> top > projects > sentences > docs > PubMed:29277644 > annotations
sentences Home  

PubMed:29277644 JSONTXT 40 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-87 Sentence denotes Sex differences in murine myocardium are not exclusively regulated by gonadal hormones.
T1 0-87 Sentence denotes Sex differences in murine myocardium are not exclusively regulated by gonadal hormones.
TextSentencer_T2 88-223 Sentence denotes We investigated sex differences in cardiac protein patterns of intact and castrated mice using proteomics and 1D and 2D immunoblotting.
T2 88-223 Sentence denotes We investigated sex differences in cardiac protein patterns of intact and castrated mice using proteomics and 1D and 2D immunoblotting.
TextSentencer_T3 224-348 Sentence denotes To exclude differences concerning developmental aspects gonadectomy was conducted in mature mice at the age of three months.
T3 224-348 Sentence denotes To exclude differences concerning developmental aspects gonadectomy was conducted in mature mice at the age of three months.
TextSentencer_T4 349-552 Sentence denotes The main sex-related regulation in the protein pattern of the myocardium occurred for proteins involved in metabolic processes whereas only few proteins involved in other pathways underwent a regulation.
T4 349-552 Sentence denotes The main sex-related regulation in the protein pattern of the myocardium occurred for proteins involved in metabolic processes whereas only few proteins involved in other pathways underwent a regulation.
TextSentencer_T5 553-811 Sentence denotes Many regulated proteins (2/3) displayed a characteristic V form, which means that these proteins are up- or down-regulated in sexually mature compared to young mice and are back-regulated after castration, emphasizing a direct regulation by gonadal hormones.
T5 553-811 Sentence denotes Many regulated proteins (2/3) displayed a characteristic V form, which means that these proteins are up- or down-regulated in sexually mature compared to young mice and are back-regulated after castration, emphasizing a direct regulation by gonadal hormones.
TextSentencer_T6 812-1076 Sentence denotes Several other spots (1/3) showed the same male/female regulation or a drastic increase in male/female spot intensity ratio after castration, suggesting either a regulation independent of sex hormones or a removal of an inhibiting feedback mechanism by gonadectomy.
T6 812-1076 Sentence denotes Several other spots (1/3) showed the same male/female regulation or a drastic increase in male/female spot intensity ratio after castration, suggesting either a regulation independent of sex hormones or a removal of an inhibiting feedback mechanism by gonadectomy.
TextSentencer_T7 1077-1228 Sentence denotes Technically, we found that it cannot be expected that a single spot contains only one protein species and that one protein is present in only one spot.
T7 1077-1228 Sentence denotes Technically, we found that it cannot be expected that a single spot contains only one protein species and that one protein is present in only one spot.
TextSentencer_T8 1229-1426 Sentence denotes We thus propose for proteomic investigations to identify/quantify all spots of a 2-DE pattern to obtain information about protein speciation and its potential importance for function and pathology.
T8 1229-1426 Sentence denotes We thus propose for proteomic investigations to identify/quantify all spots of a 2-DE pattern to obtain information about protein speciation and its potential importance for function and pathology.
TextSentencer_T9 1427-1451 Sentence denotes BIOLOGICAL SIGNIFICANCE:
T9 1427-1451 Sentence denotes BIOLOGICAL SIGNIFICANCE:
TextSentencer_T10 1452-1707 Sentence denotes Sex related differences in cardiovascular disease, including risk factors, disease manifestation and outcomes, are far from being well understood, and improved biological understanding of these differences in the healthy myocardium is of great importance.
T10 1452-1707 Sentence denotes Sex related differences in cardiovascular disease, including risk factors, disease manifestation and outcomes, are far from being well understood, and improved biological understanding of these differences in the healthy myocardium is of great importance.
TextSentencer_T11 1708-1924 Sentence denotes We investigated sex related changes of myocardial protein pattern in intact and castrated mice at different ages and found metabolic proteins to be highly regulated, some of which independently from gonadal hormones.
T11 1708-1924 Sentence denotes We investigated sex related changes of myocardial protein pattern in intact and castrated mice at different ages and found metabolic proteins to be highly regulated, some of which independently from gonadal hormones.