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PubMed:33174592 JSONTXT 37 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
T1 0-85 Sentence denotes Composition of the immunoglobulin G glycome associates with the severity of COVID-19.
T1 0-85 Sentence denotes Composition of the immunoglobulin G glycome associates with the severity of COVID-19.
T2 86-195 Sentence denotes A large variation in the severity of disease symptoms is one of the key open questions in COVID-19 pandemics.
T2 86-195 Sentence denotes A large variation in the severity of disease symptoms is one of the key open questions in COVID-19 pandemics.
T3 196-427 Sentence denotes The fact that only a small subset of people infected with SARS-CoV-2 develop severe disease suggests that there have to be some predisposing factors, but biomarkers that reliably predict disease severity have not been found so far.
T3 196-427 Sentence denotes The fact that only a small subset of people infected with SARS-CoV-2 develop severe disease suggests that there have to be some predisposing factors, but biomarkers that reliably predict disease severity have not been found so far.
T4 428-730 Sentence denotes Since overactivation of the immune system is implicated in a severe form of COVID-19 and the IgG glycosylation is known to be involved in the regulation of different immune processes, we evaluated the association of inter-individual variation in IgG N-glycome composition with the severity of COVID-19.
T4 428-730 Sentence denotes Since overactivation of the immune system is implicated in a severe form of COVID-19 and the IgG glycosylation is known to be involved in the regulation of different immune processes, we evaluated the association of inter-individual variation in IgG N-glycome composition with the severity of COVID-19.
T5 731-908 Sentence denotes The analysis of 166 severe and 167 mild cases from hospitals in Spain, Italy and Portugal revealed statistically significant differences in the composition of the IgG N-glycome.
T5 731-908 Sentence denotes The analysis of 166 severe and 167 mild cases from hospitals in Spain, Italy and Portugal revealed statistically significant differences in the composition of the IgG N-glycome.
T6 909-1038 Sentence denotes The most notable difference was the decrease in bisecting N-acetylglucosamine (GlcNAc) in severe patients from all three cohorts.
T6 909-1038 Sentence denotes The most notable difference was the decrease in bisecting N-acetylglucosamine (GlcNAc) in severe patients from all three cohorts.
T7 1039-1216 Sentence denotes IgG galactosylation was also lower in severe cases in all cohorts, but the difference in galactosylation was not statistically significant after correction for multiple testing.
T7 1039-1216 Sentence denotes IgG galactosylation was also lower in severe cases in all cohorts, but the difference in galactosylation was not statistically significant after correction for multiple testing.