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PubMed:3180550 JSONTXT 11 Projects

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Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-46 Sentence denotes Alkaptonuria and ochronosis in three siblings.
T1 0-46 Sentence denotes Alkaptonuria and ochronosis in three siblings.
TextSentencer_T2 47-106 Sentence denotes Ascorbic acid treatment monitored by urinary HGA excretion.
T2 47-106 Sentence denotes Ascorbic acid treatment monitored by urinary HGA excretion.
TextSentencer_T3 107-342 Sentence denotes Patients with alkaptonuria lack homogentisate 1,2-dioxygenase leading to retention of homogentistic acid (HGA) in body fluids and eventually to tissue deposition of oxidation products, giving rise to the clinical picture of ochronosis.
T3 107-342 Sentence denotes Patients with alkaptonuria lack homogentisate 1,2-dioxygenase leading to retention of homogentistic acid (HGA) in body fluids and eventually to tissue deposition of oxidation products, giving rise to the clinical picture of ochronosis.
TextSentencer_T4 343-557 Sentence denotes Ascorbic acid is a known inhibitor of the enzyme which catalyses the oxidation of homogentisic acid (HGA) to the polymer with affinity for collagen and was used in the treatment of three siblings with alkaptonuria.
T4 343-557 Sentence denotes Ascorbic acid is a known inhibitor of the enzyme which catalyses the oxidation of homogentisic acid (HGA) to the polymer with affinity for collagen and was used in the treatment of three siblings with alkaptonuria.
TextSentencer_T5 558-614 Sentence denotes Ascorbic acid 500 mg bid was administered for 12 months.
T5 558-614 Sentence denotes Ascorbic acid 500 mg bid was administered for 12 months.
TextSentencer_T6 615-729 Sentence denotes Two of the siblings tolerated the treatment, and in one the symptoms improved, whereas in the other they worsened.
T6 615-729 Sentence denotes Two of the siblings tolerated the treatment, and in one the symptoms improved, whereas in the other they worsened.
TextSentencer_T7 730-801 Sentence denotes Plasma and urinary levels of HGA were monitored with a new HPLC method.
T7 730-801 Sentence denotes Plasma and urinary levels of HGA were monitored with a new HPLC method.
TextSentencer_T8 802-876 Sentence denotes Ascorbic acid is not effective in the treatment of symptomatic ochronosis.
T8 802-876 Sentence denotes Ascorbic acid is not effective in the treatment of symptomatic ochronosis.