| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T1 |
0-68 |
Sentence |
denotes |
Characterization of lactose carrier mutants which transport maltose. |
| T2 |
69-100 |
Sentence |
denotes |
Brooker and Wilson (Brooker, R. |
| T3 |
101-119 |
Sentence |
denotes |
J., and Wilson, T. |
| T4 |
120-135 |
Sentence |
denotes |
H. (1985) Proc. |
| T5 |
136-141 |
Sentence |
denotes |
Natl. |
| T6 |
142-147 |
Sentence |
denotes |
Acad. |
| T7 |
148-152 |
Sentence |
denotes |
Sci. |
| T8 |
153-155 |
Sentence |
denotes |
U. |
| T9 |
156-158 |
Sentence |
denotes |
S. |
| T10 |
159-161 |
Sentence |
denotes |
A. |
| T11 |
162-258 |
Sentence |
denotes |
82, 3959-3963) previously isolated lactose carrier mutants which were able to transport maltose. |
| T12 |
259-363 |
Sentence |
denotes |
All of the mutants were found to be single amino acid substitutions for alanine 177 or for tyrosine 236. |
| T13 |
364-547 |
Sentence |
denotes |
In the present study, we have examined the ability of these mutants to transport maltose, lactose, o-nitrophenyl-beta-D-galactopyranoside, methyl-beta-D-thiogalactopyranoside, and H+. |
| T14 |
548-733 |
Sentence |
denotes |
Both the position 177 and 236 mutants have enhanced rates of maltose transport and exhibit apparent Km values for maltose which are substantially less than that of the wild-type strain. |
| T15 |
734-948 |
Sentence |
denotes |
The position 177 mutants transport lactose and other galactosides at a normal rate and with normal affinity during downhill transport and show counterflow transport rates which are faster than the wild-type strain. |
| T16 |
949-1111 |
Sentence |
denotes |
Interestingly, these mutants are markedly defective in accumulating substrates against a concentration gradient, yet retain a normal H+:galactoside stoichiometry. |
| T17 |
1112-1277 |
Sentence |
denotes |
The position 236 mutants appear to be defective in the downhill, uphill, and counterflow transport of galactosides but exhibit a normal H+:galactoside stoichiometry. |
