| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T1 |
0-96 |
Sentence |
denotes |
Sulfated proteoglycans and sulfated proteins in guinea pig megakaryocytes and platelets in vivo. |
| T1 |
0-96 |
Sentence |
denotes |
Sulfated proteoglycans and sulfated proteins in guinea pig megakaryocytes and platelets in vivo. |
| T2 |
97-159 |
Sentence |
denotes |
Relevance to megakaryocyte maturation and platelet activation. |
| T2 |
97-159 |
Sentence |
denotes |
Relevance to megakaryocyte maturation and platelet activation. |
| T3 |
160-258 |
Sentence |
denotes |
This study has examined changes in proteoglycan synthesis during megakaryocyte maturation in vivo. |
| T3 |
160-258 |
Sentence |
denotes |
This study has examined changes in proteoglycan synthesis during megakaryocyte maturation in vivo. |
| T4 |
259-372 |
Sentence |
denotes |
Guinea pigs were injected with Na235SO4, and megakaryocytes and platelets were isolated from 3 h to 5 days later. |
| T4 |
259-372 |
Sentence |
denotes |
Guinea pigs were injected with Na235SO4, and megakaryocytes and platelets were isolated from 3 h to 5 days later. |
| T5 |
373-579 |
Sentence |
denotes |
The proteoglycans and other sulfated molecules in both cells were characterized at each time point by gel filtration, ion-exchange chromatography, gel electrophoresis, and chemical and enzymatic digestions. |
| T5 |
373-579 |
Sentence |
denotes |
The proteoglycans and other sulfated molecules in both cells were characterized at each time point by gel filtration, ion-exchange chromatography, gel electrophoresis, and chemical and enzymatic digestions. |
| T6 |
580-678 |
Sentence |
denotes |
Two populations of chondroitin 6-sulfate proteoglycans were found by DEAE-Sephacel chromatography. |
| T6 |
580-678 |
Sentence |
denotes |
Two populations of chondroitin 6-sulfate proteoglycans were found by DEAE-Sephacel chromatography. |
| T7 |
679-805 |
Sentence |
denotes |
The major fraction was eluted with 4 M guanidine hydrochloride and the minor fraction with 4 M guanidine HCl, 2% Triton X-100. |
| T7 |
679-805 |
Sentence |
denotes |
The major fraction was eluted with 4 M guanidine hydrochloride and the minor fraction with 4 M guanidine HCl, 2% Triton X-100. |
| T8 |
806-1016 |
Sentence |
denotes |
The Kav of the major proteoglycan peak in the platelets at 1 day after injection was 0.18-0.20 on Sepharose CL-6B and decreased gradually to 0.12 by 3 days, when proteoglycan radioactivity per cell was maximal. |
| T8 |
806-1016 |
Sentence |
denotes |
The Kav of the major proteoglycan peak in the platelets at 1 day after injection was 0.18-0.20 on Sepharose CL-6B and decreased gradually to 0.12 by 3 days, when proteoglycan radioactivity per cell was maximal. |
| T9 |
1017-1095 |
Sentence |
denotes |
The peak for megakaryocyte proteoglycans at 3 h was broad, with Kav = 0.1-0.2. |
| T9 |
1017-1095 |
Sentence |
denotes |
The peak for megakaryocyte proteoglycans at 3 h was broad, with Kav = 0.1-0.2. |
| T10 |
1096-1226 |
Sentence |
denotes |
The appearance of different portions of the proteoglycan peak in platelets coincided with their disappearance from megakaryocytes. |
| T10 |
1096-1226 |
Sentence |
denotes |
The appearance of different portions of the proteoglycan peak in platelets coincided with their disappearance from megakaryocytes. |
| T11 |
1227-1294 |
Sentence |
denotes |
Proteoglycan size was a function of glycosaminoglycan chain length. |
| T11 |
1227-1294 |
Sentence |
denotes |
Proteoglycan size was a function of glycosaminoglycan chain length. |
| T12 |
1295-1453 |
Sentence |
denotes |
The proteoglycans eluted with Triton X-100 from DEAE-Sephacel (Kav = 0.04-0.07 on Sepharose CL-6B) were not labeled in platelets until 2 days after injection. |
| T12 |
1295-1453 |
Sentence |
denotes |
The proteoglycans eluted with Triton X-100 from DEAE-Sephacel (Kav = 0.04-0.07 on Sepharose CL-6B) were not labeled in platelets until 2 days after injection. |
| T13 |
1454-1587 |
Sentence |
denotes |
Our data suggest that megakaryocytes synthesize different-sized chondroitin sulfate proteoglycans at different stages of development. |
| T13 |
1454-1587 |
Sentence |
denotes |
Our data suggest that megakaryocytes synthesize different-sized chondroitin sulfate proteoglycans at different stages of development. |
| T14 |
1588-1721 |
Sentence |
denotes |
The proteoglycans of the major fraction were released from platelets in response to thrombin, and a small amount was released by ADP. |
| T14 |
1588-1721 |
Sentence |
denotes |
The proteoglycans of the major fraction were released from platelets in response to thrombin, and a small amount was released by ADP. |
| T15 |
1722-1804 |
Sentence |
denotes |
The proteoglycans of the Triton X-100 eluate were not released by thrombin or ADP. |
| T15 |
1722-1804 |
Sentence |
denotes |
The proteoglycans of the Triton X-100 eluate were not released by thrombin or ADP. |
| T16 |
1805-1953 |
Sentence |
denotes |
About 20% of the sulfate radioactivity was incorporated into molecules that appear to be sulfated proteins and were not released by thrombin or ADP. |
| T16 |
1805-1953 |
Sentence |
denotes |
About 20% of the sulfate radioactivity was incorporated into molecules that appear to be sulfated proteins and were not released by thrombin or ADP. |