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PubMed:30831029 JSONTXT 40 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-72 Sentence denotes Proteomic Identification of Protein Glutathionylation in Cardiomyocytes.
T1 0-72 Sentence denotes Proteomic Identification of Protein Glutathionylation in Cardiomyocytes.
TextSentencer_T2 73-237 Sentence denotes Reactive oxygen species (ROS) are important signaling molecules, but their overproduction is associated with many cardiovascular diseases, including cardiomyopathy.
T2 73-237 Sentence denotes Reactive oxygen species (ROS) are important signaling molecules, but their overproduction is associated with many cardiovascular diseases, including cardiomyopathy.
TextSentencer_T3 238-391 Sentence denotes ROS induce various oxidative modifications, among which glutathionylation is one of the significant protein oxidations that occur under oxidative stress.
T3 238-391 Sentence denotes ROS induce various oxidative modifications, among which glutathionylation is one of the significant protein oxidations that occur under oxidative stress.
TextSentencer_T4 392-522 Sentence denotes Despite previous efforts, direct and site-specific identification of glutathionylated proteins in cardiomyocytes has been limited.
T4 392-522 Sentence denotes Despite previous efforts, direct and site-specific identification of glutathionylated proteins in cardiomyocytes has been limited.
TextSentencer_T5 523-778 Sentence denotes In this report, we used a clickable glutathione approach in a HL-1 mouse cardiomyocyte cell line under exposure to hydrogen peroxide, finding 1763 glutathionylated peptides with specific Cys modification sites, which include many muscle-specific proteins.
T5 523-778 Sentence denotes In this report, we used a clickable glutathione approach in a HL-1 mouse cardiomyocyte cell line under exposure to hydrogen peroxide, finding 1763 glutathionylated peptides with specific Cys modification sites, which include many muscle-specific proteins.
TextSentencer_T6 779-1043 Sentence denotes Bioinformatic and cluster analyses found 125 glutathionylated proteins, whose mutations or dysfunctions are associated with cardiomyopathy, many of which include sarcomeric structural and contractile proteins, chaperone, and other signaling or regulatory proteins.
T6 779-1043 Sentence denotes Bioinformatic and cluster analyses found 125 glutathionylated proteins, whose mutations or dysfunctions are associated with cardiomyopathy, many of which include sarcomeric structural and contractile proteins, chaperone, and other signaling or regulatory proteins.
TextSentencer_T7 1044-1244 Sentence denotes We further provide functional implication of glutathionylation for several identified proteins, including CSRP3/MLP and complex I, II, and III, by analyzing glutathionylated sites in their structures.
T7 1044-1244 Sentence denotes We further provide functional implication of glutathionylation for several identified proteins, including CSRP3/MLP and complex I, II, and III, by analyzing glutathionylated sites in their structures.
TextSentencer_T8 1245-1444 Sentence denotes Our report establishes a chemoselective method for direct identification of glutathionylated proteins and provides potential target proteins whose glutathionylation may contribute to muscle diseases.
T8 1245-1444 Sentence denotes Our report establishes a chemoselective method for direct identification of glutathionylated proteins and provides potential target proteins whose glutathionylation may contribute to muscle diseases.