| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T1 |
0-48 |
Sentence |
denotes |
Proteomic analysis of Bombyx mori molting fluid: |
| T1 |
0-48 |
Sentence |
denotes |
Proteomic analysis of Bombyx mori molting fluid: |
| T2 |
49-83 |
Sentence |
denotes |
Insights into the molting process. |
| T2 |
49-83 |
Sentence |
denotes |
Insights into the molting process. |
| T3 |
84-196 |
Sentence |
denotes |
Molting is an essential biological process occurring multiple times throughout the life cycle of most Ecdysozoa. |
| T3 |
84-196 |
Sentence |
denotes |
Molting is an essential biological process occurring multiple times throughout the life cycle of most Ecdysozoa. |
| T4 |
197-284 |
Sentence |
denotes |
Molting fluids accumulate and function in the exuvial space during the molting process. |
| T4 |
197-284 |
Sentence |
denotes |
Molting fluids accumulate and function in the exuvial space during the molting process. |
| T5 |
285-465 |
Sentence |
denotes |
In this study, we used liquid chromatography-tandem mass spectrometry to investigate the molting fluids to analyze the molecular mechanisms of molting in the silkworm, Bombyx mori. |
| T5 |
285-465 |
Sentence |
denotes |
In this study, we used liquid chromatography-tandem mass spectrometry to investigate the molting fluids to analyze the molecular mechanisms of molting in the silkworm, Bombyx mori. |
| T6 |
466-692 |
Sentence |
denotes |
In total, 375 proteins were identified in molting fluids from the silkworm at 14-16h before pupation and eclosion, including 12 chitin metabolism-related enzymes, 35 serine proteases, 15 peptidases, and 38 protease inhibitors. |
| T6 |
466-692 |
Sentence |
denotes |
In total, 375 proteins were identified in molting fluids from the silkworm at 14-16h before pupation and eclosion, including 12 chitin metabolism-related enzymes, 35 serine proteases, 15 peptidases, and 38 protease inhibitors. |
| T7 |
693-803 |
Sentence |
denotes |
Gene ontology analysis indicated that "catalytic" constitutes the most enriched function in the molting fluid. |
| T7 |
693-803 |
Sentence |
denotes |
Gene ontology analysis indicated that "catalytic" constitutes the most enriched function in the molting fluid. |
| T8 |
804-951 |
Sentence |
denotes |
Gene expression patterns and bioinformatic analyses suggested that numerous enzymes are involved in the degradation of cuticle proteins and chitin. |
| T8 |
804-951 |
Sentence |
denotes |
Gene expression patterns and bioinformatic analyses suggested that numerous enzymes are involved in the degradation of cuticle proteins and chitin. |
| T9 |
952-1111 |
Sentence |
denotes |
Protein-protein interaction network and activity analyses showed that protease inhibitors are involved in the regulation of multiple pathways in molting fluid. |
| T9 |
952-1111 |
Sentence |
denotes |
Protein-protein interaction network and activity analyses showed that protease inhibitors are involved in the regulation of multiple pathways in molting fluid. |
| T10 |
1112-1208 |
Sentence |
denotes |
Additionally, many immune-related proteins may be involved in the immune defense during molting. |
| T10 |
1112-1208 |
Sentence |
denotes |
Additionally, many immune-related proteins may be involved in the immune defense during molting. |
| T11 |
1209-1427 |
Sentence |
denotes |
These results provide a comprehensive proteomic insight into proteolytic enzymes and protease inhibitors in molting fluid, and will likely improve the current understanding of physiological processes in insect molting. |
| T11 |
1209-1427 |
Sentence |
denotes |
These results provide a comprehensive proteomic insight into proteolytic enzymes and protease inhibitors in molting fluid, and will likely improve the current understanding of physiological processes in insect molting. |
| T12 |
1428-1452 |
Sentence |
denotes |
BIOLOGICAL SIGNIFICANCE: |
| T12 |
1428-1452 |
Sentence |
denotes |
BIOLOGICAL SIGNIFICANCE: |
| T13 |
1453-1512 |
Sentence |
denotes |
Insect molting constitutes a dynamic physiological process. |
| T13 |
1453-1512 |
Sentence |
denotes |
Insect molting constitutes a dynamic physiological process. |
| T14 |
1513-1677 |
Sentence |
denotes |
To better understand this process, we used LC-MS/MS to investigate the proteome of silkworm molting fluids and identified key proteins involved in silkworm molting. |
| T14 |
1513-1677 |
Sentence |
denotes |
To better understand this process, we used LC-MS/MS to investigate the proteome of silkworm molting fluids and identified key proteins involved in silkworm molting. |
| T15 |
1678-1826 |
Sentence |
denotes |
The biological processes of the old cuticle degradation pathway and immune defense response were analyzed in the proteome of silkworm molting fluid. |
| T15 |
1678-1826 |
Sentence |
denotes |
The biological processes of the old cuticle degradation pathway and immune defense response were analyzed in the proteome of silkworm molting fluid. |
| T16 |
1827-1924 |
Sentence |
denotes |
We report that protease inhibitors serve as key factors in the regulation of the molting process. |
| T16 |
1827-1924 |
Sentence |
denotes |
We report that protease inhibitors serve as key factors in the regulation of the molting process. |
| T17 |
1925-2012 |
Sentence |
denotes |
The proteomic results provide new insight into biological molting processes in insects. |
| T17 |
1925-2012 |
Sentence |
denotes |
The proteomic results provide new insight into biological molting processes in insects. |