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PubMed:31337705 JSONTXT 39 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
T1 0-113 Sentence denotes Sulfated Lewis A trisaccharide on oviduct membrane glycoproteins binds bovine sperm and lengthens sperm lifespan.
T1 0-113 Sentence denotes Sulfated Lewis A trisaccharide on oviduct membrane glycoproteins binds bovine sperm and lengthens sperm lifespan.
T2 114-253 Sentence denotes A fraction of sperm deposited at mating or insemination reaches the oviduct isthmus, where sperm are retained and thereby form a reservoir.
T2 114-253 Sentence denotes A fraction of sperm deposited at mating or insemination reaches the oviduct isthmus, where sperm are retained and thereby form a reservoir.
T3 254-390 Sentence denotes This reservoir delays capacitation, prevents polyspermy, selects a fertile population of sperm, and, foremost, increases sperm lifespan.
T3 254-390 Sentence denotes This reservoir delays capacitation, prevents polyspermy, selects a fertile population of sperm, and, foremost, increases sperm lifespan.
T4 391-496 Sentence denotes The molecular interactions underlying the formation of a sperm reservoir are becoming clearer in mammals.
T4 391-496 Sentence denotes The molecular interactions underlying the formation of a sperm reservoir are becoming clearer in mammals.
T5 497-559 Sentence denotes Sperm lectins bind to oviductal glycans to form the reservoir.
T5 497-559 Sentence denotes Sperm lectins bind to oviductal glycans to form the reservoir.
T6 560-808 Sentence denotes Herein, we found that the highest percentage of bovine sperm bound to the 3'-O-sulfated form of Lewis A (suLeA) trisaccharide and sialylated Lewis A and that fluoresceinated versions of each localized to receptors on the anterior head of the sperm.
T6 560-808 Sentence denotes Herein, we found that the highest percentage of bovine sperm bound to the 3'-O-sulfated form of Lewis A (suLeA) trisaccharide and sialylated Lewis A and that fluoresceinated versions of each localized to receptors on the anterior head of the sperm.
T7 809-936 Sentence denotes Following capacitation, binding to suLeA decreased significantly, a potential explanation for sperm release from the reservoir.
T7 809-936 Sentence denotes Following capacitation, binding to suLeA decreased significantly, a potential explanation for sperm release from the reservoir.
T8 937-1118 Sentence denotes MS and immunohistochemistry analyses indicated that suLeA motifs were present predominantly on O-linked glycans initiated by GalNAc residues, but no sialylated Lewis A was detected.
T8 937-1118 Sentence denotes MS and immunohistochemistry analyses indicated that suLeA motifs were present predominantly on O-linked glycans initiated by GalNAc residues, but no sialylated Lewis A was detected.
T9 1119-1311 Sentence denotes To determine whether sperm binding to isolated suLeA in vitro could mimic in vivo sperm binding to oviduct cells and increase sperm longevity, we immobilized suLeA and incubated it with sperm.
T9 1119-1311 Sentence denotes To determine whether sperm binding to isolated suLeA in vitro could mimic in vivo sperm binding to oviduct cells and increase sperm longevity, we immobilized suLeA and incubated it with sperm.
T10 1312-1652 Sentence denotes Using free-swimming sperm and sperm bound to immobilized laminin as controls, we observed that over 96 h, the viability of free-swimming sperm decreased to 10%, and that of sperm bound to immobilized laminin decreased to about 50%, whereas viability of sperm bound to immobilized suLeA was highest throughout the incubation and 60% at 96 h.
T10 1312-1652 Sentence denotes Using free-swimming sperm and sperm bound to immobilized laminin as controls, we observed that over 96 h, the viability of free-swimming sperm decreased to 10%, and that of sperm bound to immobilized laminin decreased to about 50%, whereas viability of sperm bound to immobilized suLeA was highest throughout the incubation and 60% at 96 h.
T11 1653-1784 Sentence denotes These results indicate that bovine sperm binding to oviduct suLeA retains sperm for reservoir formation and extends sperm lifespan.
T11 1653-1784 Sentence denotes These results indicate that bovine sperm binding to oviduct suLeA retains sperm for reservoir formation and extends sperm lifespan.