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PubMed:3108247 JSONTXT 29 Projects

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Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-147 Sentence denotes Lethal perinatal osteogenesis imperfecta due to the substitution of arginine for glycine at residue 391 of the alpha 1(I) chain of type I collagen.
T1 0-147 Sentence denotes Lethal perinatal osteogenesis imperfecta due to the substitution of arginine for glycine at residue 391 of the alpha 1(I) chain of type I collagen.
TextSentencer_T2 148-297 Sentence denotes A baby with the lethal perinatal form of osteogenesis imperfecta was shown to have a structural defect in the alpha 1(I) chain of type I procollagen.
T2 148-297 Sentence denotes A baby with the lethal perinatal form of osteogenesis imperfecta was shown to have a structural defect in the alpha 1(I) chain of type I procollagen.
TextSentencer_T3 298-430 Sentence denotes Normal and mutant alpha 1(I) CB8 cyanogen bromide peptides, from the helical part of the alpha 1(I) chains, were purified from bone.
T3 298-430 Sentence denotes Normal and mutant alpha 1(I) CB8 cyanogen bromide peptides, from the helical part of the alpha 1(I) chains, were purified from bone.
TextSentencer_T4 431-633 Sentence denotes Amino acid sequencing of tryptic peptides derived from the mutant alpha 1(I) CB8 peptide showed that the glycine residue at position 391 of the alpha 1(I) chain had been replaced by an arginine residue.
T4 431-633 Sentence denotes Amino acid sequencing of tryptic peptides derived from the mutant alpha 1(I) CB8 peptide showed that the glycine residue at position 391 of the alpha 1(I) chain had been replaced by an arginine residue.
TextSentencer_T5 634-814 Sentence denotes This substitution accounted for the more basic charged form of this peptide that was observed on two-dimensional electrophoresis of the collagen peptides obtained from the tissues.
T5 634-814 Sentence denotes This substitution accounted for the more basic charged form of this peptide that was observed on two-dimensional electrophoresis of the collagen peptides obtained from the tissues.
TextSentencer_T6 815-1012 Sentence denotes The substitution was associated with increased enzymatic hydroxylation of lysine residues in the alpha 1(I) CB8 and the adjoining CB3 peptides but not in the carboxyl-terminal CB6 and CB7 peptides.
T6 815-1012 Sentence denotes The substitution was associated with increased enzymatic hydroxylation of lysine residues in the alpha 1(I) CB8 and the adjoining CB3 peptides but not in the carboxyl-terminal CB6 and CB7 peptides.
TextSentencer_T7 1013-1147 Sentence denotes This finding suggested that the sequence abnormality had interfered with the propagation of the triple helix across the mutant region.
T7 1013-1147 Sentence denotes This finding suggested that the sequence abnormality had interfered with the propagation of the triple helix across the mutant region.
TextSentencer_T8 1148-1241 Sentence denotes The abnormal collagen was not incorporated into the more insoluble fraction of bone collagen.
T8 1148-1241 Sentence denotes The abnormal collagen was not incorporated into the more insoluble fraction of bone collagen.
TextSentencer_T9 1242-1454 Sentence denotes The baby appeared to be heterozygous for the sequence abnormality and as the parents did not show any evidence of the defect it is likely that the baby had a new mutation of one allele of the pro-alpha 1(I) gene.
T9 1242-1454 Sentence denotes The baby appeared to be heterozygous for the sequence abnormality and as the parents did not show any evidence of the defect it is likely that the baby had a new mutation of one allele of the pro-alpha 1(I) gene.
TextSentencer_T10 1455-1593 Sentence denotes The amino acid substitution could result from a single nucleotide mutation in the codon GGC (glycine) to produce the codon CGC (arginine).
T10 1455-1593 Sentence denotes The amino acid substitution could result from a single nucleotide mutation in the codon GGC (glycine) to produce the codon CGC (arginine).