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PubMed:3567993 JSONTXT 23 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-130 Sentence denotes The conformation of glycans of the oligo-D-mannosidic type, and their interaction with concanavalin A: a computer-modelling study.
T1 0-130 Sentence denotes The conformation of glycans of the oligo-D-mannosidic type, and their interaction with concanavalin A: a computer-modelling study.
TextSentencer_T2 131-259 Sentence denotes The favored conformations of glycans of the oligo-D-mannosidic type have been determined by using empirical energy calculations.
T2 131-259 Sentence denotes The favored conformations of glycans of the oligo-D-mannosidic type have been determined by using empirical energy calculations.
TextSentencer_T3 260-505 Sentence denotes An interesting aspect is that the alpha-(1----3)-linked terminal D-mannose residue of the outer trimannosidic core fragment, in all the conformations which fall within 5 kcal.mol-1 of the global minimum, always lies close to the chitobiose core.
T3 260-505 Sentence denotes An interesting aspect is that the alpha-(1----3)-linked terminal D-mannose residue of the outer trimannosidic core fragment, in all the conformations which fall within 5 kcal.mol-1 of the global minimum, always lies close to the chitobiose core.
TextSentencer_T4 506-575 Sentence denotes These models are in general agreement with the available n.m.r. data.
T4 506-575 Sentence denotes These models are in general agreement with the available n.m.r. data.
TextSentencer_T5 576-855 Sentence denotes The probable modes of binding of these glycans to concanavalin A (Con A) were determined, by using a computer-modelling technique which identifies the positions for the different conformers of the carbohydrate in the binding site of Con A, based on stereochemical considerations.
T5 576-855 Sentence denotes The probable modes of binding of these glycans to concanavalin A (Con A) were determined, by using a computer-modelling technique which identifies the positions for the different conformers of the carbohydrate in the binding site of Con A, based on stereochemical considerations.
TextSentencer_T6 856-1079 Sentence denotes These studies showed that Con A can bind only to two of the three terminal D-mannose residues in these glycans, because the D-mannose residue which lies close to the chitobiose core is inaccessible for the binding of Con A.
T6 856-1079 Sentence denotes These studies showed that Con A can bind only to two of the three terminal D-mannose residues in these glycans, because the D-mannose residue which lies close to the chitobiose core is inaccessible for the binding of Con A.
TextSentencer_T7 1080-1185 Sentence denotes Of these two terminal D-mannose residues, the alpha-(1----6)-linked D-mannose may bind the more strongly.
T7 1080-1185 Sentence denotes Of these two terminal D-mannose residues, the alpha-(1----6)-linked D-mannose may bind the more strongly.
TextSentencer_T8 1186-1327 Sentence denotes Furthermore, it is shown that the internal D-mannose residue will, at best, interact very weakly with the carbohydrate-binding site of Con A.
T8 1186-1327 Sentence denotes Furthermore, it is shown that the internal D-mannose residue will, at best, interact very weakly with the carbohydrate-binding site of Con A.
TextSentencer_T9 1328-1428 Sentence denotes These results rationalize well the available data on the binding affinity of these glycans to Con A.
T9 1328-1428 Sentence denotes These results rationalize well the available data on the binding affinity of these glycans to Con A.
TextSentencer_T10 1429-1690 Sentence denotes They further support the conclusion that the binding affinity of a glycan to Con A does not depend on the number in the glycan, of D-mannose residues which possess free 3-, 4-, and 6-hydroxyl groups, but, rather, on the accessibility of these residues to Con A.
T10 1429-1690 Sentence denotes They further support the conclusion that the binding affinity of a glycan to Con A does not depend on the number in the glycan, of D-mannose residues which possess free 3-, 4-, and 6-hydroxyl groups, but, rather, on the accessibility of these residues to Con A.