings ruled out oxidative destruction of the hormone or cell death as explanations for the antilipolytic effect of H2O2.
T8 1058-1267 Sentence denotes Like insulin, H2O2 also inhibited 1-methyl-3-isobutylxanthine (4 X 10(-6) M)-stimulated lipolysis, but whereas insulin inhibited lipolysis stimulated by dibutyryl-cAMP (4 X 10(-4) M), H2O2 further enhanced it.
T8 1058-1267 Sentence denotes Like insulin, H2O2 also inhibited 1-methyl-3-isobutylxanthine (4 X 10(-6) M)-stimulated lipolysis, but whereas insulin inhibited lipolysis stimulated by dibutyryl-cAMP (4 X 10(-4) M), H2O2 further enhanced it.
T9 1268-1477 Sentence denotes These findings add another case to the growing list of insulin effects on adipocytes that can be mimicked by exogenous H2O2, and they hint at a site where the mechanisms of action of the two agents may differ.
T9 1268-1477 Sentence denotes These findings add another case to the growing list of insulin effects on adipocytes that can be mimicked by exogenous H2O2, and they hint at a site where the mechanisms of action of the two agents may differ.