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PubMed:31059263 JSONTXT 40 Projects

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Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-114 Sentence denotes Specific Proteomes of Hippocampal Regions CA2 and CA1 Reveal Proteins Linked to the Unique Physiology of Area CA2.
T1 0-114 Sentence denotes Specific Proteomes of Hippocampal Regions CA2 and CA1 Reveal Proteins Linked to the Unique Physiology of Area CA2.
TextSentencer_T2 115-204 Sentence denotes The hippocampus is well established as an essential brain center for learning and memory.
T2 115-204 Sentence denotes The hippocampus is well established as an essential brain center for learning and memory.
TextSentencer_T3 205-370 Sentence denotes Within the hippocampus, recent studies show that area CA2 is important for social memory and is an anomaly compared to its better-understood neighboring region, CA1.
T3 205-370 Sentence denotes Within the hippocampus, recent studies show that area CA2 is important for social memory and is an anomaly compared to its better-understood neighboring region, CA1.
TextSentencer_T4 371-523 Sentence denotes Unlike CA1, CA2 displays a lack of typical synaptic plasticity, enhanced calcium buffering and extrusion, and resilience to cell death following injury.
T4 371-523 Sentence denotes Unlike CA1, CA2 displays a lack of typical synaptic plasticity, enhanced calcium buffering and extrusion, and resilience to cell death following injury.
TextSentencer_T5 524-706 Sentence denotes Although recent studies have identified multiple molecular markers of area CA2, the proteins that mediate the unique physiology, signaling, and resilience of this region are unknown.
T5 524-706 Sentence denotes Although recent studies have identified multiple molecular markers of area CA2, the proteins that mediate the unique physiology, signaling, and resilience of this region are unknown.
TextSentencer_T6 707-866 Sentence denotes Using a transgenic GFP-reporter mouse line that expresses eGFP in CA2, we were able to perform targeted dissections of area CA2 and CA1 for proteomic analysis.
T6 707-866 Sentence denotes Using a transgenic GFP-reporter mouse line that expresses eGFP in CA2, we were able to perform targeted dissections of area CA2 and CA1 for proteomic analysis.
TextSentencer_T7 867-961 Sentence denotes We identified over 100 proteins with robustly enriched expression in area CA2 compared to CA1.
T7 867-961 Sentence denotes We identified over 100 proteins with robustly enriched expression in area CA2 compared to CA1.
TextSentencer_T8 962-1197 Sentence denotes Many of these proteins, including RGS14 and NECAB2, have already been shown to be enriched in CA2 and important for its function, while many more merit further study in the context of enhanced expression in this enigmatic brain region.
T8 962-1197 Sentence denotes Many of these proteins, including RGS14 and NECAB2, have already been shown to be enriched in CA2 and important for its function, while many more merit further study in the context of enhanced expression in this enigmatic brain region.
TextSentencer_T9 1198-1345 Sentence denotes Furthermore, we performed a comprehensive analysis of the entire data set (>2300 proteins) using a weighted protein co-expression network analysis.
T9 1198-1345 Sentence denotes Furthermore, we performed a comprehensive analysis of the entire data set (>2300 proteins) using a weighted protein co-expression network analysis.
TextSentencer_T10 1346-1498 Sentence denotes This identified eight distinct co-expressed patterns of protein co-enrichment associated with increased expression in area CA2 tissue (compared to CA1).
T10 1346-1498 Sentence denotes This identified eight distinct co-expressed patterns of protein co-enrichment associated with increased expression in area CA2 tissue (compared to CA1).
TextSentencer_T11 1499-1722 Sentence denotes The novel data set we present here reveals a specific CA2 hippocampal proteome, laying the groundwork for future studies and a deeper understanding of area CA2 and the proteins mediating its unique physiology and signaling.
T11 1499-1722 Sentence denotes The novel data set we present here reveals a specific CA2 hippocampal proteome, laying the groundwork for future studies and a deeper understanding of area CA2 and the proteins mediating its unique physiology and signaling.