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PubMed:28616799 JSONTXT 39 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-95 Sentence denotes Dolichol phosphate mannose synthase: a Glycosyltransferase with Unity in molecular diversities.
T1 0-95 Sentence denotes Dolichol phosphate mannose synthase: a Glycosyltransferase with Unity in molecular diversities.
TextSentencer_T2 96-217 Sentence denotes N-glycans provide structural and functional stability to asparagine-linked (N-linked) glycoproteins, and add flexibility.
T2 96-217 Sentence denotes N-glycans provide structural and functional stability to asparagine-linked (N-linked) glycoproteins, and add flexibility.
TextSentencer_T3 218-313 Sentence denotes Glycan biosynthesis is elaborative, multi-compartmental and involves many glycosyltransferases.
T3 218-313 Sentence denotes Glycan biosynthesis is elaborative, multi-compartmental and involves many glycosyltransferases.
TextSentencer_T4 314-460 Sentence denotes Failure to assemble N-glycans leads to phenotypic changes developing infection, cancer, congenital disorders of glycosylation (CDGs) among others.
T4 314-460 Sentence denotes Failure to assemble N-glycans leads to phenotypic changes developing infection, cancer, congenital disorders of glycosylation (CDGs) among others.
TextSentencer_T5 461-681 Sentence denotes Biosynthesis of N-glycans begins at the endoplasmic reticulum (ER) with the assembly of dolichol-linked tetra-decasaccharide (Glc3Man9GlcNAc2-PP-Dol) where dolichol phosphate mannose synthase (DPMS) plays a central role.
T5 461-681 Sentence denotes Biosynthesis of N-glycans begins at the endoplasmic reticulum (ER) with the assembly of dolichol-linked tetra-decasaccharide (Glc3Man9GlcNAc2-PP-Dol) where dolichol phosphate mannose synthase (DPMS) plays a central role.
TextSentencer_T6 682-815 Sentence denotes DPMS is also essential for GPI anchor biosynthesis as well as for O- and C-mannosylation of proteins in yeast and in mammalian cells.
T6 682-815 Sentence denotes DPMS is also essential for GPI anchor biosynthesis as well as for O- and C-mannosylation of proteins in yeast and in mammalian cells.
TextSentencer_T7 816-946 Sentence denotes DPMS has been purified from several sources and its gene has been cloned from 39 species (e.g., from protozoan parasite to human).
T7 816-946 Sentence denotes DPMS has been purified from several sources and its gene has been cloned from 39 species (e.g., from protozoan parasite to human).
TextSentencer_T8 947-1066 Sentence denotes It is an inverting GT-A folded enzyme and classified as GT2 by CAZy (carbohydrate active enZyme; http://www.cazy.org ).
T8 947-1066 Sentence denotes It is an inverting GT-A folded enzyme and classified as GT2 by CAZy (carbohydrate active enZyme; http://www.cazy.org ).
TextSentencer_T9 1067-1258 Sentence denotes The sequence alignment detects the presence of a metal binding DAD signature in DPMS from all 39 species but finds cAMP-dependent protein phosphorylation motif (PKA motif) in only 38 species.
T9 1067-1258 Sentence denotes The sequence alignment detects the presence of a metal binding DAD signature in DPMS from all 39 species but finds cAMP-dependent protein phosphorylation motif (PKA motif) in only 38 species.
TextSentencer_T10 1259-1295 Sentence denotes DPMS also has hydrophobic region(s).
T10 1259-1295 Sentence denotes DPMS also has hydrophobic region(s).
TextSentencer_T11 1296-1452 Sentence denotes Hydropathy analysis of amino acid sequences from bovine, human, S. crevisiae and A. thaliana DPMS show PKA motif is present between the hydrophobic domains.
T11 1296-1452 Sentence denotes Hydropathy analysis of amino acid sequences from bovine, human, S. crevisiae and A. thaliana DPMS show PKA motif is present between the hydrophobic domains.
TextSentencer_T12 1453-1566 Sentence denotes The location of PKA motif as well as the hydrophobic domain(s) in the DPMS sequence vary from species to species.
T12 1453-1566 Sentence denotes The location of PKA motif as well as the hydrophobic domain(s) in the DPMS sequence vary from species to species.
TextSentencer_T13 1567-1656 Sentence denotes For example, the domain(s) could be located at the center or more towards the C-terminus.
T13 1567-1656 Sentence denotes For example, the domain(s) could be located at the center or more towards the C-terminus.
TextSentencer_T14 1657-1878 Sentence denotes Irrespective of their catalytic similarity, the DNA sequence, the amino acid identity, and the lack of a stretch of hydrophobic amino acid residues at the C-terminus, DPMS is still classified as Type I and Type II enzyme.
T14 1657-1878 Sentence denotes Irrespective of their catalytic similarity, the DNA sequence, the amino acid identity, and the lack of a stretch of hydrophobic amino acid residues at the C-terminus, DPMS is still classified as Type I and Type II enzyme.
TextSentencer_T15 1879-2001 Sentence denotes Because of an apparent bio-sensing ability, extracellular signaling and microenvironment regulate DPMS catalytic activity.
T15 1879-2001 Sentence denotes Because of an apparent bio-sensing ability, extracellular signaling and microenvironment regulate DPMS catalytic activity.
TextSentencer_T16 2002-2093 Sentence denotes In this review, we highlight some important features and the molecular diversities of DPMS.
T16 2002-2093 Sentence denotes In this review, we highlight some important features and the molecular diversities of DPMS.