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PubMed:28493026 JSONTXT 43 Projects

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Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-129 Sentence denotes Structural and functional characterization of a novel immunomodulatory glycoprotein isolated from ajowan (Trachyspermum ammi L.).
T1 0-129 Sentence denotes Structural and functional characterization of a novel immunomodulatory glycoprotein isolated from ajowan (Trachyspermum ammi L.).
TextSentencer_T2 130-249 Sentence denotes Ajowan (Trachyspermum ammi L.) spice has been used in food preparations and also as a traditional medicine in Ayurveda.
T2 130-249 Sentence denotes Ajowan (Trachyspermum ammi L.) spice has been used in food preparations and also as a traditional medicine in Ayurveda.
TextSentencer_T3 250-372 Sentence denotes Although a number of pharmacological activities have been attributed to ajowan, its role in immunomodulation is not known.
T3 250-372 Sentence denotes Although a number of pharmacological activities have been attributed to ajowan, its role in immunomodulation is not known.
TextSentencer_T4 373-474 Sentence denotes The main objective of the present study is to examine the macromolecular immunomodulatory components.
T4 373-474 Sentence denotes The main objective of the present study is to examine the macromolecular immunomodulatory components.
TextSentencer_T5 475-611 Sentence denotes Macrophage activation was studied by nitric oxide (NO) release, phagocytosis and secretion of pro-inflammatory cytokines as the markers.
T5 475-611 Sentence denotes Macrophage activation was studied by nitric oxide (NO) release, phagocytosis and secretion of pro-inflammatory cytokines as the markers.
TextSentencer_T6 612-756 Sentence denotes Ethanol precipitate (fractional) of ajowan aqueous extract was subjected to conventional chromatography (Q Sepharose followed by Bio-Gel P-100).
T6 612-756 Sentence denotes Ethanol precipitate (fractional) of ajowan aqueous extract was subjected to conventional chromatography (Q Sepharose followed by Bio-Gel P-100).
TextSentencer_T7 757-872 Sentence denotes One of the proteins (30.7 kDa; ajowan glycoprotein or Agp) showed effective mitogenic activity towards splenocytes.
T7 757-872 Sentence denotes One of the proteins (30.7 kDa; ajowan glycoprotein or Agp) showed effective mitogenic activity towards splenocytes.
TextSentencer_T8 873-969 Sentence denotes Agp is a O-linked glycoprotein with the glycans contributing to one-third of the molecular mass.
T8 873-969 Sentence denotes Agp is a O-linked glycoprotein with the glycans contributing to one-third of the molecular mass.
TextSentencer_T9 970-1160 Sentence denotes It has a high content of glutamic acid, serine, aspartic acid and proline whereas galactose (45.7%), arabinose (34.5%), glucose (7%), mannose (5%) and xylose (4%) are the constituent sugars.
T9 970-1160 Sentence denotes It has a high content of glutamic acid, serine, aspartic acid and proline whereas galactose (45.7%), arabinose (34.5%), glucose (7%), mannose (5%) and xylose (4%) are the constituent sugars.
TextSentencer_T10 1161-1252 Sentence denotes Secondary structure analysis indicated that Agp contains 79% α-helices and 21% random coil.
T10 1161-1252 Sentence denotes Secondary structure analysis indicated that Agp contains 79% α-helices and 21% random coil.
TextSentencer_T11 1253-1370 Sentence denotes Internal sequencing of the tryptic peptides did not show homology with the existing proteins in the database (BLAST).
T11 1253-1370 Sentence denotes Internal sequencing of the tryptic peptides did not show homology with the existing proteins in the database (BLAST).
TextSentencer_T12 1371-1525 Sentence denotes Agp at 1 μg/mL induced proliferation of B-cell enriched murine splenocytes and activated macrophages in releasing NO and promoted phagocytosis (p < 0.01).
T12 1371-1525 Sentence denotes Agp at 1 μg/mL induced proliferation of B-cell enriched murine splenocytes and activated macrophages in releasing NO and promoted phagocytosis (p < 0.01).
TextSentencer_T13 1526-1629 Sentence denotes RAW 264.7 cells produced pro-inflammatory cytokines (IL-12, TNF-α and IFN-γ) at 1 μg/mL Agp (p < 0.01).
T13 1526-1629 Sentence denotes RAW 264.7 cells produced pro-inflammatory cytokines (IL-12, TNF-α and IFN-γ) at 1 μg/mL Agp (p < 0.01).
TextSentencer_T14 1630-1781 Sentence denotes Deproteinized Agp (dpAgp) failed to elicit activation of murine immune cells, whereas deglycosylated Agp (20 kDa; dgAgp) showed compromised efficiency.
T14 1630-1781 Sentence denotes Deproteinized Agp (dpAgp) failed to elicit activation of murine immune cells, whereas deglycosylated Agp (20 kDa; dgAgp) showed compromised efficiency.
TextSentencer_T15 1782-1850 Sentence denotes This is the first report of an immunomodulatory protein from ajowan.
T15 1782-1850 Sentence denotes This is the first report of an immunomodulatory protein from ajowan.