| Id |
Subject |
Object |
Predicate |
Lexical cue |
| TextSentencer_T1 |
0-149 |
Sentence |
denotes |
Identification of Abnormal Fucosylated-Glycans Recognized by LTL in Saliva of HBV-Induced Chronic Hepatitis, Cirrhosis, and Hepatocellular Carcinoma. |
| T1 |
0-149 |
Sentence |
denotes |
Identification of Abnormal Fucosylated-Glycans Recognized by LTL in Saliva of HBV-Induced Chronic Hepatitis, Cirrhosis, and Hepatocellular Carcinoma. |
| TextSentencer_T2 |
150-246 |
Sentence |
denotes |
The hepatitis B virus (HBV)-induced chronic liver diseases are serious health threats worldwide. |
| T2 |
150-246 |
Sentence |
denotes |
The hepatitis B virus (HBV)-induced chronic liver diseases are serious health threats worldwide. |
| TextSentencer_T3 |
247-379 |
Sentence |
denotes |
There is evidence to display the alterations of salivary N-linked glycans related to the development of HBV-infected liver diseases. |
| T3 |
247-379 |
Sentence |
denotes |
There is evidence to display the alterations of salivary N-linked glycans related to the development of HBV-infected liver diseases. |
| TextSentencer_T4 |
380-704 |
Sentence |
denotes |
Here, we further investigated the alterations of fucosylated N/O-glycans recognized by LTL in saliva from 120 subjects (30 healthy volunteers (HV), 30 patients with hepatitis B (HB), 30 patients with hepatic cirrhosis (HC), and 30 patients with hepatocellular carcinoma (HCC)) using salivary microarrys and MALDI-TOF/TOF-MS. |
| T4 |
380-704 |
Sentence |
denotes |
Here, we further investigated the alterations of fucosylated N/O-glycans recognized by LTL in saliva from 120 subjects (30 healthy volunteers (HV), 30 patients with hepatitis B (HB), 30 patients with hepatic cirrhosis (HC), and 30 patients with hepatocellular carcinoma (HCC)) using salivary microarrys and MALDI-TOF/TOF-MS. |
| TextSentencer_T5 |
705-866 |
Sentence |
denotes |
The results showed that the expression level of fucosylated glycans recognized by LTL was significantly increased in HCC compared with other subjects (p<0.0001). |
| T5 |
705-866 |
Sentence |
denotes |
The results showed that the expression level of fucosylated glycans recognized by LTL was significantly increased in HCC compared with other subjects (p<0.0001). |
| TextSentencer_T6 |
867-998 |
Sentence |
denotes |
Besides, the fucosylated glycoproteins were isolated from pooled saliva of HV, HB, HC, and HCC by LTL-magnetic particle conjugates. |
| T6 |
867-998 |
Sentence |
denotes |
Besides, the fucosylated glycoproteins were isolated from pooled saliva of HV, HB, HC, and HCC by LTL-magnetic particle conjugates. |
| TextSentencer_T7 |
999-1139 |
Sentence |
denotes |
Then, N/O- glycans were released from the isolated glycoproteins with PNGase F and NaClO, and were identified by MALDI-TOF-MS, respectively. |
| T7 |
999-1139 |
Sentence |
denotes |
Then, N/O- glycans were released from the isolated glycoproteins with PNGase F and NaClO, and were identified by MALDI-TOF-MS, respectively. |
| TextSentencer_T8 |
1140-1301 |
Sentence |
denotes |
Totally, there were 21/20, 25/18, 29/19, and 28/24 N/O-glycan peaks that were identified and annotated with proposed structures in saliva of HV, HB, HC, and HCC. |
| T8 |
1140-1301 |
Sentence |
denotes |
Totally, there were 21/20, 25/18, 29/19, and 28/24 N/O-glycan peaks that were identified and annotated with proposed structures in saliva of HV, HB, HC, and HCC. |
| TextSentencer_T9 |
1302-1517 |
Sentence |
denotes |
Among the total, there were 8 N-glycan peaks (e.g., m/z 1905.634, 2158.777 and 2905.036) and 15 O-glycan peaks (e.g., 1177.407, 1308.444 and 1322.444) that only presented in patients with HBV-induced liver diseases. |
| T9 |
1302-1517 |
Sentence |
denotes |
Among the total, there were 8 N-glycan peaks (e.g., m/z 1905.634, 2158.777 and 2905.036) and 15 O-glycan peaks (e.g., 1177.407, 1308.444 and 1322.444) that only presented in patients with HBV-induced liver diseases. |
| TextSentencer_T10 |
1518-1653 |
Sentence |
denotes |
One N-glycan peak (m/z 2205.766) was unique in HC, and 9 O-glycan peaks (e.g., m/z 1157.420, 1163.417 and 1193.402) were unique in HCC. |
| T10 |
1518-1653 |
Sentence |
denotes |
One N-glycan peak (m/z 2205.766) was unique in HC, and 9 O-glycan peaks (e.g., m/z 1157.420, 1163.417 and 1193.402) were unique in HCC. |
| TextSentencer_T11 |
1654-1791 |
Sentence |
denotes |
This study could facilitate the discovery of biomarkers for HC and HCC based on precise alterations of fucosylated N/O-glycans in saliva. |
| T11 |
1654-1791 |
Sentence |
denotes |
This study could facilitate the discovery of biomarkers for HC and HCC based on precise alterations of fucosylated N/O-glycans in saliva. |
